Signaling Pathway News and Research

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Lipid aids healing of scratches on the cornea

A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.

26 Mar 2020

Researchers uncover molecular link between trans fats and variety of disorders

Tohoku University researchers in Japan have uncovered a molecular link between some trans fats and a variety of disorders, including cardiovascular and neurodegenerative diseases.

25 Mar 2020

Research demonstrates control mechanism of force-induced cell-to-cell attachment

Using the amphibian Xenopus laevis as a model, Drs. Noriyuki Kinoshita and Naoto Ueno from the National Institute for Basic Biology, Japan and Dr. Ileana Cristea from Princeton University, USA have demonstrated that physical forces, such as centrifugal force, enhance cell-to-cell attachment and increase the stiffness of embryonic tissues as a result of force-induced cell shape change.

18 Mar 2020

Drug from scorpion venom could offer hope for children with fetal alcohol spectrum disorder

A research team led by Children's National Hospital faculty was able to "rescue" a pre-clinical model of fetal alcohol spectrum disorder in juvenile models, reversing motor skill deficits with the help of a novel drug derived from scorpion venom.

18 Mar 2020

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

An important biological mechanism that is thought to protect brain cells from neurodegenerative diseases such as Alzheimer's and Parkinson's may also be involved in regulating sleep, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

12 Mar 2020

Gut bacteria can accumulate in tumors and improve effectiveness of cancer immunotherapy

Researchers at the University of Texas Southwestern Medical Center and University of Chicago have discovered that bacteria that usually live in the gut can accumulate in tumors and improve the effectiveness of immunotherapy in mice.

10 Mar 2020

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Could the response to cancer immunotherapy depend on bacteria that originate in the gut and travel to the tumor?

7 Mar 2020

Study provides new insight into neurofibromin-deficient ER+ breast cancer

An international team of researchers led by scientists at Baylor College of Medicine has new insights into the function of neurofibromin, a tumor suppressor produced by the NF1 gene.

5 Mar 2020

Study identifies a protein and signaling pathway that may contribute to sudden cardiac death

By studying the sick hearts removed from four patients undergoing heart transplants, researchers have identified a protein and a signaling pathway that may contribute to sudden death in an inherited form of heart disease.

3 Mar 2020

Major investment can help improve technology aimed at turning bad fat to good fat

A significant investment from a Purdue University alumnus and his wife will help further develop technology aimed at treating obesity and diabetes by turning bad fat into good fat inside the body.

28 Feb 2020

New study expands the knowledge on tumor-suppressor role of HERC proteins

The RAF protein could be a therapeutical target to treat the tumor growth in regulated pathways by the p38 protein, according to a new study published in the journal Scientific Reports by a team of experts of the Faculty of Medicine and Health Sciences of the University of Barcelona and the Bellvitge Institute for Biomedical Research.

20 Feb 2020

UCLA researchers identify new molecule that promotes airway health

A molecule identified by UCLA researchers helps maintain a healthy balance of cells in airway and lung tissue.

18 Feb 2020

Breakthrough discovery could open up new treatments for some blood cancers

Reversing runaway inflammation in the bone marrow could lead to major breakthroughs in treatments for some blood cancers, according to a new publication by scientists at Hackensack Meridian Health's Center for Discovery and Innovation.

16 Feb 2020

Study provides a detailed molecular snapshot of endometrial cancer

A study published Feb. 13 in Cell provides an unprecedented look at the dozens of molecular steps that occur to bring about endometrial cancer, commonly known as uterine cancer.

14 Feb 2020

Molecular study defines the contributions of key genes, proteins to endometrial cancer

The most comprehensive molecular study of endometrial cancer to date has further defined the contributions of key genes and proteins to the disease, say its authors.

13 Feb 2020

Metformin could help leaky gut

A team of researchers from University of California, San Diego, have successfully used gut organoids in their lab to show the effects of medications to treat conditions such as “leaky gut”. The study was titled, “The stress polarity signaling (SPS) pathway serves as a marker and a target in the leaky gut barrier: implications in aging and cancer,” and was published in the journal Life Science Alliance today.

10 Feb 2020

Signaling Pathway News and Research

Lipid aids healing of scratches on the cornea

Researchers uncover molecular link between trans fats and variety of disorders

Research demonstrates control mechanism of force-induced cell-to-cell attachment

Drug from scorpion venom could offer hope for children with fetal alcohol spectrum disorder

Protective brain-cell housekeeping mechanism may also be involved in regulating sleep

Gut bacteria can accumulate in tumors and improve effectiveness of cancer immunotherapy

Gut bacteria can boost effectiveness of cancer immunotherapy, mice study suggests

Study provides new insight into neurofibromin-deficient ER+ breast cancer

Study identifies a protein and signaling pathway that may contribute to sudden cardiac death

Major investment can help improve technology aimed at turning bad fat to good fat

New study expands the knowledge on tumor-suppressor role of HERC proteins

UCLA researchers identify new molecule that promotes airway health

Breakthrough discovery could open up new treatments for some blood cancers

Study provides a detailed molecular snapshot of endometrial cancer

Molecular study defines the contributions of key genes, proteins to endometrial cancer

Metformin could help leaky gut

Researchers simulate leaky gut conditions using 3D models of human intestines

Cedars-Sinai researchers to study role of fat in promoting cancer spread to liver

Heart muscle cells of zebrafish change their metabolism during heart regeneration

Yale researchers find way to reverse type-2 diabetes and liver fibrosis in mice

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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