Rheumatology News and Research

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Rheumatology is a sub-specialty in internal medicine and pediatrics, devoted to the diagnosis and therapy of rheumatic diseases. Rheumatologists mainly deal with clinical problems involving joints, soft tissues and allied conditions of connective tissues.

Physical workload could increase odds of developing RA

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that prolonged repetitive physical workload increases the risk of developing rheumatoid arthritis (RA).

13 Jun 2016

Researchers find link between specific genetic pathway and development of mouth ulcers in lupus patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed for the first time an association between a specific genetic pathway and the development of mouth ulcers in patients with Systemic Lupus Erythematosus (SLE).

13 Jun 2016

Study opens up possibility of developing potential hormone therapies for SSc skin disease

The results of a study presented today at the European League Against Rheumatism Annual Congress showed for the first time a beneficial effect of oestrogens in experimental models of skin fibrosis that are representative of the disease process in systemic sclerosis (SSc).

13 Jun 2016

Findings may help explain why rheumatoid arthritis drugs vary in effect

Researchers at the University of California San Diego School of Medicine, with colleagues in Pennsylvania and China, report that not only are there distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint-specific differences in RA.

12 Jun 2016

Study finds link between depression, disease activity and disability in adolescents with JIA

European League Against Rheumatism Annual Congress confirmed a clear association between depression symptom severity and the level of disease activity and disability in adolescent patients with juvenile inflammatory arthritis.

12 Jun 2016

Smoking, obesity lower chances of achieving sustained remission in early RA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that the likelihood of achieving sustained remission in early rheumatoid arthritis (RA) is significantly lower in patients who smoke and who are obese.

10 Jun 2016

Study shows rheumatologists underestimate disease severity in OA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed patients with osteoarthritis (OA) are more likely to have the impact of their condition underestimated by rheumatologists than patients with Rheumatoid Arthritis (RA).

10 Jun 2016

New PsA-comorbidity index may help identify patients at risk of hospitalisation and premature death

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that a newly developed method of evaluating the impact of different comorbidities in patients with Psoriatic Arthritis (PsA) can be used to prospectively identify those PsA patients at greater risk of hospitalisation and premature death.

10 Jun 2016

Women with SLE may have increased cervical cancer risk

The results of a study presented today at the European League Against Rheumatism Annual Congress found a doubled risk of pre-malignant cervical changes, and potentially also an increased risk of cervical cancer, among women with Systemic Lupus Erythematosus (SLE) compared to the general female population.

10 Jun 2016

Implantable loop recorder can help diagnose heart rhythm abnormalities in SSc patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that use of an easy to insert heart monitor in patients with systemic sclerosis (SSc) and no known heart disease enables early detection and treatment of potentially fatal cardiac arrhythmias.

10 Jun 2016

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that tiny particles made of a biodegradable polymer (BNPs -- biodegradable polymer nanoparticles) have the potential to enable early detection and efficient long-term treatment of rheumatoid arthritis (RA), with minimal side effects.

10 Jun 2016

Type 1 diabetes occurs more frequently in patients with JIA

The results of a study involving more than 9,000 patients, presented today at the European League Against Rheumatism Annual Congress showed that Type 1 diabetes occurs significantly more frequently in patients with Juvenile Inflammatory Arthritis (JIA) than in the general population.

10 Jun 2016

Anti-CPP presence in bloodstream of RA patients correlates with drug response

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that the presence of an antibody (anti-CPP ) in the bloodstream of patients with rheumatoid arthritis (RA) correlates with response to different drug treatments.

10 Jun 2016

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that when antibodies develop in response to the biological treatment Remicade (infliximab), they also cross-react with the biosimilar of infliximab (CT-P13: Inflectra or Remsima).

10 Jun 2016

Air pollution exposure may have direct role in triggering lupus among children and adolescents

The results of a study presented today at the European League Against Rheumatism Annual Congress show for the first time that an individual's exposure to air pollution may have a direct role in triggering disease activity as well as airway inflammation in children and adolescents with Systemic Lupus Erythematosus (SLE).

10 Jun 2016

Reduced RV functional reserve may explain poor SSc-PAH outcomes

Patients who develop pulmonary arterial hypertension as a consequence of systemic sclerosis have poorer right ventricular functional reserve than those with idiopathic disease, research published in Circulation shows.

9 Jun 2016

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

While hospitalizations related to rheumatoid arthritis have dropped considerably over the past two decades, hospitalizations primarily associated with gout have increased dramatically.

8 Jun 2016

Maternal immune dysfunction linked to risk of autism with intellectual disability in children

Pregnant women with higher levels of inflammatory cytokines and chemokines, proteins that control communication between cells of the immune system, may be at significantly greater risk of having a child with autism combined with intellectual disability, researchers with the UC Davis MIND Institute have found.

8 Jun 2016

UK-wide study reveals AOD prescription rates for women decrease in last 10 years

A UK-wide study looking at the prescribing of anti-osteoporotic drugs (AOD) to people aged 50 years or above has found that, since 2006, AOD prescription rates for women have decreased and rates for men have levelled off, despite a growing elderly population and associated fracture risks.

19 May 2016

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Researchers at Beth Israel Deaconess Medical Center have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus.

17 May 2016

Rheumatology News and Research

Further Reading

Physical workload could increase odds of developing RA

Researchers find link between specific genetic pathway and development of mouth ulcers in lupus patients

Study opens up possibility of developing potential hormone therapies for SSc skin disease

Findings may help explain why rheumatoid arthritis drugs vary in effect

Study finds link between depression, disease activity and disability in adolescents with JIA

Smoking, obesity lower chances of achieving sustained remission in early RA patients

Study shows rheumatologists underestimate disease severity in OA patients

New PsA-comorbidity index may help identify patients at risk of hospitalisation and premature death

Women with SLE may have increased cervical cancer risk

Implantable loop recorder can help diagnose heart rhythm abnormalities in SSc patients

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

Type 1 diabetes occurs more frequently in patients with JIA

Anti-CPP presence in bloodstream of RA patients correlates with drug response

Antibody-positive patients treated with infliximab less likely to benefit from infliximab biosimilar

Air pollution exposure may have direct role in triggering lupus among children and adolescents

Reduced RV functional reserve may explain poor SSc-PAH outcomes

Study finds differences in hospitalization trends for gout and rheumatoid arthritis

Maternal immune dysfunction linked to risk of autism with intellectual disability in children

UK-wide study reveals AOD prescription rates for women decrease in last 10 years

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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