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What the air you breathe may be doing to your brain

For years, the two patients had come to the Penn Memory Center at the University of Pennsylvania, where doctors and researchers follow people with cognitive impairment as they age, as well as a group with normal cognition.

12 Nov 2025

Shift Bioscience publishes improved metric calibration framework for robust genetic perturbation modeling using AI Virtual Cells

Shift Bioscience (Shift), a biotechnology company uncovering the biology of cell rejuvenation to end the morbidity and mortality of aging, today announced the release of new research detailing an improved framework for evaluating benchmark metric calibration in virtual cell models. U

From Shift Bioscience 11 Nov 2025

Evolocumab shows clear benefit in preventing first-time heart attacks and strokes

Adding the PCSK9 inhibitor evolocumab to standard lipid-lowering therapy significantly reduced first major cardiovascular events in adults with atherosclerosis or high-risk diabetes who had never had a heart attack or stroke. The 4.6-year study confirmed durable safety and benefit, supporting earlier, more intensive LDL cholesterol control.

11 Nov 2025

AI repurposes routine CT scans to detect hidden bone loss

Computed tomography (CT) scans of the chest, abdomen, and spine, taken originally to detect problems such as kidney stones or growths on the lungs, can be repurposed through artificial intelligence (AI) to catch signs of bone loss, a new study shows.

11 Nov 2025

Study examines medication adherence in high-risk, low-income populations

People with high blood pressure were twice as likely to take their blood pressure medication regularly when offered daily chances to win cash rewards, yet they did not achieve better blood pressure measurements than people who were not offered financial rewards, a new study shows.

11 Nov 2025

New data supports earlier use of evolocumab in high-risk diabetes

Adding the PCSK9 inhibitor evolocumab to a high-intensity, cholesterol-lowering regimen reduced the risk of a first major cardiovascular event among adults with atherosclerotic cardiovascular disease (ASCVD) or diabetes , according to a preliminary late-breaking science presentation today at the American Heart Association's Scientific Sessions 2025.

11 Nov 2025

Comparative study finds higher rates of adverse events with ticagrelor

One year of treatment with either of two strong blood-thinning medications—ticagrelor and prasugrel—by people with type 1 or type 2 diabetes who had a drug-eluting stent placed in their heart to treat coronary artery blockages did not offer the same level of benefit to prevent stent clotting, heart attacks, and bleeding complications, according to findings presented during a preliminary late-breaking science session during the American Heart Association's Scientific Sessions 2025 in New Orleans on November 10.

10 Nov 2025

Cash transfer programs improve health outcomes across low- and middle-income countries

Large-scale, government-led cash transfer programs drove significant improvements in health outcomes across low- and middle-income countries (LMICs), according to a major new study in The Lancet from researchers at the University of Pennsylvania Perelman School of Medicine.

10 Nov 2025

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

In a large real-world analysis across three U.S. healthcare databases, semaglutide and tirzepatide showed cardiovascular benefits consistent with randomized trials. Semaglutide lowered heart attack and stroke risk versus sitagliptin, while tirzepatide performed comparably to dulaglutide and semaglutide over one year.

10 Nov 2025

Long-term poverty and rising unsecured debt may increase risk of premature mortality

Adults who experience poverty-level family income-whether sustained or intermittent-over two decades spanning young to mid-adulthood face a significantly higher risk of dying prematurely than those who are never in poverty, according to new research led by Columbia University Mailman School of Public Health.

10 Nov 2025

Uppsala researchers develop Trojan horse approach for medulloblastoma treatment

The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available.

10 Nov 2025

Routine liquid biopsy testing could reduce late-stage cancer diagnoses

Routine screening is limited to only a few cancer types. New research indicates that routine liquid biopsy testing (multi-cancer early detection testing) could substantially reduce late-stage cancer diagnoses, allowing patients to receive treatment at earlier cancer stages, which are more likely to respond to interventions.

10 Nov 2025

One concussion can raise your car crash risk by nearly 50%

Research shows that concussions elevate the risk of motor vehicle crashes, particularly in the weeks following injury, necessitating enhanced safety measures.

10 Nov 2025

Death risk found to be six times higher among hospitalized patients with dyspnea

The risk of dying is six times higher among patients who become short of breath after being admitted to hospital, according to research published today (Monday) in ERJ Open Research. Patients who were in pain were not more likely to die.

10 Nov 2025

Beta-blockers offer no clinical benefit for myocardial infarction survivors with preserved cardiac function

A major analysis led by the Centro Nacional de Investigaciones Cardiovasculares (CNIC), in collaboration with international institutions, has pooled data from 17,801 myocardial infarction survivors with preserved cardiac function enrolled in five global clinical trials.

10 Nov 2025

Hypertensive disorders of pregnancy linked to increased risk of cardiovascular complications

A new study from researchers at Intermountain Health reveals that hypertensive disorders of pregnancy (HDP) significantly increase the risk of cardiovascular complications - including heart attack, stroke, heart failure, and death - within five years of giving birth.

10 Nov 2025

Expanding the waitlisting criteria for kidney transplantation could improve patient outcomes

The current kidney transplant waitlistingcriterion is based on a single measurement of kidney function (estimated glomerular filtration rate [eGFR] ≤20 ml/min/1.73m2) and does not consider an individual’s risk of progressing to kidney failure.

10 Nov 2025

New protocol developed for diagnosis and treatment of metformin-associated lactic acidosis

Metformin-associated lactic acidosis (MALA) is a rare but serious adverse effect of the diabetes drug metformin in which the body accumulates too much lactic acid. Investigators developed and tested a protocol for diagnosis and treatment of MALA.

10 Nov 2025

Coronary artery calcium score could help predict overall health and all-cause mortality

In a new study of more than 40,000 patients, researchers at Intermountain Health in Salt Lake City have found that patients who have no evidence of calcium in their coronary arteries are not only significantly less likely to die from heart conditions – including heart attacks and heart failure– but also are at reduced risk of death from non-cardiac medical conditions.

10 Nov 2025

Study shows record surge in reduced kidney function worldwide

Record numbers of men and women globally are now estimated to have reduced kidney function, a new study shows. Figures rose from 378 million people with the disease in 1990 to 788 million in 2023 as the world population grew and aged, making it for the first time a top 10 cause of death worldwide.

8 Nov 2025

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Mortality News and Research

What the air you breathe may be doing to your brain

Shift Bioscience publishes improved metric calibration framework for robust genetic perturbation modeling using AI Virtual Cells

Evolocumab shows clear benefit in preventing first-time heart attacks and strokes

AI repurposes routine CT scans to detect hidden bone loss

Study examines medication adherence in high-risk, low-income populations

New data supports earlier use of evolocumab in high-risk diabetes

Comparative study finds higher rates of adverse events with ticagrelor

Cash transfer programs improve health outcomes across low- and middle-income countries

Diabetes drugs semaglutide and tirzepatide show real-world heart benefits

Long-term poverty and rising unsecured debt may increase risk of premature mortality

Uppsala researchers develop Trojan horse approach for medulloblastoma treatment

Routine liquid biopsy testing could reduce late-stage cancer diagnoses

One concussion can raise your car crash risk by nearly 50%

Death risk found to be six times higher among hospitalized patients with dyspnea

Beta-blockers offer no clinical benefit for myocardial infarction survivors with preserved cardiac function

Hypertensive disorders of pregnancy linked to increased risk of cardiovascular complications

Expanding the waitlisting criteria for kidney transplantation could improve patient outcomes

New protocol developed for diagnosis and treatment of metformin-associated lactic acidosis

Coronary artery calcium score could help predict overall health and all-cause mortality

Study shows record surge in reduced kidney function worldwide

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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