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GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A patient with relapsed T cell leukemia has been given base-edited T-cells in a world-first use of a base-edited cell therapy, in a 'bench-to-bedside' collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

12 Dec 2022

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

Investigators from Rutgers Cancer Institute of New Jersey, the state's only NCI-designated Comprehensive Cancer Center and leading cancer program along with Tufts Medical Center in Boston, developed and validated the Advanced-stage Hodgkin lymphoma International Prognostication Index (A-HIPI).

12 Dec 2022

For patients with sickle cell disease, fertility care is about reproductive justice

Teonna Woolford has always wanted six kids. Why six? "I don't know where that number came from. I just felt like four wasn't enough," said Woolford, a Baltimore resident. "Six is a good number."

8 Dec 2022

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

The Ajmera Transplant Centre at University Health Network (UHN) has performed a groundbreaking parathyroid transplant, in a patient who suffered from a severe form of hypoparathyroidism – when there is little or no parathyroid function.

5 Dec 2022

Study: 40% of websites for heart transplant centers lack information in languages other than English

In a University of Michigan-led study, researchers found that most websites for heart transplant centers in the United States are difficult to understand, with more than 40% lacking information in languages other than English.

30 Nov 2022

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

Recently, scientists reviewed the role of sulforaphane from cruciferous vegetables (e.g., broccoli) in preventing IBD by regulating inflammation and altering the gut microbiome.

29 Nov 2022

World Antimicrobial Awareness Week 2022: What is the burden of antimicrobial resistance?

As part of World Antimicrobial Resistance Week 2022, News-Medical speaks to Dr. Tomislav Meštrović about his new research discussing the burden of bacterial antimicrobial resistance in the WHO European region, as well as about how we can prevent antimicrobial resistance together.

24 Nov 2022

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

A third COVID-19 vaccine dose in this patients with blood cancers could enhance their antibody responses against SARS-CoV-2

21 Nov 2022

Rutgers scientists develop new approach to effectively shut down viral infections

Rutgers scientists have developed a new approach to stopping viral infections: a so-called live-attenuated, replication-defective DNA virus vaccine that uses a compound known as centanamycin to generate an altered virus for vaccine development.

20 Nov 2022

Caregivers’ coping strategies affect their level of distress and quality of life

November is Caregiver Awareness Month, and timely findings from a study published in Blood Advances suggest that, among caregivers of patients undergoing a stem cell transplant, how someone approaches coping can influence their levels of anxiety, depression, and poor quality of life (QOL) they experience.

20 Nov 2022

IESC transplant could repair the intestinal barrier after stroke and improve outcomes

Stroke is a leading cause of death, dementia and serious long-term disability. According to the American Heart Association, stroke patients also have a greater risk of depression, which negatively affects functional and cognitive recovery.

20 Nov 2022

Study analyzes left digit bias in organ donors entering a new decade of age

American transplant centers as well as organ procurement organizations, the groups responsible for recovering organs from deceased donors in the United States, were less likely to accept or select organs from donors who were 70 years old when they died compared to those who were 69, new research found.

17 Nov 2022

Scientists develop new injectable hydrogel for treatment of aneurysms

Aneurysms, abnormal enlargement or ballooning in the wall of blood vessels can result in rupture and fatal bleeding. To treat aneurysms, it is essential to stop the blood flow to the affected area and prevent rupture of the vessel.

16 Nov 2022

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Cambridge scientists have used synthetic biology to create artificial enzymes programmed to target the genetic code of SARS-CoV-2 and destroy the virus, an approach that could be used to develop a new generation of antiviral drugs.

16 Nov 2022

Pancreas transplant more beneficial than other treatments for people with diabetes

Results of pancreas transplantation continue to improve and up to 90% of recipients with diabetes enjoy freedom from both insulin therapy and the need for close glucose monitoring following the procedure, according to a new paper published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

15 Nov 2022

Study demonstrates unexpected electrical changes in first successful transplant of genetically-modified pig heart

Ten months after transplanting the first genetically-modified pig heart into a human patient, University of Maryland School of Medicine researchers continue to report on new findings from the landmark transplant.

14 Nov 2022

Research reveals why stem cell transplants are so successful in MS patients

Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study led by the University of Zurich has now examined in detail the way in which the treatment curbs the autoimmune disease and how the immune system regenerates afterwards.

10 Nov 2022

Transplant News and Research

GOSH delivers world-first base-edited cell therapy for a patient with relapsed T cell leukemia

A-HIPI decision model can predict survival in adults with advanced-stage Hodgkin lymphoma

For patients with sickle cell disease, fertility care is about reproductive justice

UHN’s Ajmera Transplant Centre performed a groundbreaking parathyroid transplant

Study: 40% of websites for heart transplant centers lack information in languages other than English

Broccoli and sprouts improve gut microbiota and reduce inflammation in IBD

World Antimicrobial Awareness Week 2022: What is the burden of antimicrobial resistance?

Additional mRNA COVID vaccine doses could salvage antibody responses in blood cancer patients

Rutgers scientists develop new approach to effectively shut down viral infections

Caregivers’ coping strategies affect their level of distress and quality of life

IESC transplant could repair the intestinal barrier after stroke and improve outcomes

Study analyzes left digit bias in organ donors entering a new decade of age

Scientists develop new injectable hydrogel for treatment of aneurysms

Cambridge scientists use synthetic biology approach to destroy SARS-CoV-2 virus

Pancreas transplant more beneficial than other treatments for people with diabetes

Study demonstrates unexpected electrical changes in first successful transplant of genetically-modified pig heart

Research reveals why stem cell transplants are so successful in MS patients

First transfusions of lab-grown blood

Pioneering research identifies a promising treatment approach for myelofibrosis

Terasaki Innovation Summit to focus on improving technological, entrepreneurial translation of personalized medicines

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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