Immune System News and Research

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Night shifts may have negative impact on long-term health

A team of researchers from the McGill University affiliated Douglas Mental Health University Institute (DMHUI) has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns and that most of them stay tuned to their daytime biological clock rhythms.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

Study identifies molecule that may be critical to repair of white matter

A new study identifies a molecule that may be critical to the repair of white matter, the fatty tissue wrapped around parts of brain cells that helps speed up communication. Damage to white matter is associated with several conditions, including multiple sclerosis and cerebral palsy, and can occur in the brains of preterm babies.

7 May 2018

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Erythropoietin helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so.

7 May 2018

Researchers uncover protein linked to breast cancer metastasis

Jean-François Côté, a researcher at the Montreal Clinical Research Institute and professor at Université de Montréal's Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an aggressive type of cancer, HER2-positive breast cancer.

7 May 2018

Stimulant use may negatively affect health of HIV-positive persons

A researcher at the University of Miami Miller School of Medicine has found that the use of stimulants, such as methamphetamine, can negatively affect the health of HIV-positive persons even when they are adhering to medical treatment.

4 May 2018

New research illustrates how beneficial bacteria establish robust gut colonization

The mammalian gut is warm, moist, and incredibly nutrient-rich--an environment that is perfect for bacterial growth. The communities of "good bacteria" in the gut, commonly referred to as the microbiome, are vital partners for the body, helping to digest fiber, extract nutrients, and prevent various diseases.

4 May 2018

Frequent sauna baths linked to lower stroke risk

Frequent sauna bathing is associated with a reduced risk of stroke, according to a new international study. In a 15-year follow-up study, people taking a sauna 4-7 times a week were 61% less likely to suffer a stroke than those taking a sauna once a week.

4 May 2018

UTSW study provides insight into potential new therapeutic approaches for skin diseases

Research at UT Southwestern has shown that targeting metabolism in growing cells holds promise for the treatment of skin diseases like psoriasis that are characterized by skin overgrowth resulting from excess cell division, known as hyperproliferation.

4 May 2018

Stiff tissue can present microenvironment susceptible to tumor growth, says study

Stiffer breast tissue creates an environment more prone to cancer by enabling the disease to interfere with the surrounding healthy cells, according to a recent study published in Biomaterials.

4 May 2018

Ocular oncologists link immunotherapy with potentially vision-robbing side effect

New immunotherapy treatments offer a remarkable chance for survival for patients with advanced melanoma and hard-to-treat cancers of the bladder, kidney and lung.

4 May 2018

Genes that control the immune system may play role in hair graying

A study has found a link between genes that warn our bodies of a pathogenic infection and genes that play a role in determining hair color.

4 May 2018

Study shows how bacterial toxins can cripple normal cellular activity

Bacterial toxins can wreak mass havoc within cells by shutting down multiple essential functions at once, a new study has found.

4 May 2018

Cancer Center at BIDMC announces launch of new Immunotherapy Institute

The Cancer Center at Beth Israel Deaconess Medical Center today announced the launch of a new clinical and research institute that will build on BIDMC's long history of leadership in immunotherapy and cell therapeutics.

3 May 2018

Study points to new treatments for incurable bowel conditions

Treatments for incurable bowel conditions may be a step closer following the discovery of a key molecule associated with disease flare-ups.

3 May 2018

Mother's milk found to have SWAT team of immune cells

Immune cells that are ready to take action against invaders like bacteria have been found in women's breast milk, researchers say.

3 May 2018

Circulating immune cells found to worsen, rather than improve heart disease

New research led by investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center suggests that the location of immune cells in the body determines whether they help or harm the development of heart disease.

3 May 2018

Study uncovers unconventional killer T cells capable of combating viral infections

Research led by the University of Birmingham has identified a novel unconventional type of immune cell capable of fighting viral infections.

2 May 2018

New vaccine strategy increases number of tumor-specific cancer-killing T cells

New research published in Cancer Immunology Research by Drs. Esteban Celis and Hussein Sultan of the Georgia Cancer Center at Augusta University could serve as the stepping-stone in constructing vaccines with a greater likelihood of finding and attacking tumors in the human body.

2 May 2018

Immune System News and Research

Night shifts may have negative impact on long-term health

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Study identifies molecule that may be critical to repair of white matter

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Researchers uncover protein linked to breast cancer metastasis

Stimulant use may negatively affect health of HIV-positive persons

New research illustrates how beneficial bacteria establish robust gut colonization

Frequent sauna baths linked to lower stroke risk

UTSW study provides insight into potential new therapeutic approaches for skin diseases

Stiff tissue can present microenvironment susceptible to tumor growth, says study

Ocular oncologists link immunotherapy with potentially vision-robbing side effect

Genes that control the immune system may play role in hair graying

Study shows how bacterial toxins can cripple normal cellular activity

Cancer Center at BIDMC announces launch of new Immunotherapy Institute

Study points to new treatments for incurable bowel conditions

Mother's milk found to have SWAT team of immune cells

Circulating immune cells found to worsen, rather than improve heart disease

Study uncovers unconventional killer T cells capable of combating viral infections

New vaccine strategy increases number of tumor-specific cancer-killing T cells

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