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Key findings may have broad implications for future scleroderma therapy

The Scleroderma Research Foundation today said that researchers at The Johns Hopkins University working in a novel mouse model of Stiff Skin Syndrome have made key discoveries that may have broad implications for future scleroderma therapy.

10 Oct 2013

Active Biotech And Hutchison China Meditech Get Rewarded

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9 Oct 2013

Understanding the biological players in clot formation could lead to new thrombotic therapies

Ulhas Naik, professor of biological sciences and director of the Delaware Cardiovascular Research Center, pores over laboratory data on his computer, even during breakfast most mornings. He is on a quest to tease out the roles that various blood components play in the formation of clots.

9 Oct 2013

New method for improving cord blood transplant success

Starting with a discovery in zebrafish in 2007, Harvard Stem Cell Institute researchers have published initial results of a Phase Ib human clinical trial of a therapeutic that has the potential to improve the success of blood stem cell transplantation.

9 Oct 2013

Study shows nitric oxide can promote and inhibit lateral root formation

The structure and plasticity of root systems play an important role in determining the growth and yield of crop plants, and understanding how environmental and biological factors affect root structure is of key importance for plant scientists-particularly agricultural scientists.

9 Oct 2013

CNIO researcher identifies new molecular mechanism that regulates genome stability, cell proliferation

Cell division is an essential process for the development of an organism. This process, however, can cause tumour growth when it stops working properly. Tumour cells accumulate alterations in their genetic material, and this makes them divide in an uncontrolled fashion, thus encouraging growth of the tumour.

9 Oct 2013

Study: Distinct behavior of proteins reflects common biochemical principles

Researchers from Case Western Reserve University School of Medicine have found unexpected similarities between proteins that were thought to be fundamentally different.

9 Oct 2013

Alkermes completes patient enrollment in phase 3 study of aripiprazole lauroxil in schizophrenia patients

Alkermes plc (NASDAQ: ALKS) today announced completion of patient enrollment in the pivotal, multinational phase 3 study evaluating aripiprazole lauroxil in patients with schizophrenia.

9 Oct 2013

MNK-795 for acute pain management: an interview with Dr Lynn Webster

MNK-795 is a product in development that is intended to be used for acute pain. It has some unique properties. First, it is an extended release formulation, meaning that it’s going to last more than three to four hours. It was studied to be dosed once every 12 hours, and that is unique for an acute pain formulation.

8 Oct 2013

LSTM professor wins Universal Biotech Innovation Prize 2013 for Hexagard

Professor Richard Pleass has won the Prix de l’Innovation 2013, also known as the Universal Biotech Innovation Prize 2013.

8 Oct 2013

Researchers examine how JC polyomavirus enters into cells

For more than a decade the research group of Brown University Professor Walter Atwood has doggedly pursued the workings of the JC polyomavirus, which causes a disease called PML that fatally degrades the central nervous system of patients with weakened immune systems.

8 Oct 2013

PET scan shows promise in predicting patients with inoperable lung cancer

Advanced imaging with Positron Emission Tomography (PET) scan shows great promise in predicting which patients with inoperable lung cancer have more aggressive tumors and need additional treatment following standard chemotherapy/radiation therapy, according to new research recently published online in the Journal of Clinical Oncology.

8 Oct 2013

GABA inverse agonist restores learning, memory performances in cognitively-impaired DS mice

A selective GABA inverse agonist has restored cognitive function in a mouse model of Down's syndrome (DS) and has the potential to benefit humans, French researchers have revealed.

8 Oct 2013

Scientists devised technique to make antibody-drug conjugates, basis of new therapies

Chemists at The Scripps Research Institute (TSRI) have devised a new technique for connecting drug molecules to antibodies to make advanced therapies.

8 Oct 2013

Smoking during pregnancy may affect child’s immune system on molecular level

The Leipzig Helmholtz Center for Environmental Research has gained new insights on the influence of tobacco smoke in utero. For the first time, it could be demonstrated with smoking pregnant women and their children, how exposure to tobacco smoke affects the development of human immune system on molecular level.

8 Oct 2013

Researchers discover how cancer development molecule maintains its genome integrity

University of Montreal researchers have discovered how telomerase, a molecule essential for cancer development, is directed to structures on our genome called telomeres in order to maintain its integrity and in turn, the integrity of the genome.

7 Oct 2013

Anti-inflammatory mechanism leads to development of oral medications for atherosclerosis, IBS

Research led by Charles Nichols, PhD, Associate Professor of Pharmacology at LSU Health Sciences Center New Orleans, describes a powerful new anti-inflammatory mechanism that could lead to the development of new oral medications for atherosclerosis and inflammatory bowel disorders (IBS).

7 Oct 2013

Researchers create catalyst that alters chemical profiles of numerous types of small molecules

Researchers report that they have created a man-made catalyst that is an "enzyme mimic." Unlike most enzymes, which act on a single target, the new catalyst can alter the chemical profiles of numerous types of small molecules.

7 Oct 2013

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

Investigators at The Feinstein Institute for Medical Research have discovered a protein in the human body that can trigger and mediate inflammation in patients suffering from hemorrhage and sepsis. The findings were published in the online version of Nature Medicine on October 6, 2013.

7 Oct 2013

$Binge drinking can impair healing process following bone fracture$

Binge drinking can impair healing process following bone fracture

Physicians have long observed that binge drinking can significantly impair the healing process following a bone fracture.

7 Oct 2013

Molecule News and Research

Key findings may have broad implications for future scleroderma therapy

Active Biotech And Hutchison China Meditech Get Rewarded

Understanding the biological players in clot formation could lead to new thrombotic therapies

New method for improving cord blood transplant success

Study shows nitric oxide can promote and inhibit lateral root formation

CNIO researcher identifies new molecular mechanism that regulates genome stability, cell proliferation

Study: Distinct behavior of proteins reflects common biochemical principles

Alkermes completes patient enrollment in phase 3 study of aripiprazole lauroxil in schizophrenia patients

MNK-795 for acute pain management: an interview with Dr Lynn Webster

LSTM professor wins Universal Biotech Innovation Prize 2013 for Hexagard

Researchers examine how JC polyomavirus enters into cells

PET scan shows promise in predicting patients with inoperable lung cancer

GABA inverse agonist restores learning, memory performances in cognitively-impaired DS mice

Scientists devised technique to make antibody-drug conjugates, basis of new therapies

Smoking during pregnancy may affect child’s immune system on molecular level

Researchers discover how cancer development molecule maintains its genome integrity

Anti-inflammatory mechanism leads to development of oral medications for atherosclerosis, IBS

Researchers create catalyst that alters chemical profiles of numerous types of small molecules

Researchers identify protein that triggers inflammation in patients with hemorrhage, sepsis

Binge drinking can impair healing process following bone fracture

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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