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Researchers find new pig virus to be possible threat to humans

A recently identified pig virus can readily find its way into laboratory-cultured cells of people and other species, a discovery that raises concerns about the potential for outbreaks that threaten human and animal health.

15 May 2018

Heart failure severity could vary based on the body's nitric oxide levels

The most common heart medications may get an assist from nitric oxide circulating in the body, according to a new study out of Case Western Reserve University School of Medicine.

14 May 2018

Protein researchers identify several new potential targets for cancer

In a new study based on mouse cells internationally leading protein researchers have identified several new potential targets using state-of-the-art technology, many of which could be employed for future treatment of different types of cancers and diseases.

14 May 2018

Research may pave way for new C. diff antitoxins and anti-cancer drugs

Researchers from the University of California, Irvine and Harvard University have discovered how the Clostridium difficile toxin B recognizes the human Frizzled protein, the receptor it uses to invade intestinal cells and lead to deadly gastrointestinal infections.

14 May 2018

UCLA researchers identify receptor that plays key role in repairing damage caused by heart conditions

Studies have shown that a simple treatment called lipid emulsion therapy - fatty acids administered intravenously - can heal damage to the heart after a heart attack or cardiac arrest. But researchers haven't understood exactly how the treatment works or whether there are more effective ways to repair the heart.

14 May 2018

Researchers identify serotonin receptor that could be targeted to boost memory

In a breakthrough that could one day help individuals with cognitive impairment, researchers at Columbia University Irving Medical Center identified a specific receptor related to the neurotransmitter serotonin that could be targeted with drugs to boost memory.

11 May 2018

Enhancing the effects of vitamin D to curb type 2 diabetes

More than 27 million people in the United States are living with type 2 diabetes, according to the Centers for Disease Control and Prevention. As the population ages and a growing percentage of people become overweight or obese, that number is expected to increase.

10 May 2018

New case study shows CAR T therapy as viable option for AML patients

Chimeric Antigen Receptor T-cell therapy, also known as CAR T therapy, was named the biggest research breakthrough of 2017 by the American Society of Clinical Oncology. The personal gene therapy utilizes a patient's own immune cells to fight cancer.

9 May 2018

Research findings could lead to new therapies to curb ovarian cancer metastasis

In order to spread their destruction, ovarian cancer cells must break free from their tumor home, travel through the fluid in the peritoneal cavity and attach to the outside of the abdominal organs--surfaces that are, by necessity, not sticky.

9 May 2018

ONC201 disrupts mitochondrial function and kills breast cancer cells, reveals study

TRAIL, a member of the TNF family of ligands, causes caspase-dependent apoptosis through activation of its receptors, death receptor 4 and DR5.

9 May 2018

New drug-based treatment to promote weight loss in young patients with genetic obesity

In a new study researchers from the Institute for Experimental Pediatric Endocrinology of the Charité - Universitätsmedizin Berlin have successfully treat patients whose obesity is caused by a genetic defect.

8 May 2018

Study identifies new biomarker for early lung cancer diagnosis

High levels of cytoskeleton-associated protein 4 (CKAP4) have been identified in the blood of patients with lung cancer.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

UH professor receives NIH grant to protect kidneys from obesity

UH professor of pharmacology Tahir Hussain has received $1.6M from the National Institutes of Health to examine a kidney cell that could prevent damage from inflammation caused by obesity.

7 May 2018

Researchers discover how key brain receptor can function in hostile environment

During a stroke or an epileptic seizure, neurons in affected parts of the brain fire at an abnormally rapid rate.

7 May 2018

Researchers uncover novel approach for treating neuropathic pain

Neuropathic pain is the chronic, pathological pain that continues even when the cause of pain is removed. Causes include damage to nerve cells and medicines used to treat cancer.

4 May 2018

Keck School of Medicine of USC wins two grants to support osteoarthritis research

A researcher at the Keck School of Medicine of USC has been awarded two grants totaling more than $4 million to support osteoarthritis research.

4 May 2018

Osteoporosis drug prevents spread of basal-like breast cancer in mice

Researchers in China have discovered that an enzyme called UGT8 drives the progression of basal-like breast cancer, an aggressive form of the disease that is largely untreatable.

4 May 2018

Targeted 'click-to-release' chemotherapy leads to potent antitumor activity in mice

Antibody Drug Conjugates are relatively new anti-cancer drugs. They consist of an antibody to which a cell-killing molecule (chemotherapy) is attached. Antibodies can recognize and bind to certain receptors (the 'hands' on the outside of a cell) in a very targeted way.

4 May 2018

Scientists successfully test anti-alcoholism drug in animal models

Scientists at The University of Texas at Austin have successfully tested in animals a drug that, they say, may one day help block the withdrawal symptoms and cravings that incessantly coax people with alcoholism to drink.

4 May 2018