Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Monitoring, treating kidney disease patients with blood pressure fluctuations may improve health: Study

Large fluctuations in blood pressure from day to day are a warning sign for African Americans with kidney disease, indicating that they may face an increased risk of dying prematurely.

16 Mar 2013

Study shows race and geographic area play important roles in patient with chronic kidney disease

Race and geographic area play important roles in determining whether a patient with chronic kidney disease receives optimal care before developing kidney failure, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

15 Mar 2013

Studies show protein semaphorin 3A helps detect acute kidney injury

A guidance cue that helps kidneys form may also be a red flag that they are in danger, researchers report.

13 Mar 2013

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

New research from Boston University School of Medicine (BUSM) reveals that B cells regulate obesity-associated inflammation and type 2 diabetes through two specific mechanisms.

13 Mar 2013

High-dose rosuvastatin reduces acute kidney injury caused by imaging dye in ACS patients

High doses of a popular cholesterol-lowering drug significantly reduced the rate of acute kidney injury caused by dye used in imaging in acute coronary syndrome patients who underwent a coronary procedure, according to research presented today at the American College of Cardiology's 62nd Annual Scientific Session.

12 Mar 2013

Viewpoints: 5 lies about entitlements; Obama's plans for Medicare still not clear; Generic drug makers need to be accountable

So here's a list with a bit more gravitas: The five biggest lies you're being told about entitlement programs. Never mind that the very word "entitlement" is a lie. Social Security and Medicare got that name because workers became "entitled" to those benefits by paying into the system. In recent years, however, the term has become distorted to signify benefits people are entitled to without earning them. Leaving that whopper aside, here are the top five.

12 Mar 2013

IV iron dextran alternative to oral iron for anemia in nondialysis CKD

Treatment with intravenous low-molecular-weight iron dextran seems to be an effective alternative for patients with nondialysis chronic kidney disease who remain anemic despite receiving oral iron and erythropoiesis-stimulating agents.

8 Mar 2013

Failure to use aspirin before angioplasty increases death rate

Despite recommendations from leading medical groups, a surprising number of patients are not given aspirin before artery-clearing coronary angioplasty and stenting, and those patients have a significantly higher in-hospital death rate, according to research from a Michigan network being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Telemedicine use appears to help urban communities achieve blood pressure goals

Using a telemedicine system to engage people in underserved, urban communities to measure and report their blood pressure remotely-outside of the doctor's office-appears to help them achieve blood pressure goals and improve adherence to lifestyle changes and medication recommendations, according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Minor weight loss may increase risk of cardiac events among patients implanted with CRT-D

Even minor weight loss is associated with worse health outcomes among patients implanted with a certain type of defibrillator known as cardiac resynchronization therapy with defibrillator (CRT-D), according to research being presented at the American College of Cardiology's 62nd Annual Scientific Session.

8 Mar 2013

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

Kidney failure affects 25 million individuals in the U.S. and many more throughout the world. Loss of kidney function means the majority of these patients must undergo dialysis treatments to remove excess fluids and waste products. Although dialysis therapy coupled with medication has improved the life expectancy for people with kidney failure, for unknown reasons, patients' risk of sudden heart failure and death remains 10 to 20 times greater than average.

7 Mar 2013

FDA accepts AMAG’s Feraheme sNDA for review

AMAG Pharmaceuticals, Inc. today announced that the United States Food and Drug Administration (FDA) has accepted for review the company's supplemental new drug application (sNDA) for Feraheme (ferumoxytol) Injection for Intravenous (IV) use, which was submitted to the FDA in December 2012.

6 Mar 2013

People with variations in FTO gene could be at increased risk of melanoma

The research shows that people with particular variations in a stretch of DNA within the FTO gene, called intron 8, could be at greater risk of developing melanoma.

5 Mar 2013

OPKO Health acquires Cytochroma

OPKO Health, Inc. announced that it has completed the acquisition of Cytochroma Inc. Cytochroma's lead products include CTAP101 Capsules, a vitamin D prohormone to treat secondary hyperparathyroidism (SHPT) in patients with stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency, and Fermagate Tablets, a new and potent non-absorbed phosphate binder to treat hyperphosphatemia in CKD patients on chronic hemodialysis.

4 Mar 2013

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Systemic lupus erythematosus (SLE) is disease in which the immune system mistakenly attacks healthy tissues, resulting in inflammation and tissue damage. Current treatments are focused on suppression of the immune system, but these therapies can leave patients vulnerable to infection.

2 Mar 2013

Urinary cystatin C prognostic marker in acute kidney injury

Urinary cystatin C level may be a useful biomarker for discriminating between prerenal and intrinsic acute kidney injury, report researchers.

1 Mar 2013

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

New insight into grape seed extract as a therapeutic and preventative measure to fight obesity-induced kidney damage is presented in a new study. Grape seed and skin extract (GSSE) is known to contain powerful antioxidants.

1 Mar 2013

CellAegis Devices to use autoRIC Device for Chronic Remote Ischemic Conditioning

CellAegis Devices, Inc., announced today that it has received an Investigational Testing Approval from Health Canada that allows the initiation of clinical testing in Canada of the Company's autoRIC Device for Chronic Remote Ischemic Conditioning (CRIC).

27 Feb 2013

Anemia medication recall could affect thousands of kidney-disease patients

The recall comes as a sharp blow to Affymax, a small biotechnology firm based in Palo Alto, Calif., that developed Omontys and has no other late-stage drugs in its pipeline.

26 Feb 2013

Catheters may increase risk of death, infections and cardiovascular events in dialysis patients

Dialysis patients using catheters to access the blood have the highest risks for death, infections, and cardiovascular events compared with patients using other types of vascular access, according to an analysis appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

22 Feb 2013

Nephropathy News and Research

Further Reading

Monitoring, treating kidney disease patients with blood pressure fluctuations may improve health: Study

Study shows race and geographic area play important roles in patient with chronic kidney disease

Studies show protein semaphorin 3A helps detect acute kidney injury

B cells regulate obesity-associated inflammation and T2D through two specific mechanisms

High-dose rosuvastatin reduces acute kidney injury caused by imaging dye in ACS patients

Viewpoints: 5 lies about entitlements; Obama's plans for Medicare still not clear; Generic drug makers need to be accountable

IV iron dextran alternative to oral iron for anemia in nondialysis CKD

Failure to use aspirin before angioplasty increases death rate

Telemedicine use appears to help urban communities achieve blood pressure goals

Minor weight loss may increase risk of cardiac events among patients implanted with CRT-D

Carbamylation contributes to heart disease risk among patients with CKD undergoing dialysis

FDA accepts AMAG’s Feraheme sNDA for review

People with variations in FTO gene could be at increased risk of melanoma

OPKO Health acquires Cytochroma

Nanogel-based delivery of mycophenolic acid ameliorates systemic lupus erythematosus

Urinary cystatin C prognostic marker in acute kidney injury

Study links grape seed and skin extracts with high-fat-diet-induced renal disease

CellAegis Devices to use autoRIC Device for Chronic Remote Ischemic Conditioning

Anemia medication recall could affect thousands of kidney-disease patients

Catheters may increase risk of death, infections and cardiovascular events in dialysis patients

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