Aspirin News and Research

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Aspirin also known as acetylsalicylic acid is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin also has an antiplatelet, or "anti-clotting", effect and is used in long-term, low doses to prevent heart attacks, strokes and blood clot formation in people at high risk for developing blood clots. It has also been established that low doses of aspirin may be given immediately after a heart attack to reduce the risk of another heart attack or of the death of cardiac tissue.

Physical, verbal reminders could improve preoperative preparation

Patients may be unable to recall much of the preoperative information they are given by anesthesiologists, suggesting the need for reminders such as printed instructions, and telephone calls the night before their procedure is scheduled, says a US research team.

30 Aug 2012

Chronic nerve pain: an interview with Professor Sally Lawson

Chronic nerve pain results from pathological changes within a nerve that appear to be self-sustaining and thus the pain continues for a long time.

30 Aug 2012

Combination of POZEN’s PA32540 and clopidogrel results in greater antiplatelet effects

POZEN Inc., a pharmaceutical company committed to transforming medicine that transforms lives, announced the presentation of Phase 1 data, at the European Society of Cardiologists 2012 Congress, from a study of PA32540, a novel coordinated-delivery tablet of enteric-coated (EC) aspirin (325 mg) and immediate-release (IR) omeprazole (40 mg).

30 Aug 2012

AstraZeneca’s ticagrelor receives Class I recommendation from ESC

AstraZeneca today announced that ticagrelor, an oral antiplatelet medicine, received a Class I recommendation from the European Society of Cardiology (ESC) in the revised "Guidelines on the Management of Acute Myocardial Infarction in Patients Presenting with Persistent ST-Segment Elevation (STEMI)" guidelines.

29 Aug 2012

Omitting aspirin leads to less bleedings but does not increase risk of stent thrombosis, MI

Lifelong anticoagulation is necessary for the prevention of stroke in patients with rhythm disturbances and with mechanical valves. Patients who have a coronary stent implanted also need the antiplatelet drugs aspirin and clopidogrel to prevent the rare but lethal complication of stent thrombosis.

29 Aug 2012

Risk of stroke after myocardial infarction seems to decrease with improvements in coronary care

The analysis of data from two Swedish registries was presented by Dr Anders Ulvenstam, and suggests that the reduction is due to improvements in AMI care.

29 Aug 2012

Taking aspirin associated with reduced risk of death from prostate cancer

Men who have been treated for prostate cancer, either with surgery or radiation, could benefit from taking aspirin regularly, says a new study that includes a researcher at UT Southwestern Medical Center.

29 Aug 2012

Global platelet reactivity effectively identifies ACS patients at high risk of ischemic events

Global platelet reactivity is more effective than responsiveness to clopidogrel in identifying acute coronary syndrome (ACS) patients at high risk of ischemic events, according to research presented at the ESC Congress today. The results from the RECLOSE 2-ACS study were presented by Dr Rossella Marcucci from Italy.

28 Aug 2012

Personalized antiplatelet treatment leads to better outcomes in patients undergoing PCI

Personalized antiplatelet treatment leads to better outcomes than standard antiplatelet treatment in patients undergoing coronary stent implantation, according to results from the MADONNA study presented at ESC Congress 2012.

28 Aug 2012

Insulin glargine retards progression of atherosclerosis in high-risk people

A sub-study of the Outcome Reduction with an Initial Glargine Intervention (ORIGIN) trial, designed to investigate the effect of insulin glargine and omega-3 fatty acids on atherosclerosis progression, has found that, compared to standard care, only insulin glargine (a long-acting insulin) had a "modest" statistically non-significant reducing effect on the primary outcome of rate of change in maximum carotid intima media thickness (CIMT) at 12 carotid sites.

27 Aug 2012

Study explores gender-related differences in patients hospitalized for acute heart failure

Women with acute heart failure have similar in-hospital mortality to men but are less treated in the real world, according to results from the global ALARM-HF registry presented today at the ESC Congress 2012. The findings were presented by Dr John T. Parissis from Greece.

27 Aug 2012

Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death

The first trial to study patients with acute coronary syndrome who do not undergo coronary stenting or bypass surgery found no significant difference between two anti-clotting drugs - prasugrel and clopidogrel - in preventing the first occurrence of death, heart attack or stroke, according to Duke University Medical Center cardiologists.

27 Aug 2012

CKD may raise stroke, bleeding risk in AF patients

Danish study results show that the presence of chronic kidney disease appears to raise the risk for stroke, systemic thromboembolism, and bleeding among patients with atrial fibrillation.

22 Aug 2012

Coronary artery calcium tool proves effective in detecting risk of cardiovascular disease

Heart calcium scans are far superior to other assessment tools in predicting the development of cardiovascular disease in individuals currently classified at intermediate risk by their doctors, according to researchers at Wake Forest Baptist Medical Center.

22 Aug 2012

CKD may raise stroke, bleeding risk in AF patients

Danish study results show that the presence of chronic kidney disease appears to raise the risk for stroke, systemic thromboembolism, and bleeding among patients with atrial fibrillation.

21 Aug 2012

PD risk factors for potential clinical screening identified

A meta-analysis has identified 19 risk factors that significantly impact a person’s risk for Parkinson’s disease and could be of potential value for clinical screening, say the authors.

20 Aug 2012

Political cartoon: 'A Little Extra Slice?'

Kaiser Health News provides a fresh take on health policy developments with "A Little Extra Slice?" by Jerry King.

20 Aug 2012

Daily aspirin use may reduce overall cancer mortality

Daily aspirin usage is associated with lower overall cancer mortality, but the association may be smaller than what was previously believed, according to a study published August 10 in the Journal of the National Cancer Institute.

12 Aug 2012

HCRI announces successful completion of randomization in DAPT Study

The Harvard Clinical Research Institute (HCRI) announced today the successful completion of randomization in the DAPT Study, with the total number of patients randomized exceeding the upper goal set for the Study.

8 Aug 2012

Training nurse-pharmacist teams to track discrepancies between patients medications at home and in hospital may reduce conflicts

A study of more than 500 patients admitted to, and discharged from, a big-city medical center suggests that nurse-pharmacist teams trained to track down discrepancies between lists of drugs patients are taking at home and those they are scheduled to take in the hospital might substantially reduce such potentially harmful conflicts.

1 Aug 2012

Aspirin News and Research

Physical, verbal reminders could improve preoperative preparation

Chronic nerve pain: an interview with Professor Sally Lawson

Combination of POZEN’s PA32540 and clopidogrel results in greater antiplatelet effects

AstraZeneca’s ticagrelor receives Class I recommendation from ESC

Omitting aspirin leads to less bleedings but does not increase risk of stent thrombosis, MI

Risk of stroke after myocardial infarction seems to decrease with improvements in coronary care

Taking aspirin associated with reduced risk of death from prostate cancer

Global platelet reactivity effectively identifies ACS patients at high risk of ischemic events

Personalized antiplatelet treatment leads to better outcomes in patients undergoing PCI

Insulin glargine retards progression of atherosclerosis in high-risk people

Study explores gender-related differences in patients hospitalized for acute heart failure

Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death

CKD may raise stroke, bleeding risk in AF patients

Coronary artery calcium tool proves effective in detecting risk of cardiovascular disease

CKD may raise stroke, bleeding risk in AF patients

PD risk factors for potential clinical screening identified

Political cartoon: 'A Little Extra Slice?'

Daily aspirin use may reduce overall cancer mortality

HCRI announces successful completion of randomization in DAPT Study

Training nurse-pharmacist teams to track discrepancies between patients medications at home and in hospital may reduce conflicts

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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