immunity News and Research

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Innovative study brings us closer to an explanation for Crohn's disease

Twenty-five per cent of Crohn's disease patients have a mutation in what is called the NOD2 gene, but it is not precisely known how this mutation influences the disease.

9 Jul 2009

Developed countries must address global warming to prevent disease, hunger in developing world

Pollution from the world's wealthiest countries is spreading disease and hunger in developing countries, according to a new Oxfam International report, which calls on developed countries to address global warming when G8 leaders meet in Italy, the Globe and Mail reports.

7 Jul 2009

Brain's immune system may cause chronic seizures

Chronic seizures caused by traumatic head injuries may result from chemicals released by the brain's immune system attempting to repair the injured site, according to a study led by the University of Colorado at Boulder.

6 Jul 2009

Research examines history of H1N1 and provides cautionary tale about the use of extinct viruses

The current H1N1 swine flu strain has genetic roots in an illness that sickened pigs at the 1918 Cedar Rapids Swine Show in Iowa, report infectious disease experts at the University of Pittsburgh Graduate School of Public Health in the New England Journal of Medicine.

30 Jun 2009

Insect venom shots work for severe "local" sting reactions, too

The same bee and other insect venom shots that doctors use to prevent deadly systemic reactions to insect stings can also tone down large local allergic reactions that, while not dangerous, can be painful and inconvenient, a Johns Hopkins study shows. Results of the study are published in the June 2009 Journal of Allergy and Clinical Immunology.

29 Jun 2009

Forget swine flu - whooping cough far more of a worry!

Queensland Health authorities say there has been a surge in the number of whooping cough cases in far north Queensland - according to health officials there have been 205 cases of the disease in the state's far north already this year, seven times higher than the same time last year and Dr. Steven Donohue at the Tropical Population Health Service is warning parents to have their children immunised.

24 Jun 2009

Microbial and maternal influences on allergic sensitization during childhood

When infected, the body has two types of immune defence to deploy - innate immunity and acquired immunity. In her dissertation, Shanie Saghafian Hedengren studies monocytes, a type of white blood corpuscles that are part of the innate immune system.

23 Jun 2009

Do viruses make bacteria more deadly?

In England and Wales, the national health statistics in 2007 showed that there were 8,324 death certificates which named Clostridium difficile. This is a bacterium which causes severe diarrhoea in humans and animals as the underlying cause of death, a 28% increase from 2006.

22 Jun 2009

Antibiotics diminish diversity of helpful gutmicrobes

It's common knowledge that a protective navy of bacteria normally floats in our intestinal tracts. Antibiotics at least temporarily disturb the normal balance. But it's unclear which antibiotics are the most disruptive, and if the full array of "good bacteria" return promptly or remain altered for some time.

18 Jun 2009

Targeting children may be an effective use of limited supplies of flu vaccine

Targeting children may be an effective use of limited supplies of flu vaccine, according to research funded by the Wellcome Trust and the EU. The study suggests that, used to support other control measures, this could help control the spread of pandemics such as the current swine flu.

17 Jun 2009

“Life force” linked to body’s ability to withstand stress

Our ability to withstand stress-related, inflammatory diseases may be associated, not just with our race and sex, but with our personality as well, according to a study published in the July issue of the journal Brain, Behavior and Immunity. Especially in aging women, low levels of the personality trait extraversion may indicate that blood levels of a key inflammatory molecule have crossed over a threshold linked to a doubling of risk of death within five years.

17 Jun 2009

Household structure and infectious disease transmission

Targeting children may be an effective use of limited supplies of flu vaccine, according to research at the University of Warwick funded by the Wellcome Trust and the EU. The study suggests that, used to support other control measures, this could help control the spread of pandemics such as the current swine flu.

17 Jun 2009

Preventing spread of infectious diseases is everyone’s responsibility – and everyone’s job

According to a report published today, we must all share responsibility for preventing the spread of diseases such as swine flu, SARS, avian influenza, diarrhoeal and skin diseases, and even the common cold.

16 Jun 2009

90 per cent of the world's population won't have access to antivirals in pandemic - generic drugs may help though

Almost 90 per cent of the world's population will not have timely access to affordable supplies of vaccines and antiviral agents in the current influenza pandemic, but it is possible that inexpensive generic drugs that are readily available, even in developing countries, could save millions of lives.

13 Jun 2009

Mouse experiments shed light on age effects in arthritis

Older mice are more susceptible to proteoglycan-induced arthritis (PGIA). Researchers writing in BioMed Central's open access journal Immunity & Ageing have shown, for the first time, that young mice are completely resistant, but become fully susceptible to the disease with age.

10 Jun 2009

AP/Washington Post examines experimental malaria vaccine, mutant mosquitoes to combat malaria

During the 1990s, Sanaria CEO Stephen Hoffman "irradiated malaria-carrying mosquitoes to weaken the parasites inside them, and he and 13 colleagues subjected themselves to more than 1,000 bites," according to the AP/Washington Post.

9 Jun 2009

Cancer vaccine efficacy enhanced using anti-diabetic drug Metformin

After a vaccination or an infection, the human immune system remembers to keep protecting against invaders it has already encountered, with the aid of specialized B-cells and T-cells. Immunological memory has long been the subject of intense study, but the underlying cellular mechanisms regulating the generation and persistence of long-lived memory T cells remain largely undefined. Now, University of Pennsylvania School of Medicine researchers have found that a common anti-diabetic drug might enhance the effectiveness of vaccines. The findings are described this week in an advanced online publication of Nature.

4 Jun 2009

Indonesia to host AIDS congress; smoking ban in Ghana

Indonesia will host the 9th International Congress on AIDS in Asia and the Pacific region, August 3 – 13 in Bali, organizers of the event announced Wednesday, Xinhua reports.

3 Jun 2009

Metformin may 'revolutionize' cancer-fighting treatments

Researchers at McGill University and the University of Pennsylvania have discovered that a widely used anti-diabetic drug can boost the immune system and increase the potency of vaccines and cancer treatments. Their findings will be published June 3 in the journal Nature.

3 Jun 2009

Discovery of new arenavirus associated with hemorrhagic fever – first identified in nearly four decades

Scientists at Columbia University's Mailman School of Public Health, the South African National Institute for Communicable Diseases of National Health Laboratory Service (NICD-NHLS), the U.S. Centers for Disease Control and Prevention, and Roche's 454 Life Sciences Corporation have discovered the new virus responsible for a highly fatal hemorrhagic fever outbreak in Zambia and South Africa in late 2008.

2 Jun 2009