Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Longer hospital stays do not mean better care

Physicians at The Johns Hopkins Hospital (JHH) have disproved the notion that longer hospital stays mean better care. They have successfully cut back on wait times across one dozen hospital departments and, as a result, reduced to well below six the average number of days patients with congestive heart failure, a need for dialysis or surgery, and many other conditions must spend in the hospital.

27 Sep 2005

Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in children

The Nonalcoholic Steatohepatitis (NASH) Clinical Research Network has launched its second clinical trial to study NASH, a liver disease that resembles alcoholic liver disease but occurs in patients who drink little or no alcohol. The first trial, launched in January of this year, focuses on adults, while the second trial studies the disease in children.

27 Sep 2005

Potential oral drug for rheumatoid arthritis

A potential oral drug for rheumatoid arthritis (RA) may encourage women to treat their condition earlier rather than later because it is less arduous than currently available treatments. Early treatment is important because RA most often develops between the ages of 35 and 50 and is two- to three times more prevalent in women.

26 Sep 2005

New way to create a permanent chemical bond between antibiotics and titanium

Infections associated with inserting a medical device can be devastating, painful, and cause prolonged disability, costing tens of thousands of dollars.

26 Sep 2005

Researchers map genetic location that explains why certain blood pressure-lowering drugs aren't effective for some people

"The findings bring us a step closer to developing targeted therapies for patients with high blood pressure who might otherwise be started on medications that won't help," said lead author Sandosh Padmanabhan, Ph.D.

26 Sep 2005

"Designer" rats help show how declining estrogen after menopause can affect hypertension

Scientists at Wake Forest University School of Medicine have created a better research rat – the first to enable them to study how declining estrogen after menopause can affect hypertension, heart failure and kidney damage.

26 Sep 2005

People who receive a kidney transplant are nearly four times more likely to develop melanoma

...a rare but deadly form of skin cancer, according to a study in the November 1, 2005 issue of Cancer, a peer-reviewed journal of the American Cancer Society.

26 Sep 2005

Genetically engineered animals help in scientific research that may benefit children

The recent use of genetically modified mice and rats in combination with an animal model of obstructive nephropathy, a type of renal disease, has given researchers new insight in the development of kidney disease.

21 Sep 2005

Important new lessons learned from aspirin

No other medicine is as common, inexpensive, and yet powerful in so many ways as aspirin; yet despite a century of experience with the drug, researchers are still learning important new lessons, while raising new questions, according to seven special articles in the Sept. 20, 2005, issue of the Journal of the American College of Cardiology.

20 Sep 2005

Periodontal disease develops much earlier than dentists and other health professionals thought

Periodontal disease -- a progressive, eventually painful and disruptive condition in which bacteria attack gums and the hidden roots of teeth -- develops much earlier than dentists and other health professionals thought, a major new study concludes.

20 Sep 2005

O-GlcNAc sugar is a critical regulator of cells' natural life cycle

The discovery reveals that, when disturbed, this process could contribute to cancer or other diseases by failing to properly control the steps and timing of cell division, the researchers say. The findings are described in the Sept. 23 issue of the Journal of Biological Chemistry, available online now.

20 Sep 2005

Low-dose aspirin might prevent the cardiovascular damage known to arise from use of the painkiller rofecoxib (Vioxx)

Their findings that a chemical imbalance might underlie such damage could also lead to the development of anti-inflammatory drugs without the adverse side effects, the researchers said.

20 Sep 2005

Key cellular switch that controls glucose production in liver cells

In many patients with type 2 diabetes, the liver acts like a sugar factory on overtime, churning out glucose throughout the day, even when blood sugar levels are high. Scientists at the Salk Institute for Biological Studies discovered a key cellular switch that controls glucose production in liver cells.

12 Sep 2005

Transplantation of organs from animals to humans could soon be a reality

Speaking at the BA Festival of Science in Dublin, Dr Anthony Warrens, discussed how xenotransplantation, the process of transplanting organs from one species into another, could soon be a reality, easing the current shortage of organs for transplantation.

10 Sep 2005

Inhaled-insulin drug Exubera - monitoring programme to be launched by Pfizer

Drug company Pfizer says it is all set to launch a patient-monitoring scheme in order to assess the safety of its novel inhaled-insulin drug Exubera, if the product is approved for use.

10 Sep 2005

It's pure science fiction! - human embryo to be created from two mothers

Scientists in Britain have been given permission to create a human embryo that will have genetic material from two mothers.

10 Sep 2005

Soldiers at risk for heat illnesses

A study reviewing 22 years of data on heat illness hospitalizations and deaths in the U.S. Army indicates soldiers remain at risk for exertional heat illness. While hospitalization rates for heat illnesses have declined over this period, cases of heat stroke have increased.

6 Sep 2005