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Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

A pioneering new study led by UCL and National Institutes of Health (NIH) scientists has revealed, for the first time, why a common genetic variant worsens disease outcomes for people with the devastating adult-onset neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

24 Feb 2022

New studies explore the potential role of bariatric surgery in reducing breast cancer risk

New studies aim to clarify the relationship between obesity and breast cancer, and explore the potential role of bariatric surgery in reducing this risk, according to a review published online in Obesity, The Obesity Society's flagship journal.

23 Feb 2022

Study on Omicron related mortality in cancer patients during recent COVID wave

A recent pre-proof study published in the journal Cancer Cell assessed the CFR of cancer patients during the third wave of the coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 Omicron variant.

23 Feb 2022

Researchers explore possible use of stress reduction in atrial fibrillation management

Stress has been linked with poor health outcomes, though the exact mechanism remains poorly defined. Psychological stress is recognized as a contributing factor in atrial fibrillation (AFib), both in initiation and heightening of AFib.

23 Feb 2022

Discovery of signaling pathway in immune cells may lead to new therapeutic approach for autoimmune diseases

Autoimmune diseases are triggered when the immune system malfunctions and attacks the body's own structures.

23 Feb 2022

Nearly 1% of all US adults prescribed opioids are also taking various other sedatives

As many as 2.6 million Americans—equivalent to 1 per cent of all US adults —prescribed opioids are also taking various other sedatives, including benzodiazepines plus another type of sedative drug, estimates research published online in the journal Regional Anesthesia & Pain Medicine.

23 Feb 2022

Merkel cell carcinoma has a higher post-treatment recurrence rate than other skin cancers

Patients treated for Merkel cell carcinoma (MCC) face a five-year recurrence rate of 40% - markedly higher than the recurrence rates for melanoma and other skin cancers, according to research published today in JAMA Dermatology.

23 Feb 2022

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

A new drug, administered in combination with standard androgen-deprivation therapy and docetaxel chemotherapy, increased survival in patients with metastatic hormone-sensitive prostate cancer, according to a trial published in The New England Journal of Medicine.

23 Feb 2022

Cardiopulmonary limitations six months after surviving COVID-19

A recent prospective cohort study assessed the cardiopulmonary effects in patients six months after COVID-19 infection.

23 Feb 2022

Why is it Important to Democratize Proteomics Data?

In this interview, we speak to Steve Kosteski from IsoPlexis about the importance of single-cell proteomics within the life sciences sector.

From Society for Laboratory Automation and Screening (SLAS) 23 Feb 2022

Gene therapy leads to durable transfusion independence in youngest patients with thalassemia

Over 90 percent of patients with transfusion-dependent thalassemia, an inherited blood disorder, no longer needed monthly blood transfusions years after receiving gene therapy, according to an international Phase 3 clinical trial that for the first time included children younger than 12 years of age.

22 Feb 2022

Novel platform can become a potential approach for personalized cancer treatments

Killing cancer cells without affecting surrounding normal cells is the most desirable approach for targeted cancer therapy. However, it cannot be easily achieved due to the similarities in the properties between normal and cancer cells.

22 Feb 2022

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Multiple myeloma (MM) is a largely incurable cancer of plasma cells with an extremely poor prognosis. However, investigators from Japan have recently found that a common component of amino acid transporters, CD98 heavy chain, represents an effective monoclonal antibody target in treating MM.

22 Feb 2022

Study offers a new, effective therapeutic option against glioblastoma

A study recently accepted for publication in The Journal of Clinical Investigation describes a new and effective therapy to treat glioblastoma: the concomitant use of ADI-PEG20 together with focal brain radiotherapy.

22 Feb 2022

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Researchers demonstrated the potent neutralization of SARS-CoV-2 VOCs, including Omicron by the biparatopic human heavy chain variable domain.

22 Feb 2022

Time-based sensitivity of COVID-19 serological testing

In a recent study under consideration at Scientific Reports and posted to the Research Square* preprint server, researchers evaluated the impact of time on the sensitivity of four severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) serological assays using samples from the coronavirus disease 2019 (COVID-19) staff testing of antibody responses study(Co-Stars) in the United Kingdom (UK).

22 Feb 2022

Researchers discover how pre-transplant chemotherapy facilitates the replacement of microglial cells

More than 50,000 bone marrow-derived stem cell transplants are performed worldwide each year to treat a wide range of conditions, including brain diseases.

21 Feb 2022

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Researchers at The University of Texas MD Anderson Cancer Center have developed a new radio-labeled molecule capable of selectively reacting with certain high-energy radicals that are characteristic of innate immune activity, which may allow a non-invasive approach to monitor inflammation in real time by positron emission tomography (PET) imaging.

21 Feb 2022

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

Researchers identify 87G7, a SARS-CoV-2 neutralizing human monoclonal antibody with remarkable broad-spectrum neutralization and protection efficacy.

21 Feb 2022

Analysis reveals the truth about FDA's expedited approval processes and patient access

University of Illinois Chicago researchers studied 135 products that received U.S. Food and Drug Administration approval through orphan drug and expedited approval program designations.

21 Feb 2022

Therapy News and Research

Research reveals why a common genetic variant worsens outcomes for people with ALS and FTD

New studies explore the potential role of bariatric surgery in reducing breast cancer risk

Study on Omicron related mortality in cancer patients during recent COVID wave

Researchers explore possible use of stress reduction in atrial fibrillation management

Discovery of signaling pathway in immune cells may lead to new therapeutic approach for autoimmune diseases

Nearly 1% of all US adults prescribed opioids are also taking various other sedatives

Merkel cell carcinoma has a higher post-treatment recurrence rate than other skin cancers

New combination treatment strategy for managing metastatic hormone-sensitive prostate cancer

Cardiopulmonary limitations six months after surviving COVID-19

Why is it Important to Democratize Proteomics Data?

Gene therapy leads to durable transfusion independence in youngest patients with thalassemia

Novel platform can become a potential approach for personalized cancer treatments

New approach for extensive screening of monoclonal antibody clones against multiple myeloma cells

Study offers a new, effective therapeutic option against glioblastoma

Study provides a potent biparatopic antibody against all SARS-CoV-2 variants of concern

Time-based sensitivity of COVID-19 serological testing

Researchers discover how pre-transplant chemotherapy facilitates the replacement of microglial cells

New radio-labeled molecule may allow a non-invasive approach to monitor inflammation in real time

Novel ACE2-blocking antibody protects against all SARS-CoV-2 VOCs

Analysis reveals the truth about FDA's expedited approval processes and patient access

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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