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New insights into POT-1/TTP-1 protein complex

New insights into a protein complex that regulates the very tips of chromosomes could improve methods of screening anti-cancer drugs.

30 Nov 2012

Research examines tumor-initiating events that lead to pancreatic cancer

A diagnosis of pancreatic cancer is particularly devastating since the prognosis for recovery is usually poor, with the cancer most often not detected until late stages.

30 Nov 2012

Exposure to essential oil for 1 hour would be effective in reducing heart rate and blood pressure

The scents which permeate our health spas from aromatic essential oils may provide more benefits than just a sense of rest and well-being.

30 Nov 2012

Combination of chemotherapy and selumetinib shows promise against NSCLC

A new study by an international team of investigators led by Dana-Farber Cancer Institute scientists is the first to demonstrate that chemotherapy and a new, targeted therapy work better in combination than chemotherapy alone in treating patients with the most common genetic subtype of lung cancer.

30 Nov 2012

Study shows how anaplasma phagocytophilum subverts natural processes

Bacteria that cause the tick-borne disease anaplasmosis in humans create their own food supply by hijacking a process in host cells that normally should help kill the pathogenic bugs, scientists have found.

30 Nov 2012

Seven U of M faculty named American Association for the Advancement of Science Fellows

Seven faculty at the University of Minnesota have been named a Fellow of the American Association for the Advancement of Science (AAAS). Election as an AAAS Fellow is an honor bestowed upon AAAS members by their peers, and recognizes scientifically or socially distinguished efforts to advance science or its applications.

30 Nov 2012

Wichita State professor hopes to understand how cancer cells spread and become fatal

Through her research at Wichita State University, assistant chemistry professor Moriah Beck hopes to understand how cancer cells spread and become fatal.

30 Nov 2012

Neuro-inflammation plays a crucial role in initiating prion disease

In a recent publication, researchers of the Computational Biology group at the Luxembourg Centre for Systems Biomedicine showed that neuro-inflammation plays a crucial role in initiating prion disease.

30 Nov 2012

Cleveland Clinic researcher names American Association for the Advancement of Science Fellow

Cleveland Clinic researcher Jun Qin, Ph.D., has been named a Fellow of the American Association for the Advancement of Science (AAAS). As part of the Molecular Cardiology Department in the Lerner Research Institute, Qin was elected as an AAAS Fellow for exemplary contributions to the field of cell signaling.

30 Nov 2012

German Research Foundation to establish new CRC at Mainz University Medical Center

On January 1, 2013, the German Research Foundation (DFG) will establish a new Collaborative Research Center (CRC) at the University Medical Center of Johannes Gutenberg University Mainz (JGU).

30 Nov 2012

African Americans experience faster progression of CKD during later stages

Among individuals with chronic kidney disease (CKD), African Americans experience faster progression of the disease during later stages compared with other races, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

30 Nov 2012

Novel SIRT2 inhibitor protects against neuronal damage in animal models of Huntington's

Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and extended survival in two animal models of Huntington's disease.

30 Nov 2012

Scientists define key underlying process implicated in multiple sclerosis

Scientists at the Gladstone Institutes have defined for the first time a key underlying process implicated in multiple sclerosis (MS)-a disease that causes progressive and irreversible damage to nerve cells in the brain and spinal cord. This discovery offers new hope for the millions who suffer from this debilitating disease for which there is no cure.

30 Nov 2012

Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting

Epizyme, Inc., a biopharmaceutical company leading the creation of personalized therapeutics to treat patients with genetically defined cancers, today announced the presentation of data evaluating the preclinical safety and efficacy of two of the Company's novel, potent and selective small molecule inhibitors. These inhibitors individually target DOT1L and EZH2, members of a class of epigenic enzymes called histone methyltransferases (HMTs).

30 Nov 2012

Alberta Children's Hospital performs first liver cell transplant in Calgary, Canada

A three-month-old Winnipeg girl has become the first patient in Canada to receive an experimental and potentially life-saving form of therapy to improve the function of her liver.

29 Nov 2012

ArmaGen closes $17M Series A financing

ArmaGen Technologies, Inc. today announced the closing of a $17 million Series A financing to support the development of brain-penetrating recombinant protein therapeutics.

29 Nov 2012

Methodist dietitian offers tips to prevent holiday weight gain

The holiday season is officially in full gear and with it comes the tempting Thanksgiving-to-New-Year's food fest. While research shows that the average person really only gains about a pound over the course of the holidays, it can still have a big cumulative effect on waistlines. That's because the extra weight usually doesn't come off the following year.

29 Nov 2012

Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia

A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of The New England Journal of Medicine.

29 Nov 2012

Study shows how PTPN22 variant linked with T1D influences susceptibility to autoimmunity

As part of their ongoing research on the role of genes in the development of type 1 diabetes, Joslin Diabetes Center scientists, in collaboration with scientists at the University of Würzburg, have demonstrated how a genetic variant associated with type 1 diabetes and other autoimmune diseases influences susceptibility to autoimmunity. The findings appear in the upcoming issue of Diabetes.

29 Nov 2012

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.

29 Nov 2012

G Protein News and Research

New insights into POT-1/TTP-1 protein complex

Research examines tumor-initiating events that lead to pancreatic cancer

Exposure to essential oil for 1 hour would be effective in reducing heart rate and blood pressure

Combination of chemotherapy and selumetinib shows promise against NSCLC

Study shows how anaplasma phagocytophilum subverts natural processes

Seven U of M faculty named American Association for the Advancement of Science Fellows

Wichita State professor hopes to understand how cancer cells spread and become fatal

Neuro-inflammation plays a crucial role in initiating prion disease

Cleveland Clinic researcher names American Association for the Advancement of Science Fellow

German Research Foundation to establish new CRC at Mainz University Medical Center

African Americans experience faster progression of CKD during later stages

Novel SIRT2 inhibitor protects against neuronal damage in animal models of Huntington's

Scientists define key underlying process implicated in multiple sclerosis

Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting

Alberta Children's Hospital performs first liver cell transplant in Calgary, Canada

ArmaGen closes $17M Series A financing

Methodist dietitian offers tips to prevent holiday weight gain

Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia

Study shows how PTPN22 variant linked with T1D influences susceptibility to autoimmunity

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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