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Sequential and combination chemotherapy equally effective in treating advanced colorectal cancer

Many patients with incurable advanced colorectal cancer could be offered a more gentle treatment strategy starting with a single chemotherapy drug, as an alternative to current standard initial combination chemotherapy, without compromising their survival.

16 Jul 2007

Discovery of one important function of junk DNA

Scientists have only recently begun to speculate that what's referred to as junk DNA , the 96 percent of the human genome that doesn't encode for proteins and previously seemed to have no useful purpose , is present in the genome for an important reason.

13 Jul 2007

Genes play a large role in sour taste perception

Scientists at the Monell Chemical Senses Center report that genes play a large role in determining individual differences in sour taste perception.

12 Jul 2007

Next generation painkillers

Scientists studying one of nature's simplest organisms have helped to unravel the structure of a key molecule that controls pain in humans.

From The University of Manchester 12 Jul 2007

First mouse model of lung transplantation

Lung transplants have been performed successfully for more than 20 years in humans but never before in mice – until now.

12 Jul 2007

A genetically informed study of the intergenerational transmission of marital instability

The first study to examine genetics as a culprit in the higher-than-usual divorce rate among children of divorced parents found that the parents' divorce itself, not genes or even problems such as parental substance abuse or delinquency, played a key role in the failed unions.

12 Jul 2007

For older women HRT a risky option

According to an international study older women should not take Hormone Replacement Therapy (HRT).

12 Jul 2007

No benefit from HRT for older women

New evidence confirms that hormone replacement therapy (HRT) should not be prescribed to older women who are many years past the menopause. The treatment will not help prevent chronic conditions such as heart disease in these women.

11 Jul 2007

Cancer-causing enzyme could be stopped

Scientists from the MRC's Laboratory of Molecular Biology (LMB) and the Albert Einstein College of Medicine have discovered a way to stop an enzyme responsible for many cancers.

11 Jul 2007

Baxter presents findings from the ADAPT study

Baxter Healthcare Corporation has announced the presentation of findings from the ADAPT (Analysis of Data from ADVATE Prospective Trials) study program database showing a statistically significant relationship between the duration of time spent with factor VIII blood levels below one international unit per deciliter (1 IU/dL, one percent of normal factor VIII level) and an increase in the annual bleed rate in people with hemophilia A.

11 Jul 2007

Scientists identify two brain networks in Parkinson's

The disease that causes tremors, rigidity and slowed movements in a million Americans also targets another brain network that regulates cognitive thought and the ability to carry out everyday tasks.

10 Jul 2007

Scientists discover first common bowel cancer gene

Cancer Research UK funded scientists have for the first time identified a common genetic variant that can increase a person's risk of developing bowel cancer. Their findings appear in two papers published online in Nature Genetics.

9 Jul 2007

Discovery of enzyme critical in DNA replication

In this week's issue of Science, researchers from the National Institute of Environmental Health Sciences (NIEHS) and Umea University in Sweden report an important discovery about a critical new role that an enzyme called DNA polymerase epsilon plays in replicating DNA in higher organisms such as yeast and perhaps even humans.

9 Jul 2007

NanoSIMS instrument clarifies nutrient cycle

Scientists at the University of Southern California have applied a nanoscale imaging method to a biological system, helping to clear up an old puzzle of the global carbon and nitrogen cycle.

9 Jul 2007

Genome detectives reveal gene suspect for bowel cancer

Scientists in Britain have identified a gene they say increases the risk of bowel cancer by 20%.

8 Jul 2007

Investigating life in extreme environments

From the deepest seafloor to the highest mountain, from the hottest region to the cold Antarctic plateau, environments labelled as extreme are numerous on Earth and they present a wide variety of features and characteristics.

5 Jul 2007

Myeloperoxidase protein provides clues to heart attacks in healthy people

We've all wondered how a seemingly healthy person can actually be at high risk for heart disease or a heart attack.

4 Jul 2007

Scientists tackle deadly hospital superbugs

It infiltrates hospitals as microscopic spores. Its defences are so strong it can resist most antibiotics. And it kills three times as many people every year as MRSA. But scientists at The University of Nottingham are amassing an arsenal of weapons in preparation for counter offensive against the most deadly of hospital superbugs.

4 Jul 2007

War and forced displacement have reduced the transmission of HIV in sub-Saharan Africa

Conflict, forced displacement, and wide-scale rape have not increased the prevalence of HIV in sub-Saharan Africa, conclude the authors of an Article in this week's issue of The Lancet.

29 Jun 2007

New type of mouse embryonic stem cell discovered

Scientists have discovered a new type of mouse embryonic stem cell that is the closest counterpart yet to human embryonic stem (ES) cells, the National Institutes of Health (NIH) have announced.

28 Jun 2007