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Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

The human body is home to a complex ecosystem of microbes increasingly recognized as having a critical role in both health and disease.

14 Dec 2010

GTx announces Capesaris proof of concept clinical trail in men with advanced prostate cancer

BETHESDA, Md.,GTx, Inc. this weekend presented results of the Capesaris™ (GTx-758) proof of concept pharmacokinetic-pharmacodynamic (PK/PD) clinical trial at the Annual Meeting of the Society of Urologic Oncology.

14 Dec 2010

Even small amount of alcohol increases chances of developing cancer

When raising your glass at this year's holiday toast, choose your beverage wisely, say experts at The University of Texas MD Anderson Cancer Center. If adults wish to drink alcohol, they should select drinks low in calories and alcohol content to limit cancer risk.

14 Dec 2010

Chimerix reports positive results from CMX157 Phase 1 clinical trial for HIV

Chimerix, Inc., a pharmaceutical company developing orally-available antiviral therapeutics, today announced first-in-human Phase 1 clinical trial results for CMX157 demonstrating a favorable safety, tolerability and drug distribution profile.

14 Dec 2010

Clinical trail shows 2009 H1N1 influenza vaccine safe and effective in asthma patients

Results from a government-sponsored clinical trial of inactivated 2009 H1N1 influenza vaccine in people with asthma indicate that a single dose of vaccine was safe and induced a strong immune response predictive of protection.

14 Dec 2010

Osteoporosis drug reduces bone loss in oral cancer

A drug currently approved for osteoporosis treatment has been shown to reduce bone loss in a study of mice with oral cancer, suggesting it could serve as an important supplemental therapy in patients with head and neck cancers that erode bone.

14 Dec 2010

Senator Leahy calls for U.S. to suspend direct aid to Haiti's government, visas for Haitian officials

Senator Patrick Leahy (D-Vt.), who chairs the Senate Appropriations Committee's Subcommittee on the State, Foreign Operations, and Related Programs, "on Friday urged President Barack Obama's administration to suspend direct aid to Haiti's government and visas for its top officials until it ensures a fair and democratic outcome to disputed national elections," Reuters reports.

14 Dec 2010

Top-line results from Inhibitex's FV-100 Phase II clinical trial for treatment of shingles

Inhibitex, Inc. today reported top-line safety and efficacy data from its Phase II clinical trial of FV-100, an oral antiviral compound being developed to treat herpes zoster, more commonly referred to as shingles. The study was the first clinical trial to assess the antiviral activity of FV-100, included 350 shingles patients and compared two once-daily doses of FV-100 (200 mg and 400 mg) to an active control, valacyclovir, one of the most commonly-used antiviral drugs to treat shingles.

14 Dec 2010

New osteoporosis drug appears to reduce bone loss in mice with oral cancer

14 Dec 2010

Federal judge poised to issue ruling in Virginia health law challenge

A Virginia federal court judge is expected today to issue a much-awaited ruling on whether the new health law violates the Constitution. Meanwhile, legal arguments are scheduled to take place Thursday in a Florida courtroom regarding a separate challenge to the health overhaul.

13 Dec 2010

New positive data on Generex Oral-lyn published in Diabetes, Obesity and Metabolism

Generex Biotechnology Corporation announced today that the peer-reviewed scientific journal Diabetes, Obesity and Metabolism has published new positive data in respect of Generex Oral-lyn™, the Company's proprietary buccal insulin spray product.

13 Dec 2010

Zogenix's SUMAVEL DosePro Needle-free Delivery System wins 2010 Most Innovative Product award

Zogenix, Inc. today announced that CONNECT, a regional San Diego nonprofit organization, selected SUMAVEL® DosePro™ (sumatriptan injection) Needle-free Delivery System as a 2010 Most Innovative Product (MIP) winner at the MIP Awards Luncheon on December 10, 2010.

13 Dec 2010

First Edition: December 13, 2010

Today's health policy headlines highlight today's expected ruling by a Virginia federal court judge on the health law's constitutionality.

13 Dec 2010

OraSure commences enrollment in final study for FDA approval of OraQuick Rapid HIV-1/2 OTC test

OraSure Technologies, Inc., the market leader in oral fluid diagnostics, announced today that it has enrolled the first subject in its final phase of clinical studies for United States Food and Drug Administration ("FDA") approval of the Company's OraQuick® Rapid HIV-1/2 test for sale in the U.S. consumer or over-the-counter ("OTC") market.

13 Dec 2010

Syndax reports promising results from entinostat preclinical studies in breast cancer

Syndax Pharmaceuticals, Inc., a clinical-stage epigenetics oncology company, announces results from two preclinical studies on entinostat, an orally bioavailable, highly selective, class I histone deacetylase (HDAC) inhibitor, in animal models of breast cancer. The data are being presented as oral poster discussions at the San Antonio Breast Cancer Symposium December 8 through December 12 in San Antonio Texas.

13 Dec 2010

FDA issues final guidance for public's comments at advisory committee meetings

The U.S. Food and Drug Administration today issued final guidance for people who wish to comment during the agency's advisory committee meetings. The guidance provides instructions on how to request a time to speak and how FDA staff should respond to requests to speak at the meetings.

13 Dec 2010

Better approaches to ovarian cancer screening could lower cancer deaths

Cancer prevention experts have long been frustrated by the lack of a meaningful way to screen women for ovarian cancer. It is a relatively rare disease that often progresses with few symptoms until it is too late for potentially curative treatments, and elevated values of the most commonly used biomarker used in screening, CA125, are also related to other disorders.

13 Dec 2010

New challenges to FDA's 'no risk' classification of mercury fillings

FDA Device Division, still concerned about mercury toxicity in American dentistry, is convening yet another professional panel review regarding safety issues. A nationwide convergence of scientists, dental and medical professionals, lead by the International Academy of Oral Medicine and Toxicology (IAOMT) are provoking new challenges to the Food and Drug Administration's (FDA) July'09 "no risk" classification of mercury fillings .

10 Dec 2010

Research roundup: For-profit hospitals' readmission rate, containing self-referrals, children's dental health, revisiting McAllen

For-Profit Hospital Status And Rehospitalizations At Different Hospitals: An Analysis of Medicare Data - "Rehospitalization within the first 30 days of discharge affects 1 in 5 hospitalized Medicare fee-for-service patients and costs approximately $17.4 billion in payments annually ... the top 4 factors most related to the risk for rehospitalization at a different facility were initial admission to a for-profit index hospital … lower-volume index hospital (hospitals with <1000 annual discharges) … hospital with a major medical school affiliation … and being disabled."

10 Dec 2010

Positive preliminary results from tivozanib-paclitaxel combination Phase 1b trial in metastatic breast cancer

AVEO Pharmaceuticals, Inc., a biopharmaceutical company focused on discovering, developing and commercializing cancer therapeutics, today announced preliminary results from an ongoing Phase 1b clinical trial evaluating the company's lead product candidate, tivozanib, a highly potent and selective inhibitor of VEGF receptors 1, 2, and 3, in combination with paclitaxel (Taxol®), a standard chemotherapy regimen, in patients with metastatic breast cancer.

10 Dec 2010

Oral News and Research

Scientists perform metagenomic analysis of bacterial immune system for personalized oral health care

GTx announces Capesaris proof of concept clinical trail in men with advanced prostate cancer

Even small amount of alcohol increases chances of developing cancer

Chimerix reports positive results from CMX157 Phase 1 clinical trial for HIV

Clinical trail shows 2009 H1N1 influenza vaccine safe and effective in asthma patients

Osteoporosis drug reduces bone loss in oral cancer

Senator Leahy calls for U.S. to suspend direct aid to Haiti's government, visas for Haitian officials

Top-line results from Inhibitex's FV-100 Phase II clinical trial for treatment of shingles

New osteoporosis drug appears to reduce bone loss in mice with oral cancer

Federal judge poised to issue ruling in Virginia health law challenge

New positive data on Generex Oral-lyn published in Diabetes, Obesity and Metabolism

Zogenix's SUMAVEL DosePro Needle-free Delivery System wins 2010 Most Innovative Product award

First Edition: December 13, 2010

OraSure commences enrollment in final study for FDA approval of OraQuick Rapid HIV-1/2 OTC test

Syndax reports promising results from entinostat preclinical studies in breast cancer

FDA issues final guidance for public's comments at advisory committee meetings

Better approaches to ovarian cancer screening could lower cancer deaths

New challenges to FDA's 'no risk' classification of mercury fillings

Research roundup: For-profit hospitals' readmission rate, containing self-referrals, children's dental health, revisiting McAllen

Positive preliminary results from tivozanib-paclitaxel combination Phase 1b trial in metastatic breast cancer

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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