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Experimental Alzheimer's drug begins clinical trials

A drug based on the design of a Purdue University researcher to treat Alzheimer's disease began the first phase of human clinical trials this week.

23 Jun 2007

Goltz syndrome gene found

Researchers funded in part by the National Institutes of Health have identified the gene that accounts for most cases of Goltz syndrome, a rare skin disorder that can also affect bone and eye development.

23 Jun 2007

Smoking affects ligament healing

The list of reasons you shouldn't smoke has gotten longer. Researchers at Washington University School of Medicine in St. Louis are reporting that smoking interferes with ligament healing.

23 Jun 2007

Women's perspectives on male circumcision as HIV prevention method

PlusNews/Mail & Guardian on Wednesday examined women's perspectives on male circumcision as an HIV prevention method. Informal discussions with women "reveal a range of concerns, preferences and views" that governments and researchers should consider before planning a national circumcision program, PlusNews/Mail & Guardian reports (PlusNews/Mail & Guardian, 6/20).

22 Jun 2007

Turn-ons and turn-offs for neurons

Our brain consists of billions of nerve cells enabling to learn, remember and reason.

20 Jun 2007

Two complementary commanders in charge of the brain

A probe of the upper echelons of the human brain's chain-of-command has found strong evidence that there are not one but two complementary commanders in charge of the brain, according to neuroscientists at Washington University School of Medicine in St. Louis.

20 Jun 2007

Ethical dilemma of international tissue donation

When the world's poorest sell their bodies to the world's wealthiest in the international tissue donation market they often secure their economic health at the cost of their physical health.

19 Jun 2007

Research on rare women's lung disease may yield insights into common diseases

For many decades, medical research studies focused primarily on men and the results of countless studies were then applied to women.

18 Jun 2007

New area of stroke drug discovery for the 22nd century

A new therapy to re-activate silenced genes in patients who suffer from neurodegenerative diseases or stroke is being developed by researchers at the University of Illinois at Chicago and Cornell University.

17 Jun 2007

New rheumatoid arthritis genes identified

Researchers at the University of Manchester have identified evidence of several new genes behind the chronic inflammatory disease rheumatoid arthritis (RA), which affects 387,000 people in the UK.

16 Jun 2007

New data on the performance of meningitis vaccine in West African children

The Meningitis Vaccine Project (MVP) today released new data on the performance of a meningitis vaccine in West African children, suggesting that the new vaccine,expected to sell initially for 40 US cents a dose,will be much more effective in protecting African children and their communities than any vaccine currently on the market in the region.

14 Jun 2007

What makes people susceptible to rheumatoid arthritis?

Peter K. Gregersen, MD, stares at x-rays of hands, searching out the telltale signs of inflamed joints and wrists from his research subjects with rheumatoid arthritis. With these clinical features at his side, he turns to the basic building blocks of life , the human genome , to figure out what makes these people susceptible to the disabling inflammatory condition.

14 Jun 2007

Gamma-secretase acts as a tumor suppressor

Researchers at Burnham Institute for Medical Research (Burnham) have provided the first evidence that gamma-secretase, an enzyme key to the progression of Alzheimer's, acts as a tumor suppressor by altering the pathway of epidermal growth factor receptor (EGFR), a potential treatment target for cancer.

14 Jun 2007

New genes involved in rheumatoid arthritis discovered

Researchers at the University of Manchester have identified evidence of several new genes behind the chronic inflammatory disease rheumatoid arthritis (RA), which affects 387,000 people in the UK.

From The University of Manchester 8 Jun 2007

Gene found that increases risk for Alzheimer's disease

A study comparing more genetic markers in the DNA of people with and without Alzheimer's disease than ever before has enabled researchers to identify a common gene that appears to increase a person's risk for developing Alzheimer's disease.

8 Jun 2007

Largest ever genetics study of common diseases

The Wellcome Trust Case Control Consortium, the largest ever study of the genetics behind common diseases such as diabetes, rheumatoid arthritis and coronary heart disease, publishes its results in the journals Nature and Nature Genetics.

8 Jun 2007

Obese women can lose weight and it won't hurt the baby

Most women who are obese can safely exercise and diet to lose weight during pregnancy, according to a small pilot study conducted by Saint Louis University researchers.

8 Jun 2007

In mice, drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online in Nature.

8 Jun 2007

Sertraline does not improve symptoms in some cancer patients without major depression

The established antidepressant sertraline does not improve symptoms, wellbeing or survival in patients with advanced cancer who do not have major depression.

5 Jun 2007

Research points to a broadly-protective HIV vaccine

New research conducted at the Uniformed Services University of the Health Sciences (USU) suggests that it may be possible to develop a vaccine that protects against the myriad strains of the HIV virus.

1 Jun 2007