Immunization News and Research

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Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Researchers demonstrate that SARS-CoV-2 RBD-based nanoparticle vaccine induces neutralizing antibodies against SARS-CoV-2 variants.

2 Feb 2022

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Exposure to SARS-CoV-2 by infection or vaccination generates immune cells that provide long-term immunity. These long-lived memory T cells play a key role in preventing severe cases of Covid-19. Researchers at the University of Zurich have now discovered how these memory T cells form.

2 Feb 2022

Safety and immunogenicity of high-dose quadrivalent influenza vaccine and mRNA-1273 vaccine booster in older adults

A new study has determined the safety and immunogenicity after concomitant administration of QIV-HD and a third dose of the mRNA-1273 vaccine among older adults in the USA

2 Feb 2022

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

The first generation of COVID-19 vaccines have been highly effective, but also have limitations: their efficacy can wane without a booster shot, and they may be less effective against some variants.

2 Feb 2022

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

A team of scientists from the United States has recently demonstrated that current coronavirus disease 2019 (COVID-19) vaccines induce robust spike-specific T cell responses against the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

1 Feb 2022

Study reveals seven major determinants of mortality risk for patients with COVD-19 and thoracic cancer

The risk of death for patients with SARS-CoV-2 infection and thoracic cancer is based on seven major determinants, according to research published in the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer.

1 Feb 2022

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

In a new study, researchers evaluated the neutralizing antibody titers in mice vaccinated with messenger ribonucleic acid (mRNA) encoding SARS-CoV-2 spike (S) protein.

1 Feb 2022

Study shows mRNA booster dose eliminates immune escape observed with SARS-CoV-2 Omicron

Researchers examined total and neutralizing antibodies to the spike protein of SARS-CoV-2, and neutralizing antibodies against Washington-1 (WA-1) and variants of concern (VOC) including Beta, Delta, and Omicron in a longitudinal cohort.

31 Jan 2022

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

A new study posted to the medRxiv* preprint server has evaluated the effect of mRNA-based COVID-19 vaccination and boosting strategy on serum antibody responses in PAD patients against the original SARS-CoV-2 strain and circulating variants.

31 Jan 2022

Response to COVID-19 vaccine booster in seronegative kidney transplant recipients

Modification of vaccination strategies is needed to improve the immune response to SARS-CoV-2 vaccination in kidney transplant recipients (KTRs).

31 Jan 2022

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

In a new study, a team of researchers developed YF-S0, an exceptionally potent COVID-19 vaccine candidate using live-attenuated yellow fever vaccine YF17D as a vector.

31 Jan 2022

Prion-like domains in SARS-CoV-2 RBD and ACE2 play important functional roles in viral adhesion and entry

Scientists have recently detected and analyzed viral PrDs in the S protein of SARS-CoV-2, which are the novel regulators of virion assembly.

31 Jan 2022

Study explores factors associated with COVID-19 vaccine hesitancy in individuals with psoriasis

About 40% of people living with psoriasis have had delays to psoriasis treatment and care from the COVID-19 pandemic, according to a new study posted to the medRxiv* server. People of younger age and belonging to an ethnic minority group were more likely to be affected by these disruptions to care.

30 Jan 2022

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

Researchers screen kidney transplant recipients to evaluate their serological responses following immunization with three doses of the COVID-19 vaccine.

30 Jan 2022

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Researchers study the interaction between immunity to endemic coronaviruses and SARS-CoV-2.

30 Jan 2022

Intranasal vaccine with nanoparticles offers strong protection against influenza viruses

An influenza vaccine administered through the nose and constructed with nanoparticles that enhance immune response offers strong protection against different influenza virus strains, according to researchers in the Institute for Biomedical Sciences at Georgia State University.

29 Jan 2022

Immunization News and Research

Nanoparticle vaccine effective against eight SARS-CoV-2 variants in non-human primates

Study discovers how long-term memory T cells are formed after SARS-CoV-2 exposure

Safety and immunogenicity of high-dose quadrivalent influenza vaccine and mRNA-1273 vaccine booster in older adults

New nanoparticle SARS-CoV-2 vaccine shows stronger, broader, and more durable protection

COVID-19 vaccines induce robust cellular immune response against SARS-CoV-2 Omicron

Study reveals seven major determinants of mortality risk for patients with COVD-19 and thoracic cancer

Exploring beta-coronavirus neutralization by vaccine-induced murine antibody WS6

Study shows mRNA booster dose eliminates immune escape observed with SARS-CoV-2 Omicron

Study highlights importance of immunizing and boosting PAD syndromes patients with SARS-CoV-2 mRNA vaccines

Response to COVID-19 vaccine booster in seronegative kidney transplant recipients

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

Prion-like domains in SARS-CoV-2 RBD and ACE2 play important functional roles in viral adhesion and entry

Study explores factors associated with COVID-19 vaccine hesitancy in individuals with psoriasis

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Intranasal vaccine with nanoparticles offers strong protection against influenza viruses

Novel “prime and spike” vaccine strategy leverages existing immunity generated by primary COVID-19 vaccination

A synthesis of evidence sheds light on major immune components and mechanisms involved in COVID-19

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

Study demonstrates minimally invasive, aerosolized vaccine candidate to combat SARS-CoV-2

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