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Study identifies new mechanism involved in development of Lou Gehrig's disease

A new Tel Aviv University study identifies a previously unknown mechanism involved in the development of Lou Gehrig's disease, or amyotrophic lateral sclerosis.

23 May 2018

Celgene to share new and updated data around novel hematological therapies

Celgene Corporation today announced that data from a broad range of early and late stage studies evaluating Celgene investigational agents and investigational uses of marketed products will be presented at the 23rd European Hematology Association annual meeting in Stockholm, Sweden, from June 14-17, 2018.

22 May 2018

PanOptica doses first patient in Phase 1/2 dose-ranging clinical trial of PAN-90806

PanOptica, Inc., a private biopharmaceutical company focused on developing innovative ophthalmology therapies, today announced that the Company has dosed the first patient in a Phase 1/2 dose-ranging clinical trial of PAN-90806, a once-daily topical eye drop formulation of a small-molecule anti-vascular endothelial growth factor (anti-VEGF) for the treatment of neovascular eye diseases.

22 May 2018

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

Innate fear is an essential emotion for animals to avoid danger in a severe natural environment. Rodents kept in a laboratory also show instinctive fear behavior against the smell of predators such as foxes, cats or snakes despite having never seen them.

22 May 2018

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

ToolGen, Inc., a biotechnology company specializing in genome editing, today announced data demonstrating that blocking a molecular pathway that down-regulates T-cell activity with the Company’s CRISPR/Cas9 gene editing platform results in increased T-cell receptor signaling, in vitro, and in improved anti-tumor activity when tested against in a mouse glioblastoma tumor model.

22 May 2018

Proteins moderating nicotine dependence may help fat cells burn energy

The same proteins that moderate nicotine dependence in the brain may be involved in regulating metabolism by acting directly on certain types of fat cells, new research from the University of Michigan Life Sciences Institute shows.

22 May 2018

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Planning a trip to Mars? You'll want to remember your anti-radiation pills. NASA and private space companies like SpaceX plan to send humans to the red planet within the next 15 years--but among the major challenges facing future crewed space missions is how to protect astronauts from the dangerous cosmic radiation of deep space.

22 May 2018

Scientists identify new drug target to combat chikungunya virus

Scientists have identified a molecule found on human cells and some animal cells that could be a useful target for drugs against chikungunya virus infection and related diseases, according to new research published in the journal Nature.

21 May 2018

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

Researchers from the Albert Einstein College of Medicine in New York have discovered that a signaling protein elevated in patients with acute myeloid leukemia plays a much wider role in the disease than previously thought.

18 May 2018

Study: Macrophages play key role in maintaining stem cell niche of mammary gland

A new study finds that one of the toughest characters in the immune system, the macrophage, has a nurturing side, at least when it comes to guarding the developing breast.

18 May 2018

FDA OKs first non-opioid drug for adults with opioid withdrawal symptoms

The United States Food and Drugs Administration (FDA), in a statement this week, approved a new drug Lucemyra (lofexidine hydrochloride) for the treatment and alleviation of opioid symptom withdrawal symptoms in adults in whom the drugs have been withdrawn abruptly.

17 May 2018

Drug combination may prevent secondary stroke in certain patients, study shows

Results from an international clinical trial of more than 4880 participants, published in the New England Journal of Medicine, show that combining clopidogrel and aspirin following a small stroke or experiencing minor stroke symptoms decreases risk of a new stroke, heart attack or other ischemic event within 90 days.

17 May 2018

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Obsidian Therapeutics, Inc., a biotechnology company dedicated to the development of next-generation cell and gene therapies with pharmacologic operating systems, today announced that the company presented preclinical data on its regulated IL12 and IL15 programs at the Annual Meeting of the American Society of Gene and Cell Therapy in Chicago, IL.

17 May 2018

Study finds molecular handle that chikungunya virus uses to enter into cells and cause arthritis

Chikungunya virus is a growing threat to the United States and other regions of the world as the mosquito that carries the virus expands its reach. Telltale symptoms of chikungunya infection are fever and joint pain that last about a week.

17 May 2018

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

The U.S. Food and Drug Administration today approved Lucemyra (lofexidine hydrochloride) for the mitigation of withdrawal symptoms to facilitate abrupt discontinuation of opioids in adults.

17 May 2018

HKBU researchers develop metal based probes for imaging dopamine receptors in living cells

A team led by Dr Edmond Ma Dik-lung, Associate Professor of the Department of Chemistry of Hong Kong Baptist University has developed the world's first iridium(III)-based probes for imaging dopamine receptors in living cells.

16 May 2018

Study finds distinct exhausted T cells that could have implications for fighting different diseases

The battle between the human immune system and long-term, persisting infections and other chronic diseases such as cancer results in a prolonged stalemate

16 May 2018

Treatment for muscle wasting improved survival in pre-clinical cancer model

Researchers from the University of Jyväskylä in Finland have found that continued treatment of muscle wasting with a soluble growth factor receptor protein, produced at the University of Helsinki, improved survival in a pre-clinical cancer model without affecting the tumor size.

15 May 2018

Researchers to explore how to prevent stress-related chronic pain conditions

More than 50 million people in the United States suffer from pain in the absence of injury. This includes patients with migraines, fibromyalgia, irritable bowel syndrome and many other disorders.

15 May 2018

Study: Antibodies against hemorrhagic fever disarm two viruses of same family

Hemorrhagic fever viruses, so named for their ability to induce massive, and at times fatal, internal bleeding, captured the world's attention during the Ebola outbreak of 2014-2016 in West Africa.

15 May 2018

Receptor News and Research

Study identifies new mechanism involved in development of Lou Gehrig's disease

Celgene to share new and updated data around novel hematological therapies

PanOptica doses first patient in Phase 1/2 dose-ranging clinical trial of PAN-90806

Researchers discover unexpected chemosensor pathway for predator odor-evoked innate fear behaviors

ToolGen's CRISPR/Cas9 gene editing platform improves T-cell anti-tumor activity in mouse model

Proteins moderating nicotine dependence may help fat cells burn energy

Novel drug prevents memory impairment in mice exposed to simulated deep space radiation

Scientists identify new drug target to combat chikungunya virus

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

Study: Macrophages play key role in maintaining stem cell niche of mammary gland

FDA OKs first non-opioid drug for adults with opioid withdrawal symptoms

Drug combination may prevent secondary stroke in certain patients, study shows

Obsidian Therapeutics presents preclinical data on regulated IL12 and IL15 programs

Study finds molecular handle that chikungunya virus uses to enter into cells and cause arthritis

FDA approves new treatment to mitigate opioid withdrawal symptoms in adults

HKBU researchers develop metal based probes for imaging dopamine receptors in living cells

Study finds distinct exhausted T cells that could have implications for fighting different diseases

Treatment for muscle wasting improved survival in pre-clinical cancer model

Researchers to explore how to prevent stress-related chronic pain conditions

Study: Antibodies against hemorrhagic fever disarm two viruses of same family

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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