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Simplifying the analysis of social contacts using novel computational method

How society organizes affects different phenomena, from the transmission of information to the spread of contagious diseases. The more links we establish with each other via social and transportation networks, the more spread is favored. To study the dynamics of complex systems, such as society, we can infer these networks – in which nodes, representing individuals, connect through lines – from real-world data. However, these networks are usually large, dense, and cumbersome to manipulate.

25 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Women with a BRCA1 or BRCA2 pathogenic variant have high risk of cancer after age 50

Although genetic mutations in BRCA1 or BRCA2 are associated with a younger onset of breast and ovarian cancer, women with these genetic mutations continue to face a high risk of cancer incidence after age 50, even if they have not been previously diagnosed with cancer.

24 Feb 2023

Demographic factors linked to low telemedicine literacy

Demographic factors including low income and living in a rural area are linked to low telemedicine literacy – which may limit access to plastic surgeons and other healthcare providers at a time of expanding use of telehealth and video visits, according to a report in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

24 Feb 2023

Cedars-Sinai investigator receives award for research identifying racial disparities in treatment for uterine fibroids

Rebecca Schneyer, MD, has received the Medstar National Center for Advanced Pelvic Surgery Diversity and Inclusion Award given by the Foundation of the AAGL.

24 Feb 2023

Technology-assisted pregnancies increase the likelihood of preeclampsia

People who became pregnant using assisted reproductive technologies were found to be over twice as likely to develop preeclampsia than those with traditional pregnancies, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

24 Feb 2023

Health status, rather than age linked to rising rates of adverse pregnancy outcomes

Rising rates of adverse pregnancy outcomes, such as hypertensive disorders of pregnancy, preterm birth and low birthweight, over the past 10 years are largely attributable to the health status of a person before they get pregnant, rather than age, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

24 Feb 2023

Cleft lip and palate surgeries are economically undervalued relative to pediatric craniofacial procedures

Plastic surgery procedures performed to correct cleft lip and palate deformities in infants and children are economically undervalued, relative to pediatric craniofacial procedures, concludes an analysis in the March issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

24 Feb 2023

Discovery of a T cell subset points to new treatment for COPD exacerbations

Respiratory viral infections pose significant morbidity and mortality to patients with chronic lung diseases like emphysema and COPD, causing exacerbations that drive destruction of normal lung tissue, and leading to one of the most common diagnoses for hospital admissions.

24 Feb 2023

Study highlights COVID-19 vaccine safety among children

Researchers evaluate COVID-19 vaccine-associated serious adverse events following immunization among five- to 17-year-old children.

23 Feb 2023

Reducing social media use improves appearance and weight esteem in distressed teens

Teens and young adults who reduced their social media use by 50% for just a few weeks saw significant improvement in how they felt about both their weight and their overall appearance compared with peers who maintained consistent levels of social media use, according to research published by the American Psychological Association.

23 Feb 2023

UMSOM researchers unravel the molecular components involved in abdominal aneurysms

When the artery that supplies the stomach and the liver forms a bulge that ruptures, this medical emergency results in the deaths of 50 percent of patients before they reach the hospital.

23 Feb 2023

Cleaner air improves lung capacity of children and adolescents

As air pollution in Stockholm has decreased, so has the lung capacity of children and adolescents has improved, a new study published in the European Respiratory Journal reports.

23 Feb 2023

Skipping meals can trigger a negative effect on immune cells

Fasting may be detrimental to fighting off infection, and could lead to an increased risk of heart disease, according to a new study by the Icahn School of Medicine at Mount Sinai.

23 Feb 2023

Study focuses on the impact of obstetric injuries on women’s lives two decades later

Bowel leakage, the need for anal incontinence protection and a restricted social life may cause severe, decades-long suffering among women with obstetric injuries to the anal opening, according to a study from the University of Gothenburg.

23 Feb 2023

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Oleic acid, the principal component of olive oil, has properties that help to prevent cancer and Alzheimer's disease and to lower cholesterol.

23 Feb 2023

Preventative antibiotic given during labor can reduce the risk of sepsis and death

A single oral dose of the antibiotic azithromycin given during labor can dramatically reduce the risk of sepsis and death among women following childbirth, according to a large multi-country clinical trial, as a UN report warns of "stagnation" in maternal health.

23 Feb 2023

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Targeted drugs have been developed to supplement chemotherapy in the treatment of cancer. These drugs only affect cancer cells, leaving healthy cells alone.

23 Feb 2023

Disabilities in people with heart disease underreported in clinical trials

Disabilities were underreported in clinical trial data and commonly used as a basis for exclusion from trial participation in an analysis of 80 recent trials involving cardiovascular outcomes, according to a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

23 Feb 2023

Hormone replacement therapy for gender dysphoria may increase risk of serious cardiac events

People with gender dysphoria taking hormone replacements as part of gender affirmation therapy face a substantially increased risk of serious cardiac events, including stroke, heart attack and pulmonary embolism, according to a study presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

23 Feb 2023

Hospital News and Research

Simplifying the analysis of social contacts using novel computational method

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Women with a BRCA1 or BRCA2 pathogenic variant have high risk of cancer after age 50

Demographic factors linked to low telemedicine literacy

Cedars-Sinai investigator receives award for research identifying racial disparities in treatment for uterine fibroids

Technology-assisted pregnancies increase the likelihood of preeclampsia

Health status, rather than age linked to rising rates of adverse pregnancy outcomes

Cleft lip and palate surgeries are economically undervalued relative to pediatric craniofacial procedures

Discovery of a T cell subset points to new treatment for COPD exacerbations

Study highlights COVID-19 vaccine safety among children

Reducing social media use improves appearance and weight esteem in distressed teens

UMSOM researchers unravel the molecular components involved in abdominal aneurysms

Cleaner air improves lung capacity of children and adolescents

Skipping meals can trigger a negative effect on immune cells

Study focuses on the impact of obstetric injuries on women’s lives two decades later

Oleic acid: Principal component of olive oil responsible for many health-promoting properties

Preventative antibiotic given during labor can reduce the risk of sepsis and death

Study identifies a potential new targeted drug for treating acute myeloid leukemia

Disabilities in people with heart disease underreported in clinical trials

Hormone replacement therapy for gender dysphoria may increase risk of serious cardiac events

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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