Protein C News and Research

RSS

Using customized 'mini-antibodies' to mitigate chronic inflammation

Researchers at the Universities of Bonn and Sao Paulo have succeeded in mitigating chronic inflammation in mice using customized "mini-antibodies."

19 Apr 2022

New therapeutic option for HPV-positive head and neck carcinoma discovered

The various manifestations of head and neck carcinomas rank sixth in frequency worldwide and are fatal for about half a million people every year. In a quarter of cases, head and neck squamous cell carcinoma (HNSCC) is caused by human papillomavirus (HPV) and, currently, is not always treatable.

19 Apr 2022

Small genetic differences can affect the ability to utilize energy of various nutrients, study finds

Carbohydrates, proteins and fats are essential nutrients to all animals. Yet dietary variation between species, populations and individuals can vary dramatically.

19 Apr 2022

Why cheap, older drugs that might treat covid never get out of the lab

In March 2020, Dr. Joseph Vinetz left the contemplative world of his Yale University infectious-disease laboratory and plunged into the covid ward at Yale New Haven Hospital, joining an army of health care workers who struggled to treat the deadly viral disease.

19 Apr 2022

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Fighting cancer and chronic disease is tiring work for the immune system. When T cells are engaged in this kind of lengthy battle, they can become exhausted, or unable to function properly.

18 Apr 2022

Better understanding of hydrocephalus could lead to improved treatments

Hydrocephalus, or "water on the brain," occurs when the cerebral ventricles - four interconnected cavities of the brain that are filled with cerebrospinal fluid - become enlarged, but its cause is unknown in many cases.

18 Apr 2022

The brain's reaction to COVID's inflammatory tidal wave

Researchers study neuroinflammation in the cerebrospinal fluid and serum of patients infected with SARS-CoV-2.

18 Apr 2022

Research shows tsRNA as a promising biomarker for early diagnosis of hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is the most primary liver cancer. It is one of the most common and mortal cancer worldwide, especially in East Asia. Advanced HCC patients expect a significantly low 5-year survival rate as well as poor prognosis.

18 Apr 2022

Study investigates the production of a virosome-based COVID-19 vaccine candidate

In a new study, different signal peptides, baculovirus transfer vectors, cell lines, infection techniques, and formulation buffers were investigated with the purpose of building a scalable bioprocess to generate high-quality S protein for incorporation in a virosome-based COVID-19 vaccine candidate.

18 Apr 2022

Researchers uncover a key regulator of pregnancy-associated heart growth

Northwestern Medicine scientists have uncovered a key regulator of pregnancy-associated heart growth, according to a recent study published in the Journal of Clinical Investigation.

18 Apr 2022

The involvement of the skeletal muscles in long COVID-19

Researchers reviewed the mechanisms of muscle tissue injury, aggravating conditions, and associated sequelae in long COVID‐19.

18 Apr 2022

Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2

Researchers identified drugs inhibiting the entry of SARS-CoV-2.

18 Apr 2022

Scientists unravel the complex workings of the circadian rhythm in cyanobacteria

Scientists want to increase their understanding of circadian rhythms, those internal 24-hour biological clock cycles of sleeping and waking that occur in organisms, ranging from humans to plants to fungi to bacteria.

18 Apr 2022

Study predicts that different statins exhibit divergent effects on host response to SARS-CoV-2 infection

A new study explores the possibility that different statins may exhibit different effects within the host and may differ in their outcomes while treating COVID-19 patients.

18 Apr 2022

Mutation-acquiring potential of coronaviruses and efficacies of current COVID-19 vaccines against parent and mutant strains of SARS-CoV-2

Researchers reviewed the antibody resistance exhibited by SARS-CoV-2 variants.

18 Apr 2022

Monoclonal antibodies from COVID-19 convalescent donors target conserved site

Researchers found six monoclonal antibodies binding to the spike proteins of all human coronaviruses.

18 Apr 2022

RNA interference triggers that target SARS-CoV-2 genome

Researchers screened ribonucleic acid interference against SARS-CoV-2.

18 Apr 2022

SARS-CoV-2 RBD is a selective integrin agonist

Researchers assess the Arg-Gly-Asp (RGD) motif-mediated binding of the SARS-CoV-2 RBD and integrin receptors.

18 Apr 2022

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Researchers demonstrate that avasimibe-mediated inhibition of ACAT blocks the entry and fusion of SARS-CoV-2 in different cell types.

18 Apr 2022

Delivery technologies of mRNA and pDNA for advanced therapeutic applications

Innovation Center of NanoMedicine (Center Director: Prof. Kazunori Kataoka) has announced that Prof. Satoshi Uchida (Principal Research Scientist), who is also Associated Professor of the Kyoto Prefectural University of Medicine, published an article review about non-viral messenger RNA (mRNA) and plasmid DNA (pDNA) delivery by addressing the various delivery technologies of mRNA and pDNA, from basic research to therapeutic and clinical application; Pharmaceutics 2022, 14(4), 810.

15 Apr 2022

Protein C News and Research

Using customized 'mini-antibodies' to mitigate chronic inflammation

New therapeutic option for HPV-positive head and neck carcinoma discovered

Small genetic differences can affect the ability to utilize energy of various nutrients, study finds

Why cheap, older drugs that might treat covid never get out of the lab

New study pinpoints how immune checkpoint protein LAG3 modulates T cell activity

Better understanding of hydrocephalus could lead to improved treatments

The brain's reaction to COVID's inflammatory tidal wave

Research shows tsRNA as a promising biomarker for early diagnosis of hepatocellular carcinoma

Study investigates the production of a virosome-based COVID-19 vaccine candidate

Researchers uncover a key regulator of pregnancy-associated heart growth

The involvement of the skeletal muscles in long COVID-19

Study identifies Etravirine and Dolutegravir as effective entry inhibitors of wild-type and predominant variants of SARS-CoV-2

Scientists unravel the complex workings of the circadian rhythm in cyanobacteria

Study predicts that different statins exhibit divergent effects on host response to SARS-CoV-2 infection

Mutation-acquiring potential of coronaviruses and efficacies of current COVID-19 vaccines against parent and mutant strains of SARS-CoV-2

Monoclonal antibodies from COVID-19 convalescent donors target conserved site

RNA interference triggers that target SARS-CoV-2 genome

SARS-CoV-2 RBD is a selective integrin agonist

Avasimibe inhibits SARS-CoV-2 and boosts T-cell responses

Delivery technologies of mRNA and pDNA for advanced therapeutic applications

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Latest News