Immune System News and Research

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Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

A Delaware team including Erin Crowgey, PhD, associate director of Bioinformatics with Nemours Biomedical Research, has published a study in the peer-reviewed journal BMC Bioinformatics, showing that DNA patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients.

22 Jun 2018

New study reveals how ‘good’ bacteria help in regulating our metabolism

Research tells us that the commensal or "good" bacteria that inhabit our intestines help to regulate our metabolism.

22 Jun 2018

Novel cellular pathway may clarify how arterial inflammation develops into atherosclerosis

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis - deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide.

22 Jun 2018

Scientists discover the molecular trigger of necroptosis

Researchers have uncovered a trigger for an immune-related cell death pathway called necroptosis. The discovery could be used to develop new treatments for cancer and immune disorders.

21 Jun 2018

Protein Data Bank at Rutgers impacts research, education and drug discovery

When Jimmy Carter was diagnosed with end-stage metastatic melanoma in 2015, he began taking a drug developed in part using 3D molecular data.

21 Jun 2018

Fetal immune cells are fast-acting first responders to microbes in adulthood

Cornell University researchers have discovered there is a division of labor among immune cells that fight invading pathogens in the body.

20 Jun 2018

UT Southwestern scientists identify gene mutation linked with perplexing brain condition

Scientists conducting one of the largest full DNA analyses of a rare disease have identified a gene mutation associated with a perplexing brain condition that blinds and paralyzes patients.

20 Jun 2018

Biosimilar competition may offer hope for cheaper, better psoriasis treatments in the future

A new study by iData Research estimates that there are nearly 150,000 new cases of psoriasis every year in the United States, affecting 2.2% of the population.

20 Jun 2018

Researchers use advanced technology to identify proteomes of Th17 and iTreg cells

T helper 17 (Th17) cells belong to a group of T cells with essential functions in autoimmune diseases and inflammation. Regulatory T cells (iTregs) are T cells with a suppressive function to maintain self-tolerance and prevent autoimmune responses.

20 Jun 2018

Monash study reveals why older people have reduced immune responses to cancer therapy

It's called the Silver Tsunami - the increased incidence of cancer with aging, combined with the rapidly aging population means that the Australian health system needs to prepare for an onslaught of cancer diagnoses.

20 Jun 2018

Study provides new insight on how antibiotics affect the gut microbiome

New insight on how antibiotics affect the gut microbiome - the community of microbes that live inside us - has been published in the journal eLife.

19 Jun 2018

Scientists discover new mechanism controlling multiple sclerosis risk

While the DNA sequence remains the same throughout a person's life, the expression of the encoded genes may change with time and contribute to disease development in genetically predisposed individuals.

19 Jun 2018

Low blood levels of vitamin D linked to increased risk of interstitial lung disease

Reviewing medical information gathered on more than 6,000 adults over a 10-year period, Johns Hopkins researchers have found that lower than normal blood levels of vitamin D were linked to increased risk of early signs of interstitial lung disease.

19 Jun 2018

Clinical trial targets metastatic colorectal cancer with new combination therapy

Rutgers Cancer Institute of New Jersey is offering a clinical trial targeting an advanced form of colorectal cancer with a combination vaccine/immunotherapy drug treatment.

19 Jun 2018

Study: Rheumatoid Arthritis patients with depression have increased risk of disease flare

Research from the Department of Inflammation Biology, School of Immunology & Microbial Sciences has shown there is an increased risk of disease flare in Rheumatoid Arthritis patients who suffer from depression.

19 Jun 2018

CytoReason builds largest reference of immune-focused inter-cellular communications

New data published in Nature Biotechnology, represents the largest ever analysis of immune cell signaling research, mapping more than 3,000 previously unlisted cellular interactions, and yielding the first ever immune-centric modular classification of diseases.

19 Jun 2018

Researchers use droplet-sized 'miniecosystems' to test therapeutic potential of molecules

Scripps Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'miniecosystems' to quickly see if a molecule can function as a potential therapeutic.

19 Jun 2018

Researchers discover new defense mechanism against oxygen radicals

Oxygen radicals occur as a by-product when living beings burn carbohydrates or fat. They are suspected of accelerating the ageing process in humans and animals, and to be partly responsible for severe illnesses such as Alzheimer's or certain types of cancer.

18 Jun 2018

Immune System News and Research

Researchers discover immune profile for effective cancer immunotherapy

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

New study reveals how ‘good’ bacteria help in regulating our metabolism

Novel cellular pathway may clarify how arterial inflammation develops into atherosclerosis

Scientists discover the molecular trigger of necroptosis

Protein Data Bank at Rutgers impacts research, education and drug discovery

Fetal immune cells are fast-acting first responders to microbes in adulthood

UT Southwestern scientists identify gene mutation linked with perplexing brain condition

Biosimilar competition may offer hope for cheaper, better psoriasis treatments in the future

Researchers use advanced technology to identify proteomes of Th17 and iTreg cells

Monash study reveals why older people have reduced immune responses to cancer therapy

Study provides new insight on how antibiotics affect the gut microbiome

Scientists discover new mechanism controlling multiple sclerosis risk

Low blood levels of vitamin D linked to increased risk of interstitial lung disease

Clinical trial targets metastatic colorectal cancer with new combination therapy

Study: Rheumatoid Arthritis patients with depression have increased risk of disease flare

CytoReason builds largest reference of immune-focused inter-cellular communications

Researchers use droplet-sized 'miniecosystems' to test therapeutic potential of molecules

Researchers discover new defense mechanism against oxygen radicals

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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