Enzyme News and Research

RSS

UCR professor to better organize enzymes on electrodes to create nanoscale devices

An assistant professor at the University of California, Riverside's Bourns College of Engineering has recently received a $360,000 grant to better organize enzymes on electrodes to create nanoscale devices that more efficiently convert the chemical energy of sugars and complex carbohydrates in to electricity.

8 Mar 2013

Vitamin B12 and folate alleviate negative symptoms in patients with schizophrenia

Adding the dietary supplements folate and vitamin B12 to treatment with antipsychotic medication improved a core symptom component of schizophrenia in a study of more than 100 patients.

7 Mar 2013

Scientists discover key biochemical step underlying heart failure

Some 5.8 million Americans suffer from heart failure, a currently incurable disease. But scientists at Temple University School of Medicine's (TUSM) Center for Translational Medicine have discovered a key biochemical step underlying the condition that could aid the development of new drugs to treat and possibly prevent it.

6 Mar 2013

Study shows how high shear stress could cause VWF to change shape and form blood clots

New research from Rice University, Baylor College of Medicine (BCM) and the Puget Sound Blood Center (PSBC) has revealed how stresses of flow in the small blood vessels of the heart and brain could cause a common protein to change shape and form dangerous blood clots.

6 Mar 2013

KMO gene variant associated with increased production of kynurenic acid

Researchers at Karolinska Institutet in Sweden have found an explanation for why the level of kynurenic acid (KYNA) is higher in the brains of people with schizophrenia or bipolar disease with psychosis. The study, which is published in the scientific periodical Molecular Psychiatry, identifies a gene variant associated with an increased production of KYNA.

5 Mar 2013

Researchers map links between human genome, metabolism

An international team of researchers, including an investigator with the Virginia Bioinformatics Institute at Virginia Tech, has produced what may be the most comprehensive computer model of human metabolism yet developed.

5 Mar 2013

OPKO Health acquires Cytochroma

OPKO Health, Inc. announced that it has completed the acquisition of Cytochroma Inc. Cytochroma's lead products include CTAP101 Capsules, a vitamin D prohormone to treat secondary hyperparathyroidism (SHPT) in patients with stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency, and Fermagate Tablets, a new and potent non-absorbed phosphate binder to treat hyperphosphatemia in CKD patients on chronic hemodialysis.

4 Mar 2013

Scientists produce new instruction manual for human genome

Scientists have produced an instruction manual for the human genome that provides a framework to better understand the relationship between an individual's genetic make-up and their lifestyle.

From The University of Manchester 4 Mar 2013

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered how the most common genetic mutations in familial Parkinson's disease damage brain cells.

4 Mar 2013

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

In an article published as the cover story of the March 2013 issue of Nature Chemical Biology, Lindsey James, PhD, research assistant professor in the lab of Stephen Frye, Fred Eshelman Distinguished Professor in the UNC School of Pharmacy and member of the UNC Lineberger Comprehensive Cancer Center, announced the discovery of a chemical probe that can be used to investigate the L3MBTL3 methyl-lysine reader domain.

3 Mar 2013

Clothing closely linked to peak performance for skiers

The sport of cross-country skiing has always been preoccupied with its skis and waxing. Research now demonstrates that to shave off those extra hundredths of a second, competitive skiers should pay more attention to their clothing.

3 Mar 2013

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Max Planck scientists in Jena, Germany, have discovered an unusual regulation of enzymes that catalyze chain elongation in an important secondary metabolism, the terpenoid pathway.

2 Mar 2013

Study shows triple-negative breast cancer cells missing key enzyme

A groundbreaking new study led by the University of Kentucky Markey Cancer Center's Dr. Peter Zhou found that triple-negative breast cancer cells are missing a key enzyme that other cancer cells contain - providing insight into potential therapeutic targets to treat the aggressive cancer.

2 Mar 2013

Eye-rubbing may provoke, aggravate keratoconus

Rubbing the eyes leads to an increase in protease activity and levels of protease and inflammatory mediators, a clinical study shows.

1 Mar 2013

Researchers discover unrecognized mechanism by which PI3K sustains proliferation of cancer cells

New research published today in the Biochemical Journal describes the discovery of a new cancer target.

28 Feb 2013

EpiCept fourth quarter revenue decreases to $0.1 million

EpiCept Corporation today announced operating and financial results for the fourth quarter and full year ended December 31, 2012, and provided an update on the Company's merger with Immune Pharmaceuticals, Ltd. (Immune).

28 Feb 2013

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

According to a recent University of Eastern Finland (UEF) study, elevated cell sugar concentrations increase the production of hyaluronan which, in turn, promotes cancer growth. Regulating the production of hyaluronan may be a way to prevent the spreading of cancer.

28 Feb 2013

Viewpoints: Former Sen. Gramm criticizes Obama on budget cuts; Debate on revamping Medicare needs less heat, more deliberation

While history shows that a divided government can enact significant spending cuts as an alternative to sequesters, that doesn't appear to be the path Mr. Obama intends to follow. Instead of protecting civilian defense workers, the president will continue to force the Pentagon to buy biofuels at $27 per gallon to promote his green agenda.

27 Feb 2013

Experts analyse biological function of Shewanella-like protein phosphatase

Experts have disabled a unique member of the signalling proteins which are essential for the development of the malaria parasite. They have produced a mutant lackingthe ancient bacterial Shewanella-like protein phosphatase known as SHLP1 (pronounced shelph). This mutant is unable to complete its complex life cycle and is arrested in its development in the mosquito.

26 Feb 2013

New research examines role of PKC in airway smooth muscle contraction

New research examines the role of PKC in airway smooth muscle contraction and raises the possibility that this enzyme could be a therapeutic target for treating asthma, COPD, and other lung diseases.

26 Feb 2013

Enzyme News and Research

UCR professor to better organize enzymes on electrodes to create nanoscale devices

Vitamin B12 and folate alleviate negative symptoms in patients with schizophrenia

Scientists discover key biochemical step underlying heart failure

Study shows how high shear stress could cause VWF to change shape and form blood clots

KMO gene variant associated with increased production of kynurenic acid

Researchers map links between human genome, metabolism

OPKO Health acquires Cytochroma

Scientists produce new instruction manual for human genome

Researchers discover how LRRK2 mutations in familial Parkinson's damage brain cells

UNC1215 chemical probe can help investigate L3MBTL3 methyl-lysine reader domain

Clothing closely linked to peak performance for skiers

Scientists discover enzyme regulation that catalyzes chain elongation in the terpenoid pathway

Study shows triple-negative breast cancer cells missing key enzyme

Eye-rubbing may provoke, aggravate keratoconus

Researchers discover unrecognized mechanism by which PI3K sustains proliferation of cancer cells

EpiCept fourth quarter revenue decreases to $0.1 million

Elevated cell sugar concentrations increase hyaluronan production and promote cancer growth

Viewpoints: Former Sen. Gramm criticizes Obama on budget cuts; Debate on revamping Medicare needs less heat, more deliberation

Experts analyse biological function of Shewanella-like protein phosphatase

New research examines role of PKC in airway smooth muscle contraction

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo