Malignant News and Research

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Study unravels the link between chromosomal instability and cellular senescence

Chromosomal instability is a feature of solid tumours such as carcinoma. Likewise, cellular senescence is a process that is highly related to cellular ageing and its link to cancer is becoming increasingly clear. Scientists led by ICREA researcher Dr. Marco Milán at IRB Barcelona have revealed the link between chromosomal instability and cellular senescence.

7 Jul 2021

EORTC partners with Pierre Fabre to support patients with stage 2 melanoma

European Organisation for Research and Treatment of Cancer (EORTC) and Pierre Fabre today announced a strategic partnership in support of patients with resected Stage 2 BRAF-mutant melanoma.

29 Jun 2021

Research shines new light on deadly medulloblastoma metastases

With advances in medical science driving progress against childhood brain tumors, today three out of four young patients survive at least five years beyond diagnosis. However, the outcomes look grim when malignant cells spread, or metastasize.

29 Jun 2021

Moffitt awarded $10.2 million grant to investigate lung cancer metabolism

The National Cancer Institute has awarded the Lung Cancer Metabolism Working Group at Moffitt Cancer Center with a Research Program Project Grant (P01CA250984).

28 Jun 2021

Promising immunotherapy uses cancer-killing cells to destroy malignant tumors

Researchers at McMaster University have developed a promising new cancer immunotherapy that uses cancer-killing cells genetically engineered outside the body to find and destroy malignant tumors.

28 Jun 2021

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Oncotarget published "The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia" reported that polymorphisms of neurotransmitter metabolism genes were studied in patients with prostate cancer (PC) characterized by either reduced or extended serum prostate-specific antigen doubling time corresponding to unfavorable and favorable disease prognosis respectively.

28 Jun 2021

Study identifies the cell of origin of medulloblastoma

The study was conducted by an international collaboration involving the research team led by Luca Tiberi of the Armenise-Harvard Laboratory of Brain Cancer at the Department of Cellular, computational and integrative biology - Cibio of UniTrento, the Paris Brain Institute-Institut du Cerveau at Sorbonne Université in Paris, the Hopp Children´s Cancer Center (KiTZ) in Heidelberg, Germany, and Sapienza University in Rome.

24 Jun 2021

Researchers identify the origins of seven types of kidney cancer

The origins of seven types of kidney cancer, including several rare subtypes, have been identified by researchers at the Wellcome Sanger Institute, Great Ormond Street Hospital (GOSH), the Princess Máxima Center for Pediatric Oncology and Oncode Institute.

24 Jun 2021

Family history modifies the link between blood lipids and esophageal cancer risk

Several studies have associated blood lipids with different types of cancer like that of the food pipe or “esophagus,” but much remains to be understood, to apply this knowledge clinically.

24 Jun 2021

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

A new class of drugs that inhibits a "master switch" involved in the vast majority of cases of mantle cell lymphoma (MCL), a fatal subtype of non-Hodgkin's lymphoma, has been discovered by researchers at Mount Sinai.

22 Jun 2021

New antibody-drug conjugates also kill non-targeted neighboring tumor cells

How do you kill tumor cells that can't be targeted? Get their more susceptible neighbors to help.

22 Jun 2021

Researchers develop new therapeutic approach for treating acute myeloid leukemia

Leukemia stem cells are rare cells that can renew themselves while continuing to generate malignant cells known as leukemic blasts. These cells are difficult to eradicate using chemotherapy drugs and frequently lead to recurrence of leukemia.

22 Jun 2021

FDA approves oral pellets to treat children with venous thromboembolism

Today, the U.S. Food and Drug Administration approved Pradaxa (dabigatran etexilate) oral pellets to treat children 3 months to less than 12 years old with venous thromboembolism (a condition where blood clots form in the veins) directly after they have been treated with a blood thinner given by injection for at least five days.

21 Jun 2021

Imperial College Healthcare NHS Trust partners with Luscii to provide at-home monitoring platform for heart failure patients

Imperial College Healthcare NHS Trust is working with remote healthcare innovator, Luscii to provide a cutting-edge, at-home monitoring platform to support patients with heart failure.

21 Jun 2021

New platform can detect microRNA-205 with high sensitivity, excellent selectivity

In a paper published in NANO, a team of researchers from Jiangnan University, China have prepared a convenient sensing platform which can detect microRNA-205 (MiR-205) with high sensitivity and excellent selectivity using TpTta-COF nanosheet and fluorescent oligonucleotide probes.

18 Jun 2021

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Foresight Diagnostics, the emerging leader in blood-based lymphoma disease monitoring, announced today that clinical performance of its minimal residual disease (MRD) detection platform in diffuse large B-cell lymphoma (DLBCL) will be presented at the 16th International Conference on Malignant Lymphoma (ICML) on June 18-22, 2021.

18 Jun 2021

Study uncovers novel drug that effectively thwarts pancreatic tumors

Pancreatic cancer is an aggressive disease in which malignant cells form in the tissues of the pancreas, a long and flat gland located behind the stomach that helps with digestion and blood sugar regulation.

14 Jun 2021

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

A British man who rejected the standard of care to treat his brain cancer has lived with the typically fatal glioblastoma tumor growing very slowly after adopting a ketogenic diet, providing a case study that researchers say reflects the benefits of using the body's own metabolism to fight this particularly aggressive cancer instead of chemo and radiation therapy.

11 Jun 2021

Study provides treatment options for children with average risk medulloblastoma

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.

11 Jun 2021

Rice scientist wins NIH grant to model and analyze protein-ligand interactions in cancer research

Computer scientist Lydia Kavraki of Rice University's Brown School of Engineering has won a prestigious National Institutes of Health U01 grant to develop a new approach to model and analyze protein-ligand interactions in cancer research.

7 Jun 2021

Malignant News and Research

Study unravels the link between chromosomal instability and cellular senescence

EORTC partners with Pierre Fabre to support patients with stage 2 melanoma

Research shines new light on deadly medulloblastoma metastases

Moffitt awarded $10.2 million grant to investigate lung cancer metabolism

Promising immunotherapy uses cancer-killing cells to destroy malignant tumors

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Study identifies the cell of origin of medulloblastoma

Researchers identify the origins of seven types of kidney cancer

Family history modifies the link between blood lipids and esophageal cancer risk

Researchers discover new class of drugs that inhibits a 'master switch' in mantle cell lymphoma

New antibody-drug conjugates also kill non-targeted neighboring tumor cells

Researchers develop new therapeutic approach for treating acute myeloid leukemia

FDA approves oral pellets to treat children with venous thromboembolism

Imperial College Healthcare NHS Trust partners with Luscii to provide at-home monitoring platform for heart failure patients

New platform can detect microRNA-205 with high sensitivity, excellent selectivity

Foresight Diagnostics to demonstrate utility of PhasED-Seq technology at ICML meeting

Study uncovers novel drug that effectively thwarts pancreatic tumors

Ketogenic metabolic therapy could work synergistically with IDH1-mutant glioblastoma

Study provides treatment options for children with average risk medulloblastoma

Rice scientist wins NIH grant to model and analyze protein-ligand interactions in cancer research

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