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Mpox virus from Clade 2b is the least virulent strain according to new study

Researchers used the CAST/EiJ mouse model to test whether genetic differences between clades 1, 2a, and 2b of the monkeypox virus contribute to changes in transmission and virulence of the disease.

5 Dec 2022

Study explores histopathological, serological, and clinical characteristics of PASC in patients with mild COVID-19

Researchers investigated the clinical, histopathological, imaging, and serological characteristics of post-acute sequelae of coronavirus disease 2019 (COVID-19) (PASC) in patients with mild COVID-19.

5 Dec 2022

Study provides understanding of SARS-CoV-2 pulmonary infection long-term effects at the microanatomical, cellular, and molecular level

Researchers evaluated compositional and structural pulmonary alterations in PASC tissues.

5 Dec 2022

Impact of COVID-19 booster vaccination and breakthrough infection

Researchers assessed the protection elicited after a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) booster vaccination or a breakthrough infection against SARS-CoV-2 Omicron variant infection.

5 Dec 2022

Study estimates the epidemiological impact of a COVID-19 testing-related incident at a surge laboratory in the UK

Researchers investigated the epidemiological impact of an incident at a laboratory in the UK.

5 Dec 2022

Researchers uncover the host protease CAPN2 as a novel host factor that aids the infection of SARS-CoV-2

Researchers investigated the potential of the CAPN2 molecule as a therapeutic target against SARS-CoV-2.

5 Dec 2022

SARS-CoV-2 Omicron infections pose long-COVID risks despite reduced severity

researchers compared the post-coronavirus disease complaints and symptoms in individuals infected with the SARS-CoV-2 Omicron variant with those in individuals with Delta variant infections to understand whether the long-term complaints after Omicron infections are similar to those in infections with other SARS-CoV-2 variants.

2 Dec 2022

The prevalence and risk factors of pediatric post-COVID in a population-based sample

Researchers compared seropositive and seronegative children between the ages of six months and 17 years to assess the risk factors and prevalence of persistent symptoms of post-COVID syndrome.

2 Dec 2022

Risk factor assessment for the development of severe SARS-CoV-2 breakthrough infections

researchers evaluated the severity of breakthrough SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infections and the risk factors associated with severity among individuals vaccinated for coronavirus disease 2019 (COVID-19) in Sousse, Tunisia.

1 Dec 2022

Are medical masks non-inferior to N95 respirators to prevent COVID-19 in health care workers providing routine care?

Researchers determined whether medical masks were non-inferior to N95 respirators in preventing a SARS-CoV-2)infection in healthcare workers.

1 Dec 2022

SARS-CoV-2 can cause hyperglycemia in cats

In a recent study published in The Journal of Infectious Diseases, researchers explored the association between severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and hyperglycemia in cats.

30 Nov 2022

Phase 2/3 clinical trial shows that Clover’s vaccine candidate reduces household transmission of SARS-CoV-2

Clover Biopharmaceuticals, Ltd., a global clinical-stage biotechnology company developing novel vaccines and biologic therapeutics, and the International Vaccine Institute, an international nonprofit organization devoted to providing vaccines critical to global public health and based in Seoul, Korea, today announced that Clinical Infectious Diseases has published additional data from SPECTRA, a global Phase 2/3 clinical trial, that showed vaccination with SCB-2019 (CpG 1018/Alum) reduced the risk of transmitting SARS-CoV-2 infection to household members, compared to placebo participants.

30 Nov 2022

The effect of evolutionary changes in prolonged SARS-CoV-2 infection in an immunosuppressed individual due to advanced HIV

Researchers assessed the impact of SARS-CoV-2 infection on cell death and fusion in an immunocompromised host.

30 Nov 2022

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.

30 Nov 2022

New evidence of mpox virus transmission before onset of symptoms

Researchers extensively followed-up high-risk contacts of clade IIb mpox (MPX) virus (MPXV)-infected patients to evaluate the risk of MPX after MPXV exposure and to characterize early MPXV infections.

30 Nov 2022

CSU engineers introduce a better way to perform mosquito-tracking for disease applications

West Nile, Zika, dengue and malaria are all diseases spread by bites from infected mosquitoes. To track the threat of such diseases over large populations, scientists need to know where the mosquitoes are, where they've been, and where they might go.

30 Nov 2022

SARS-CoV-2 RNA found to be present in various environmental surface samples

Researchers conducted environmental surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA).

29 Nov 2022

How do COVID-19 outcomes vary by race and gender?

Researchers investigated the variations in coronavirus disease 2019 (COVID-19) testing and severe outcomes according to race, ethnicity, and gender.

29 Nov 2022

Small CDC study looks at SARS-CoV-2 viral shedding in vaccinated and unvaccinated

A new Centers for Disease Control and Prevention (CDC) study published in the Vaccine journal aimed to analyze the viral shedding and conversion timeline of SARS-CoV-2 infected people from exposure to infection and onset of symptoms during a period of Delta outbreak in a federal prison in Texas.

28 Nov 2022

Large COVID vaccination study found that thrombosis and thrombocytopenia are very rare complications

Researchers determine the rates of thrombosis, thrombocytopenia, and thrombosis with thrombocytopenia following COVID-19 vaccination and infection.

28 Nov 2022

Polymerase News and Research

Mpox virus from Clade 2b is the least virulent strain according to new study

Study explores histopathological, serological, and clinical characteristics of PASC in patients with mild COVID-19

Study provides understanding of SARS-CoV-2 pulmonary infection long-term effects at the microanatomical, cellular, and molecular level

Impact of COVID-19 booster vaccination and breakthrough infection

Study estimates the epidemiological impact of a COVID-19 testing-related incident at a surge laboratory in the UK

Researchers uncover the host protease CAPN2 as a novel host factor that aids the infection of SARS-CoV-2

SARS-CoV-2 Omicron infections pose long-COVID risks despite reduced severity

The prevalence and risk factors of pediatric post-COVID in a population-based sample

Risk factor assessment for the development of severe SARS-CoV-2 breakthrough infections

Are medical masks non-inferior to N95 respirators to prevent COVID-19 in health care workers providing routine care?

SARS-CoV-2 can cause hyperglycemia in cats

Phase 2/3 clinical trial shows that Clover’s vaccine candidate reduces household transmission of SARS-CoV-2

The effect of evolutionary changes in prolonged SARS-CoV-2 infection in an immunosuppressed individual due to advanced HIV

Scientists discover how an enzyme involved in DNA repair becomes vital to tumor survival

New evidence of mpox virus transmission before onset of symptoms

CSU engineers introduce a better way to perform mosquito-tracking for disease applications

SARS-CoV-2 RNA found to be present in various environmental surface samples

How do COVID-19 outcomes vary by race and gender?

Small CDC study looks at SARS-CoV-2 viral shedding in vaccinated and unvaccinated

Large COVID vaccination study found that thrombosis and thrombocytopenia are very rare complications

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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