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Cleveland Clinic researchers identify novel target for anti-fibrotic therapies

In a new study published in Science Signaling, Cleveland Clinic researchers have identified a novel target for new therapies that may help to treat or prevent a host of fibrotic conditions, which contribute to nearly half of overall mortality in the United States.

13 Nov 2019

Researchers find mechanism that controls the growth of B1-cells

Directly after birth, the immune system completes production of a subtype of antibody-producing immune cells, B-1, that are to last for a lifetime. No more B1-cells are formed after that point. However, these cells are self-reactive - they produce not only antibodies against foreign substances, but also against the body's own substances, and it is unclear why the immune system allows for the development of these particular cells.

13 Nov 2019

New IASLC policy statement discourages the use of e-cigarettes by non-smokers

The IASLC is the world's largest multidisciplinary lung cancer organization and the new policy statement coincides with Lung Cancer Awareness Month.

13 Nov 2019

Researchers take major step towards developing a viable vaccine for malaria

Researchers have narrowed down the malaria proteins and disease-fighting antibodies that could be used to develop a vaccine against the most severe forms of malaria.

13 Nov 2019

Doctors issue stern warning on e-cigarette use as it can damage vital organs

E-cigarette use has increased dramatically over the last decade. With its popularity, the use of e-cigarette spans from adolescents to adults. Now, cardiologists warn against the use of e-cigarettes and how these devices cause damage to vital organs, including the heart, brain, lungs, and blood vessels.

12 Nov 2019

Cardiac resynchronization therapy improves heart function in cancer survivors

A pacemaker-like device restored heart function in a group of cancer survivors -- mostly women with breast cancer -- who had suffered from heart failure as a result of chemotherapy treatment, a study in the Journal of the American Medical Association reports.

12 Nov 2019

Standard methods not adequate to detect prosthetic joint infections in rheumatic disease patients

Standard diagnostic methods are not adequate to identify prosthetic joint infections in patients with rheumatic diseases, according to findings from a new study by researchers from Hospital for Special Surgery in New York City.

12 Nov 2019

Study finds vitamin B12 deficiency in pregnancy may induce obesity

A new study which was presented at the annual conference of Society for Endocrinology reports that vitamin B12 deficiency could disrupt the normal metabolism of fat and could indirectly contribute to weight gain and obesity in pregnancy. This emphasizes the need supplement this vitamin during pregnancy, because obesity in pregnancy is linked to a number of adverse health outcomes over the long term, including diabetes.

12 Nov 2019

Medical steroid use could push up diabetes risk

Glucocorticoids (GCs), or steroids, as they are popularly called, are often prescribed for their anti-inflammatory effects in a host of conditions including acute asthmatic attacks, allergies, and arthritis. However, are they doing good or harm?

12 Nov 2019

Lung inflammation in a case of a 16-year-old linked to vaping

The Centre for Disease Control and Prevention (CDC) has warned earlier last month about the possible risk of lung inflammation from the exposure to the fluid in e-cigarettes. Now a case of a 16-year-old boy was reported with life threatening lung inflammation leading to respiratory failure.

12 Nov 2019

High muscle volume in middle age tied to lower cardiovascular disease risk

Middle-aged adults who have more muscle mass have decreased cardiovascular disease, a new study suggests.

12 Nov 2019

White blood cells control final moments of their death

La Trobe University researchers have revealed for the first time how white blood cells control the final moments of their death, helping their own removal from the human body.

12 Nov 2019

Autoimmune attack on uninfected red blood cells may cause anemia in malaria patients

An autoimmune attack on uninfected red blood cells likely contributes to anaemia - a shortage of red blood cells - in people with malaria, according to a new study published in eLife.

12 Nov 2019

Virginia Tech professor wins $1.85 million NIH grant for sepsis research

One drop of blood contains 5,000 neutrophils, the most abundant type of white blood cell that is deployed by the human immune system. Throughout the entire body, a human has 25 billion of these foot soldiers that are relentlessly patrolling to fight invading pathogens.

12 Nov 2019

Cardiac-specific biomarkers may help predict CVD risk factors early

A new review article provides valuable insights into how traditional and emerging cardiac-specific biomarkers and their associated cardiovascular disease (CVD) risk factors may help point to effective preventive interventions in high-risk obese populations starting at an early stage of disease development.

12 Nov 2019

Depression in middle and older adulthood associated with nutrition

Your diet can put you at risk of depression, according to a new study. The study also found that the likelihood of depression is higher among middle-aged and older women who were immigrants to Canada when compared to Canadian-born women.

12 Nov 2019

Regulating gut bacteria could calm chemo side effects, reduce cognitive problems

In a new study, scientists observed several simultaneous reactions in mice given a common chemotherapy drug: Their gut bacteria and tissue changed, their blood and brains showed signs of inflammation, and their behaviors suggested they were fatigued and cognitively impaired.

11 Nov 2019

Juvenile immune arthritis – new treatments wanted

Juvenile immune arthritis (JIA) is a severely undertreated condition, and new medications are badly needed to relieve the signs and symptoms of the illness, according to a new study presented at the 2019 ACR/ARP Annual Meeting.

11 Nov 2019

Methotrexate reduces joint damage in hand osteoarthritis

A new study presented at the 2019 ACR/ARP meeting shows that methotrexate stopped further damage to the hand joints and even perhaps improved bone remodeling in patients with osteoarthritis (OA) of the hand, when they were assessed at 3 and 12 months.

11 Nov 2019

Rheumatoid arthritis: biologics useful in young and old alike

A new study presented at the 2019 ACR/ARP Annual Meeting says that all rheumatoid arthritis (RA) patients, irrespective of their age, benefit to a similar extent from the use of biologic drugs in their treatment. The study measured improvement in disease parameters 48 weeks after the beginning of therapy to establish this conclusion.

11 Nov 2019