Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

FDA approves new vial size for CSL Behring’s Privigen to treat primary immunodeficiency

CSL Behring today announced that the United States Food and Drug Administration has approved a 40 g (400 mL) vial size for Privigen, immune globulin intravenous [human].

21 Feb 2013

UCB seeks FDA and EMA marketing authorization for Cimzia to treat active psoriatic arthritis

UCB announced today two new regulatory filings with the US Food and Drug Administration (FDA) and with the European Medicines Agency (EMA) to extend the marketing authorization for Cimzia (certolizumab pegol) for the treatment of adult patients with active psoriatic arthritis (PsA) and for adult patients with active axial spondyloarthritis (axSpA).

20 Feb 2013

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

Microbes present in the gut can affect the severity of kidney disease brought on by melamine poisoning, according to an international study led by Professor Wei Jia at the University of North Carolina in collaboration with the research group of Professor Jeremy Nicholson at Imperial College London.

16 Feb 2013

More people meeting recommended goals in three key markers of diabetes control

More people are meeting recommended goals in the three key markers of diabetes control, according to a study conducted and funded by the National Institutes of Health and the Centers for Disease Control and Prevention.

16 Feb 2013

Symposium to discuss new techniques for assessing risk of acute kidney injury

Leading critical care experts will discuss new techniques for assessing risk of acute kidney injury (AKI) at an educational symposium to be held at the Eighteenth International Conference on Continuous Renal Replacement Therapies (CRRT) in San Diego.

11 Feb 2013

Diet high in fruits and vegetables may help protect kidneys of patients with CKD

Adding fruits and vegetables to the diet may help protect the kidneys of patients with chronic kidney disease (CKD) with too much acid build-up, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

10 Feb 2013

Single gene therapy session can cure diabetes

Researchers from the Universitat Aut-noma de Barcelona (UAB), led by F-tima Bosch, have shown for the first time that it is possible to cure diabetes in large animals with a single session of gene therapy. As published this week in Diabetes, the principal journal for research on the disease, after a single gene therapy session, the dogs recover their health and no longer show symptoms of the disease.

10 Feb 2013

Allopurinol may improve CV outcomes in kidney disease

The xanthine oxidase inhibitor allopurinol appears to be beneficial in preventing cardiovascular morbidity and all-cause mortality in patients with hypertensive nephropathy, show findings from a Japanese study.

8 Feb 2013

Tumor necrosis factor receptor 2 involved in renal decline in diabetes

Researchers have found that circulating levels of tumor necrosis factor receptor 2 are independently associated with the development of chronic kidney disease in nonobese Japanese patients with Type 2 diabetes.

8 Feb 2013

eGFR ‘powerful’ operative risk gauge

Patients’ estimated glomerular filtration rate is highly predictive of their risk for dying after surgery, shows a systematic review and meta-analysis.

8 Feb 2013

Scientists identify specific cellular events that appear key to lupus

A team led by scientists at The Scripps Research Institute (TSRI) has identified specific cellular events that appear key to lupus, a debilitating autoimmune disease that afflicts tens of millions of people worldwide. The findings suggest that blocking this pathway in lupus-triggering cells could be a potent weapon against the disease.

5 Feb 2013

Risk factors identified for renal abnormality in vesicoureteral reflux

Researchers have identified the main risk factors for renal functional abnormalities in children with high-grade vesicoureteral reflux.

4 Feb 2013

Hypertensive pregnancies need rigorous follow up

Women who have hypertensive complications during pregnancy are at increased risk for developing chronic kidney disease and end-stage renal disease, shows a study in the Canadian Medical Association Journal.

31 Jan 2013

CKD may raise risk of mortality and end stage renal disease for both men and women

A new study from the Johns Hopkins Bloomberg School of Public Health and the Chronic Kidney Disease Prognosis Consortium (CKD-PC) found that in general chronic kidney disease is similarly associated with a higher risk of death and end stage renal disease for both women and men. The findings were released online in advance of publication in BMJ.

31 Jan 2013

NSAIDs pose kidney risk in some children

A small but significant percentage of children develop acute kidney injury after taking nonsteroidal anti-inflammatory drugs such as ibuprofen, show study findings published in the Journal of Pediatrics.

29 Jan 2013

Minimally invasive islet transplantation reverses progression of atherosclerosis in type 1 diabetics

Minimally invasive islet transplantation for patients with type 1 diabetes achieves insulin independence and reverses the progression of atherosclerosis in the first few years after transplant, according to a University of Illinois at Chicago study.

29 Jan 2013

Viewpoints: Debating P4P; ‘Tactical retreat' by GOP; The virtues of across-the-board spending cuts

Instead of granting automatic pay increases, N.Y. City's public hospital system will pay them based on how well they reduce costs, increase patient satisfaction and improve the quality of care. The Health and Hospitals Corporation, which runs the city's 11 public hospitals, deserves praise for an ambitious proposal that will need to be refined as it is put into practice.

28 Jan 2013

Hypertensive pregnancies need rigorous follow up

28 Jan 2013

Takeda receives FDA approval for Nesina, Kazano and Oseni to treat type 2 diabetes

The U.S. Food and Drug Administration today approved three new related products for use with diet and exercise to improve blood sugar control in adults with type 2 diabetes: Nesina (alogliptin) tablets, Kazano (alogliptin and metformin hydrochloride) tablets, and Oseni (alogliptin and pioglitazone) tablets.

28 Jan 2013

Kidney disease increases risk of premature death in diabetic patients

One in every 10 Americans has diabetes, and a third or more of those with the condition will develop kidney disease. It may be possible to live a long and healthy life with diabetes, but once kidney disease develops, the risk of dying prematurely increases significantly, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

25 Jan 2013

Nephropathy News and Research

Further Reading

FDA approves new vial size for CSL Behring’s Privigen to treat primary immunodeficiency

UCB seeks FDA and EMA marketing authorization for Cimzia to treat active psoriatic arthritis

Gut microbes can affect severity of kidney disease brought on by melamine poisoning

More people meeting recommended goals in three key markers of diabetes control

Symposium to discuss new techniques for assessing risk of acute kidney injury

Diet high in fruits and vegetables may help protect kidneys of patients with CKD

Single gene therapy session can cure diabetes

Allopurinol may improve CV outcomes in kidney disease

Tumor necrosis factor receptor 2 involved in renal decline in diabetes

eGFR ‘powerful’ operative risk gauge

Scientists identify specific cellular events that appear key to lupus

Risk factors identified for renal abnormality in vesicoureteral reflux

Hypertensive pregnancies need rigorous follow up

CKD may raise risk of mortality and end stage renal disease for both men and women

NSAIDs pose kidney risk in some children

Minimally invasive islet transplantation reverses progression of atherosclerosis in type 1 diabetics

Viewpoints: Debating P4P; ‘Tactical retreat' by GOP; The virtues of across-the-board spending cuts

Hypertensive pregnancies need rigorous follow up

Takeda receives FDA approval for Nesina, Kazano and Oseni to treat type 2 diabetes

Kidney disease increases risk of premature death in diabetic patients

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