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Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio 1 Dec 2021

Nanoengineers develop a new approach to effectively deliver mRNA into cells

Nanoengineers at the University of California San Diego have developed a new and potentially more effective way to deliver messenger RNA (mRNA) into cells.

30 Nov 2021

New method can precisely, rapidly correct genetic alterations in patient cells

Researchers in the University of Helsinki and University Hospital Helsinki have developed a method to precisely and rapidly correct genetic alterations in the cultured patient cells.

30 Nov 2021

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Immunotherapies have shown striking clinical benefit in the treatment of many cancers, especially when used in combination with chemotherapy.

30 Nov 2021

Researchers genetically map cell types that make up the mouse iris

Johns Hopkins Medicine researchers report they have genetically mapped the cell types that make up the mouse iris — the thin disc of pigmented tissue that, in humans, gives eyes their distinct colors.

30 Nov 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

As the COVID-19 pandemic nears the two-year mark, Northwestern Medicine scientists continue to tackle every facet of the disease, from investigating coronavirus vaccines' potential for providing immunity against similar coronaviruses to developing novel rapid antigen-based tests and examining disparities in COVID-19 case and mortality rates in Chicago.

30 Nov 2021

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

In the largest genetic study of suicide attempts to date, researchers have identified a region of the genome on chromosome 7 containing DNA variations that increase the risk that a person will attempt suicide.

30 Nov 2021

New method helps correct genetic alterations in the cultured patient cells rapidly

Researchers in the University of Helsinki and University Hospital Helsinki have developed a method to precisely and rapidly correct genetic alterations in the cultured patient cells.

30 Nov 2021

Industrially processed foods increase the risk of a second heart attack or a fatal stroke

Ultra-processed foods are a major public health concern for their potential adverse effects on health. Now a study by the Department of Epidemiology and Prevention of the I.R.C.C.S. Neuromed in Pozzilli (Italy) explores the health effects of a large dietary share of ultra-processed food on people already suffering from cardiovascular diseases.

30 Nov 2021

New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

A group led by Prof. Han Dong of Peking University School of Stomatology reported for the first time hand preaxial polydactyly in patients with tooth agenesis carrying a previously unknown mutation of low-density lipoprotein receptor-related protein 6 (LRP6).

29 Nov 2021

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Scientists at the University of North Carolina at Chapel Hill School of Medicine and colleagues have demonstrated that rare variants in the ANK2 gene, consistently found in individuals with autism spectrum disorder (ASD), can alter architecture and organization of neurons, potentially contributing to autism and neurodevelopmental comorbidities.

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

Low neutralizing antibody titers against SARS-CoV-2 Mu in BNT162b2 vaccinated

Researchers assess the neutralizing antibody titers in BNT162b2-vaccinated people against SARS-CoV-2 isolates from the Mu, Gamma, and B.1.111 lineages.

28 Nov 2021

Complex RNA structures could have untapped therapeutic potential in the fight against COVID-19

To the untrained eye, the loops, kinks and folds in the single strand of RNA that makes up the coronavirus genome look like a jumble of spaghetti or tangled yarn. But to researchers like Amanda Hargrove, a chemistry professor at Duke University, the complex shapes that RNA takes on as it folds upon itself could have untapped therapeutic potential in the fight against COVID-19.

26 Nov 2021

Genetic ancestry can explain population-level differences in immune response to the flu virus

A new study aimed at explaining differential susceptibility to viral epidemics reveals that ancestry and associated genetic variation can explain population-level differences in the immune response to the flu virus and perhaps also to COVID-19.

26 Nov 2021

Viral RNA in the blood found to be a reliable indicator of COVID-19 mortality risk

The amount of a SARS-CoV-2 genetic material - viral RNA - in the blood is a reliable indicator in detecting which patients will die of the disease, a team led by Université de Montréal medical professor Dr. Daniel Kaufmann has found.

26 Nov 2021

Comprehensive genomic study maps the global resurgence of syphilis

The most comprehensive genomic study of syphilis to date has mapped the recent resurgence of the disease around the world.

26 Nov 2021

WHO designates Omicron (B.1.1.529) as SARS-CoV-2 Variant of Concern

The Technical Advisory Group on SARS-CoV-2 Virus Evolution (TAG-VE) is an independent group of experts that periodically monitors and evaluates the evolution of SARS-CoV-2 and assesses if specific mutations and combinations of mutations alter the behavior of the virus.

26 Nov 2021

Prediction of severe infection based on SARS-CoV-2 genomic analysis

A group of researchers have used these SARS-CoV-2 sequence data and developed an algorithm to predict severity based upon viral mutations.

26 Nov 2021

Genetic News and Research

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

Nanoengineers develop a new approach to effectively deliver mRNA into cells

New method can precisely, rapidly correct genetic alterations in patient cells

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Researchers genetically map cell types that make up the mouse iris

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

Northwestern researchers continue to tackle every facet of COVID-19 pandemic

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

New method helps correct genetic alterations in the cultured patient cells rapidly

Industrially processed foods increase the risk of a second heart attack or a fatal stroke

New phenotype of LRP6 mutation reported for the first time in patients with tooth agenesis

Rare variants in high-risk autism gene can alter architecture and organization of neurons, study finds

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Low neutralizing antibody titers against SARS-CoV-2 Mu in BNT162b2 vaccinated

Complex RNA structures could have untapped therapeutic potential in the fight against COVID-19

Genetic ancestry can explain population-level differences in immune response to the flu virus

Viral RNA in the blood found to be a reliable indicator of COVID-19 mortality risk

Comprehensive genomic study maps the global resurgence of syphilis

WHO designates Omicron (B.1.1.529) as SARS-CoV-2 Variant of Concern

Prediction of severe infection based on SARS-CoV-2 genomic analysis

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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