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Oral steroids ineffective treatment for wheezing in children

A new study from Barts and The London School of Medicine and Dentistry has found that a common treatment for wheezing in preschool children is no more effective than a placebo.

21 Jan 2009

Anxious seniors may benefit from SSRIs

Many older adults worry - a lot. Almost one in 10 Americans over age 60 suffer from an anxiety disorder that causes them to worry excessively about normal things - like health, finances, disability and family.

21 Jan 2009

Cream containing tretinoin associated with death in clinical trial, but relationship does not appear causal

Patients using a cream containing tretinoin, a retinoid commonly used to treat acne and other conditions, appeared more likely to die than those using a placebo in a clinical trial that was halted early as a result, according to a report in the January issue of Archives of Dermatology.

19 Jan 2009

Savella - Fibromyalgia treatment approved by FDA

Forest Laboratories, Inc. and Cypress Bioscience, Inc. have announced that Savella (milnacipran HCl), a selective serotonin and norepinephrine dual reuptake inhibitor, was approved by the U.S. Food and Drug Administration (FDA) for the management of fibromyalgia.

19 Jan 2009

Depressed adolescents not harmed by being part of placebo group in clinical trial

In a national clinical trial, adolescents with moderate to severe depression first given a placebo treatment and then an antidepressant medication alone or in combination with therapy responded just as well over the long term as participants who received active treatment throughout the study, UT Southwestern Medical Center researchers report.

19 Jan 2009

Probiotics prevent IgE-associated allergy until age 5 in cesarean-delivered children but not in total cohort

According to a recent study from the University and the University Central Hospital of Helsinki, Finland, no allergy-preventive effect is extended to age 5 years by perinatal supplementation with probiotics in babies at risk for developing allergies; protection is conferred only to Cesarean section babies.

15 Jan 2009

Algeta completes phase II trial with Alpharadin for treating bone metastases in advanced prostate cancer

Algeta ASA has announced that with the results of the BC1-04 study reported today it has completed its comprehensive phase II clinical program evaluating Alpharadin (radium-223) as a new treatment for bone metastases in patients with hormone-refractory prostate cancer (HRPC).

15 Jan 2009

Numerical analysis estimates numbers of older US adults who may benefit from statin therapy

Researchers estimate more than 11 million older Americans may be newly eligible for statin therapy if findings from a recently published large clinical trial are adopted into clinical practice guidelines, according to a new analysis of the trial data.

13 Jan 2009

Certain fatty acids help neurodevelopment for preterm girls

Preterm infant girls who received a high amount of dietary docosahexaenoic acid (DHA; an omega-3 fatty acid) had higher measures of neurodevelopment than preterm girls who received a standard amount of DHA, but this effect was not seen among preterm boys, according to a study in the January 14 issue of JAMA.

13 Jan 2009

Pfizer joins URMC initiative for safety of experimental drugs

Pfizer Inc. has agreed to provide the University of Rochester Medical Center (URMC) with a unique set of electrocardiographic data that will help researchers develop new methods to ensure the safety of experimental drugs.

12 Jan 2009

An explanation of how statins cause low rates of muscle symptoms

In the January 2009 issue of the American Journal of Medicine , Florida Atlantic University researcher Charles H. Hennekens, M.D., the first Sir Richard Doll Research Professor in the Charles E. Schmidt College of Biomedical Science and a renowned expert who has revealed numerous causal, therapeutic and preventive factors in the treatment and prevention of cardiovascular disease (CVD), most notably low-dose aspirin, explains why statins cause low rates of muscle symptoms.

9 Jan 2009

Lilly receives complete response letter for Olanzapine LAI for treatment of schizophrenia

Eli Lilly and Company has announced that it received a complete response letter from the U.S. Food and Drug Administration (FDA) for olanzapine long-acting injection (LAI) for acute and maintenance treatment of schizophrenia in adults.

7 Jan 2009

Active Hexose Correlated Compound shown to enhances immune system by increasing production of key dendritic cells

A recently published study in Nutrition and Cancer (60(5), 643-651) by researchers at Kansai Medical University in Osaka, Japan has shown that AHCC (Active Hexose Correlated Compound) enhances immune function by increasing the number of dendritic cells (DCs).

6 Jan 2009

Nicotine gum effective for gradual smoking reduction and cessation

Nicotine gum has been in use for over 20 years to help smokers quit abruptly yet close to two-thirds of smokers report that they would prefer to quit gradually.

6 Jan 2009

Oxytocin hormone helps people recognize familiar faces

Oxytocin, a hormone involved in child-birth and breast-feeding, helps people recognize familiar faces, according to new research in the January 7 issue of The Journal of Neuroscience.

6 Jan 2009

Chimerix completes phase I study and starts phase II multi-dose trial for CMX001

Chimerix, Inc., a biotechnology company developing orally available antiviral therapeutics, has announced that the Company has completed a single and multi-dose Phase I study of CMX001 in healthy volunteers.

6 Jan 2009

Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial

Women who took beta carotene or vitamin C or E or a combination of the supplements had a similar risk of cancer as women who did not take the supplements, according to data from a randomized controlled trial in the December 30 online issue of the Journal of the National Cancer Institute.

1 Jan 2009

Candesartan shown to be safe new therapy for genetic heart disease

A new clinical trial suggests that long-term use of candesartan, a drug currently used to treat hypertension, may significantly reduce the symptoms of genetic heart disease.

1 Jan 2009

Researchers assess safety of bismuth compounds for treatment peptic ulcer disease

The discovery of H. pylori in 1983 led to renewed interest in bismuth compounds, because these were found to successfully treat the infection in combination with antibiotics. However, in the 1970s bismuth salts, used at high doses for prolonged periods, were found to lead to neurotoxicity.

1 Jan 2009

Antioxidant supplementation effective in relieving pain in chronic pancreatitis

Antioxidant supplementation was found to be effective in relieving pain and reducing levels of oxidative stress in patients with chronic pancreatitis (CP), reports a new study in Gastroenterology.

1 Jan 2009

Placebo News and Research

Oral steroids ineffective treatment for wheezing in children

Anxious seniors may benefit from SSRIs

Cream containing tretinoin associated with death in clinical trial, but relationship does not appear causal

Savella - Fibromyalgia treatment approved by FDA

Depressed adolescents not harmed by being part of placebo group in clinical trial

Probiotics prevent IgE-associated allergy until age 5 in cesarean-delivered children but not in total cohort

Algeta completes phase II trial with Alpharadin for treating bone metastases in advanced prostate cancer

Numerical analysis estimates numbers of older US adults who may benefit from statin therapy

Certain fatty acids help neurodevelopment for preterm girls

Pfizer joins URMC initiative for safety of experimental drugs

An explanation of how statins cause low rates of muscle symptoms

Lilly receives complete response letter for Olanzapine LAI for treatment of schizophrenia

Active Hexose Correlated Compound shown to enhances immune system by increasing production of key dendritic cells

Nicotine gum effective for gradual smoking reduction and cessation

Oxytocin hormone helps people recognize familiar faces

Chimerix completes phase I study and starts phase II multi-dose trial for CMX001

Vitamins C and E and beta carotene again fail to reduce cancer risk in randomized controlled trial

Candesartan shown to be safe new therapy for genetic heart disease

Researchers assess safety of bismuth compounds for treatment peptic ulcer disease

Antioxidant supplementation effective in relieving pain in chronic pancreatitis

Industry Focus eBook - Cell biology (5th edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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