Cell Death News and Research

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Study sheds new insight into the dynamics of neural stem cell niche

When it comes to cell types, stem cells have unlimited potential – literally. These self-renewing cells, which are capable of giving rise to any cell type in the body, reside in specialized microenvironments known as niches.

16 Mar 2023

Cuproptosis-associated ferroptosis genes linked with immune infiltration in atherosclerosis

Announcing a new article publication for Cardiovascular Innovations and Applications journal. In this study, the authors identify cuproptosis-associated ferroptosis genes in the atherosclerosis microarray of the Gene Expression Omnibus (GEO) database and explored hub gene-mediated immune infiltration in atherosclerosis.

15 Mar 2023

New biomimetic model helps study wound healing in burn and laceration wounds

Burn wounds are notoriously prone to bacterial infection and typically lead to a larger amount of scar tissue than laceration wounds.

15 Mar 2023

Newly identified small molecule may help treat people with drug-resistant epilepsy

Researchers at Tufts University School of Medicine and colleagues have identified a small molecule that may help treat people with epilepsy whose condition has become resistant to the benzodiazepine drugs usually used in managing seizures.

15 Mar 2023

Study sheds new light on a key protein involved in the process of spermiation

In order to achieve good times in their races, many Olympic swimmers wear swimsuits that are low in water resistance.

13 Mar 2023

New insights into how spider lily compound kills cancer cells while keeping healthy cells intact

A scientific instrument at the Department of Energy's Oak Ridge National Laboratory could help create a noninvasive cancer treatment derived from a common tropical plant.

10 Mar 2023

Study finds cannabis vaping more harmful than nicotine vaping

A study published in the journal Thorax compares the pulmonary effects of vaping nicotine and cannabis. The study finds that cannabis is more harmful to lung health than nicotine.

5 Mar 2023

Studying gut bacteria's role in muscle regeneration and recover

In a surprising discovery, Harvard Medical School researchers have found that a class of regulatory T cells (Tregs) made in the gut play a role in repairing injured muscles and mending damaged livers.

2 Mar 2023

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Understanding how the knee joint environment affects cartilage cells is crucial for joint health. Knowledge of cell-driven cartilage degeneration mechanisms can support the development of effective pharmaceutical interventions for osteoarthritis.

1 Mar 2023

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

1 Mar 2023

PARK2 duplication or microdeletion and neurological diseases

In a recent study published in the Genes journal, researchers assessed the impact of PARK2 duplication or microdeletion on neurological diseases such as Parkinson's.

28 Feb 2023

Critical COVID-19 infection characterized by a shift from naïve T cell phenotypes to an expansion of cytotoxic CD4+ T lymphocyte subsets

Researchers immunophenotyped T lymphocyte responses among unvaccinated individuals, representative of the entire spectrum of the clinical presentation of COVID-19.

28 Feb 2023

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

A team of international scientists has recently characterized the structure of tumor necrosis factor receptor associated factor 6 (TRAF6) N-terminal domain for therapeutic purposes.

28 Feb 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

NQO2 gene as a novel potential target in Parkinson’s disease

A new study under review at the journal Scientific Reports and currently available on the Research Square* preprint server aimed to analyze the toxic effects of 6OHDA along with a related role of NQO2 in murine and human astrocytes.

23 Feb 2023

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer's disease and to lower cholesterol.

23 Feb 2023

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone.

23 Feb 2023

Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells

Researchers assessed the impact of COVID-19 on fibrotic pathogenesis via the deregulation of mitochondrial beta-oxidation.

23 Feb 2023

Study links obesity with 21 Alzheimer's disease-related genes

In a new study, researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) link obesity with 21 Alzheimer's disease-related genes, providing a potential mechanistic explanation for why Alzheimer's is sometimes more frequent among adults who experienced obesity in midlife.

22 Feb 2023

Research identifies potential treatment target for infantile spasms syndrome

New research from Tufts University School of Medicine and the Graduate School of Biomedical Sciences suggests that the timing of the death of certain inhibitory neurons in the brain shortly after birth may be at least partly to blame for infantile spasms syndrome (ISS), a rare but devastating form of epilepsy that develops most frequently between four and eight months of age but can emerge within weeks of birth until ages 4 or 5.

21 Feb 2023

Cell Death News and Research

Study sheds new insight into the dynamics of neural stem cell niche

Cuproptosis-associated ferroptosis genes linked with immune infiltration in atherosclerosis

New biomimetic model helps study wound healing in burn and laceration wounds

Newly identified small molecule may help treat people with drug-resistant epilepsy

Study sheds new light on a key protein involved in the process of spermiation

New insights into how spider lily compound kills cancer cells while keeping healthy cells intact

Study finds cannabis vaping more harmful than nicotine vaping

Studying gut bacteria's role in muscle regeneration and recover

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

PARK2 duplication or microdeletion and neurological diseases

Critical COVID-19 infection characterized by a shift from naïve T cell phenotypes to an expansion of cytotoxic CD4+ T lymphocyte subsets

Study characterizes N-terminal domain structure of a ubiquitin ligase TRAF6

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

NQO2 gene as a novel potential target in Parkinson’s disease

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Pathogenicity of SARS-CoV-2 viral components on human periodontal tissues and cells

Study links obesity with 21 Alzheimer's disease-related genes

Research identifies potential treatment target for infantile spasms syndrome

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics