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Liquid biopsies could be used as new predictive marker for metastatic TNBC

A clinically relevant "liquid biopsy" test can be used to profile cancer genomes from blood and predict survival outcomes for patients with metastatic triple negative breast cancer, according to new research published by a multi-institutional team of researchers with The Ohio State University Comprehensive Cancer Center -- Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, the Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

19 Feb 2018

Researchers uncover how excess calcium may influence development of Parkinson’s disease

Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson's disease.

19 Feb 2018

Early childhood immune signature predicts risk of developing asthma later on

Asthma is a chronic inflammatory disease driven by the interplay of genetics, environmental factors and a diverse cast of immune cells.

19 Feb 2018

Poor awareness among parents may hinder a child's early dental care

A new survey has found that one in six parents are likely to postpone their children’s dental care visits until the age of 4 or older.

19 Feb 2018

Research finds rising trend in incidence of merkel cell carcinoma

Merkel cell carcinoma is a rare type of skin cancer, affecting only a few thousand people each year, compared to tens of thousands with melanoma. But while it may not be as common as other skin cancers, MCC is highly aggressive and often deadly - and it's also becoming more common, according to new research published in the Journal of the American Academy of Dermatology and presented at the American Academy of Dermatology 2018 Annual Meeting in San Diego.

19 Feb 2018

Researchers uncover Ras protein's role in uncontrolled cancer growth

Protein systems, such as Ras, make up the complex signaling pathways that control whether a cell divides or, in some cases, becomes cancerous and metastasizes into other regions of the body. For example, 98 percent of pancreatic cancers show Ras protein mutations.

19 Feb 2018

Study sheds light on biology that guides behavior across different stages of life

Put 50 newborn worms in 50 separate containers, and they'll all start looking for food at roughly the same time. Like members of other species, microscopic C. elegans roundworms tend to act like other individuals their own age.

19 Feb 2018

Myriad's EndoPredict offers better prediction of breast cancer recurrence, analysis shows

Myriad Genetics, Inc. today announced that a comparative analysis of commercially available prognostic breast cancer tests in patients with early-stage breast cancer has been published in JAMA Oncology.

19 Feb 2018

Scientists develop fluorescent probe to identify cancer stem cells

Cells with stem-cell characteristics appear to be especially important in the formation and metastasis of tumors. Scientists have now developed a universal fluorescent probe for these “cancer stem cells”. As reported in the journal Angewandte Chemie, this dye also selectively kills off the cells.

19 Feb 2018

Russian researchers develop new multi-layered biodegradable scaffolds

A team of young researchers at the National University of Science and Technology has recently presented its new development – therapeutic material based on nanofibers of polycaprolactone, modified with plasma-deposited thin layers enriched with antibacterial composition and human blood plasma components.

19 Feb 2018

University Hospital of Santiago de Compostela participates in large pancreatic cancer study

International validation through collaboration with leading cancer centers in Europe and US is a key part of Immunovia’s development and commercialization strategy for its portfolio of IMMray tests.

19 Feb 2018

New blood test shows promise to revolutionize diagnosis of tick-borne diseases

A new blood test called the Tick-Borne Disease Serochip (TBD Serochip) promises to revolutionize the diagnosis of tick-borne disease by offering a single test to identify and distinguish between Borrelia burgdorferi, the pathogen responsible for Lyme disease, and seven other tick-borne pathogens.

18 Feb 2018

Psoriasis drug also effective at reducing aortic inflammation

Ustekinumab, sold under the name Stelara, is approved by the U.S. Food and Drug Administration to treat psoriasis, psoriatic arthritis, and Crohn's Disease. Researchers wanted to know if the benefits of the drug go beyond clearing the skin.

18 Feb 2018

Study reveals parents' views toward children’s tanning bed use

While everyone who climbs into an indoor tanning bed faces an increased risk of skin cancer, this risk is especially pronounced for young people: Using indoor tanning beds before age 35 can increase one's risk of melanoma, the deadliest form of skin cancer, by 59 percent, and this risk increases with each use.

18 Feb 2018

Shot may help reduce risk of shingles

Anyone who has had chickenpox or the chickenpox vaccine is at risk for the painful skin condition herpes zoster, more commonly known as shingles. Both diseases are caused by the varicella-zoster virus, which stays in the body after chickenpox clears and may reactivate later in life.

18 Feb 2018

FDA approves first treatment to reduce risk of NSCLC progression

The U.S. Food and Drug Administration today approved Imfinzi (durvalumab) for the treatment of patients with stage III non-small cell lung cancer (NSCLC) whose tumors are not able to be surgically removed (unresectable) and whose cancer has not progressed after treatment with chemotherapy and radiation (chemoradiation).

18 Feb 2018

Deletion of specific enzyme leads to improvement in memory and cognitive functions

A new study in mice has made a possible breakthrough in Alzheimer’s research. The team of researchers at the Cleveland Clinic has noted that deleting a single enzyme can reverse the deposition of harmful plaques in the brains of patients with Alzheimer’s disease. This could improve cognitive functions as demonstrated in lab mice. The study appeared this week in the latest issue of the Journal of Experimental Medicine.

17 Feb 2018

Resolving Interfacial Protein Dynamics by STReM

STReM stands for Super Time-Resolved Microscopy, and as STORM, PALM, and other methods are designed to improve spatial resolution of optical microscopy, we desire to improve the time resolution. STReM makes use of point spread function engineering to encode fast events into each camera frame.

From Pittcon 16 Feb 2018

Study provides new insights on why healthy children die from flu

With this year's severe flu season, one statistic is especially chilling. Each year, around 50 percent of all children under 5 years old who die from the flu were previously healthy, according to the Centers for Disease Control and Prevention (CDC).

16 Feb 2018