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University of Kentucky begins world’s first clinical trial for LATE

The motivation driving the work of Pete Nelson, M.D., Ph.D., is personal. His grandmother, Sylvia Becker, died with Alzheimer's disease, and he says his mother then grew terrified of developing the disease.

17 Mar 2022

People with elevated blood pressure upon standing more likely to have risk for cardiovascular events

Among young and middle-aged adults with high blood pressure, a substantial rise in blood pressure upon standing may identify those with a higher risk of serious cardiovascular events, such as heart attack and stroke, according to new research published today in the American Heart Association's peer-reviewed journal Hypertension.

17 Mar 2022

OU student wins NIH Award for a technique that may help improve pancreatic cancer detection

A University of Oklahoma engineering student has received the rare honor of being awarded the Ruth L. Kirschstein Predoctoral Individual National Research Service Award from the National Cancer Institute at the National Institutes of Health.

17 Mar 2022

It was already hard to find Evusheld, a covid prevention therapy. Now it’s even harder.

As immunocompromised people across the country work to get Evusheld, a potentially lifesaving covid therapy, several hundred providers of the injections were removed from a federal dataset on Wednesday night, making the therapy even harder to locate.

17 Mar 2022

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Researchers demonstrated that the thiopurines block coronaviruses spike protein assembly and integration into progeny virions.

17 Mar 2022

Mayo Clinic researchers report differences in genomic data quality among racial groups

Mayo Clinic researchers studied the differences in genomic data quality among racial groups in one of the largest and most widely used cancer research datasets, The Cancer Genome Atlas.

17 Mar 2022

Impact of B-cell depletion therapy on hospitalized COVID-19 patients

Researchers assessed the clinical outcomes in patients hospitalized with SARS-CoV-2 infections who were previously treated with B-cell depletion therapy.

17 Mar 2022

Brain-wide association studies need thousands of people to achieve higher reproducibility

As brain scans have become more detailed and informative in recent decades, neuroimaging has seemed to promise a way for doctors and scientists to "see" what's going wrong inside the brains of people with mental illnesses or neurological conditions.

16 Mar 2022

Antimicrobial resistance in COVID-19

Researchers discuss the impact of this extensive use of antibiotics on the rise of antimicrobial resistance.

16 Mar 2022

Transcription factors work together to drive cancer cell proliferation

Scientists have discovered that a well-established cancer cell transcription factor and its newly identified co-factor work together to drive cancer cell proliferation, according to findings published in Science Advances.

16 Mar 2022

Novel oncogenic gene fusions identified in lung and pancreatic cancer

A Yale Cancer Center research team has identified novel oncogenic gene fusions in lung and pancreatic cancer, as well as sarcoma.

16 Mar 2022

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

High-grade serous carcinoma is the most aggressive form of ovarian cancer and accounts for the majority of advanced-stage cases.

16 Mar 2022

Elevated triglyceride levels may increase risk of second stroke, even while on statin therapy

Stroke can have many causes. An atherothrombotic stroke is caused by a clot that forms from plaques that build up within blood vessels in the brain.

16 Mar 2022

SLU physician-scientist receives NIH funding for Short Bowel Syndrome research

A Saint Louis University School of Medicine scientist and SLUCare physician has received funding from the National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health (NIH) to study Short Bowel Syndrome (SBS).

16 Mar 2022

Toxin-producing yeast strains may damage the gut of patients with inflammatory bowel disease

Individual Candida albicans yeast strains in the human gut are as different from each other as the humans that carry them, and some C. albicans strains may damage the gut of patients with inflammatory bowel disease (IBD), according to a new study from researchers at Weill Cornell Medicine.

16 Mar 2022

Sneaking large drug-carrying biological molecules into cells using a novel drug delivery system

Scientists from Nanyang Technological University, Singapore have developed a novel method of delivering drugs into human cells using large biological molecules, by first encasing them in a protein-based microdroplet.

16 Mar 2022

Study evaluates monoclonal antibody treatment for pregnant COVID-19 patients

Researchers evaluated COVID-19 monoclonal antibody treatment in pregnant and postpartum women.

16 Mar 2022

Prolonged unconsciousness is common in COVID-19 patients, recovery often takes days or even weeks

During the first wave of the COVID-19 pandemic, many patients in intensive care units did not recover consciousness after their breathing tubes were removed and their sedation was stopped, leaving clinicians and families with difficult decisions about whether to continue life-sustaining therapy.

16 Mar 2022

In silico identification of novel curcumin derivatives as potential inhibitors against SARS-CoV-2 enzymes

Researchers identified curcumin derivatives as potential inhibitors of SARS-CoV-2 enzymes.

16 Mar 2022

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Research carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) has demonstrated that mixing mitochondrial DNAs (mtDNAs) of different origins can have damaging effects over the medium and long term.

16 Mar 2022

Therapy News and Research

University of Kentucky begins world’s first clinical trial for LATE

People with elevated blood pressure upon standing more likely to have risk for cardiovascular events

OU student wins NIH Award for a technique that may help improve pancreatic cancer detection

It was already hard to find Evusheld, a covid prevention therapy. Now it’s even harder.

Study reports thiopurines inhibit the replication of the betacoronaviruses HCoV-OC43 and SARS-CoV-2

Mayo Clinic researchers report differences in genomic data quality among racial groups

Impact of B-cell depletion therapy on hospitalized COVID-19 patients

Brain-wide association studies need thousands of people to achieve higher reproducibility

Antimicrobial resistance in COVID-19

Transcription factors work together to drive cancer cell proliferation

Novel oncogenic gene fusions identified in lung and pancreatic cancer

Novel metabolic mechanisms contribute to how ovarian cancer evades immune attack, research finds

Elevated triglyceride levels may increase risk of second stroke, even while on statin therapy

SLU physician-scientist receives NIH funding for Short Bowel Syndrome research

Toxin-producing yeast strains may damage the gut of patients with inflammatory bowel disease

Sneaking large drug-carrying biological molecules into cells using a novel drug delivery system

Study evaluates monoclonal antibody treatment for pregnant COVID-19 patients

Prolonged unconsciousness is common in COVID-19 patients, recovery often takes days or even weeks

In silico identification of novel curcumin derivatives as potential inhibitors against SARS-CoV-2 enzymes

Study reveals how to identify and avoid risks related to mitochondrial therapeutic interventions

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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