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Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A novel combination treatment approach extended survival in mice with pancreatic cancer, demonstrating a potential second-line therapy for patients, according to findings published in Proceedings of the National Academy of Sciences.

15 Feb 2022

A third known case of HIV remission involving stem cell transplant documented

A woman with HIV who received a cord blood stem cell transplant to treat acute myeloid leukemia has had no detectable levels of HIV for 14 months despite cessation of antiretroviral therapy (ART), according to a presentation at today's Conference on Retroviruses and Opportunistic Infections (CROI).

15 Feb 2022

This doctor thought she could navigate US health care. Then her autistic son needed help.

Alexander Roodman was packing up his room, preparing for a gap year before college, when I met him at his family's Washington, D.C., townhouse.

15 Feb 2022

Regulating inflammation in Alzheimer's disease using a nanocleaner

In this new article publication from Acta Pharmaceutica Sinica B, authors Ting Lei, Zhihang Yang, Xue Xia, Yuxiu Chen, Xiaotong Yang, Rou Xie, Fan Tong, Xiaolin Wang, Huile Gao from Sichuan University, Chengdu, China and Macau University of Science and Technology, Macau, China discuss how nanocleaners can specifically penetrate the blood‒brain barrier at lesions to clean toxic proteins and regulate inflammation in Alzheimer's disease.

14 Feb 2022

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

A recent study posted to the bioRxiv* pre-print server investigated the antiviral potential of N-acylethanolamine acid amidase (NAAA) against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the Zika virus (ZIKV).

14 Feb 2022

Phase one study of oral SARS-CoV-2 antiviral agent nirmatrelvir

A recent study posted to the medRxiv* preprint server reported the phase one pharmacokinetic and safety data of nirmatrelvir/ritonavir to facilitate its rapid progression to the last stages of clinical trials in coronavirus disease 2019 (COVID-19) patients with mild to moderate disease.

14 Feb 2022

Studies compare endovascular therapy and microsurgery for treating wide-neck aneurysms

Aneurysms are weak, bulging portions of blood vessel walls. These blood-filled sacs resemble balloons in structure and have necks like balloons. Some aneurysms have larger necks and are called "wide-neck" aneurysms.

14 Feb 2022

Enhanced external counterpulsation therapy benefits long COVID-19 patients

In a small study of long COVID-19 patients, those with and without coronary artery disease demonstrated improvement of a variety of symptoms, including fatigue, breathing difficulties and chest discomfort, after undergoing 15-35 hours of enhanced external counterpulsation (EECP) therapy.

14 Feb 2022

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Researchers reported the development and validation of a two-reaction multiplex reverse transcription-quantitative polymerase chain reaction genotyping strategy that distinguishes SARS-CoV-2 variants of concern.

14 Feb 2022

Study identifies a link between mortality of newborns on ECMO and red blood cell transfusion volume

Newborns in respiratory failure who require the life-sustaining support of ECMO also require transfusion of red blood cells. But a new study indicates that the higher volume of these oxygen-carrying blood cells the babies receive, the higher their mortality rate.

14 Feb 2022

Researchers identify a powerful combination of antivirals to treat COVID-19

Researchers at the University of Maryland School of Medicine and University of Pennsylvania Perelman School of Medicine have identified a powerful combination of antivirals to treat COVID-19.

14 Feb 2022

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Researchers at the University of Toronto have identified hundreds of new proteins that could play a role in cystic fibrosis, and which may shed light on why some patients respond better than others to current therapies.

14 Feb 2022

Physicists investigate the usefulness of gene expression tests for cancer therapy

Following surgery, patients with breast cancer are faced with the question of whether additional chemotherapy is necessary and really effective.

14 Feb 2022

Novel tool for better dietary management in cancer patients

A new dietary tool to quickly and accurately assess micronutrient levels aims to help cancer patients fight disease, paving the way to find better nutritional solutions for oncology services, Flinders University researchers say.

14 Feb 2022

New research could deliver a breakthrough for kids suffering from severe form of genetic epilepsy

New research from the University of South Australia could deliver a breakthrough for children suffering one of the most severe forms of genetic epilepsy, reducing the frequency of their seizures and improving their quality of life.

14 Feb 2022

Nitazoxanide shows promise for COVID-19 treatment in animal model

In a recent study posted to the bioRxiv* pre-print server, researchers demonstrated that Nitazoxanide (NTZ), an oral drug, broadly inhibits replication of several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern (VOCs) in preclinical models of infection.

13 Feb 2022

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

MUSC Hollings Cancer Center researcher Sophie Paczesny, M.D., Ph.D., recently received a four-year grant from the National Heart, Lung, and Blood Institute to investigate solutions to help doctors to fight complications after pediatric bone marrow transplantation (BMT).

12 Feb 2022

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

A study in mice - led by researchers at Washington University School of Medicine in St. Louis - shows that a new class of compounds the scientists developed can improve multiple aspects of metabolic syndrome.

12 Feb 2022

Ketogenic diet could enhance the efficacy of chemotherapy for pancreatic cancer, study shows

A Ludwig Cancer Research preclinical study has demonstrated that a common weight-loss diet could enhance the efficacy of chemotherapy for pancreatic cancer.

12 Feb 2022

Mechanical clot removal may improve recovery after severe stroke in children

Serious disability was 6 times more likely to be the result three months after stroke among children whose clot-caused stroke in a large vessel (a type of ischemic stroke) was not treated with a procedure to extract the clot, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2022.

12 Feb 2022

Therapy News and Research

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A third known case of HIV remission involving stem cell transplant documented

This doctor thought she could navigate US health care. Then her autistic son needed help.

Regulating inflammation in Alzheimer's disease using a nanocleaner

Antiviral potential of N-acylethanolamine acid amide hydrolase against SARS-CoV-2 and Zika virus

Phase one study of oral SARS-CoV-2 antiviral agent nirmatrelvir

Studies compare endovascular therapy and microsurgery for treating wide-neck aneurysms

Enhanced external counterpulsation therapy benefits long COVID-19 patients

Impact of rapid and comprehensive RT-qPCR for detecting SARS-CoV-2 variants of concern

Study identifies a link between mortality of newborns on ECMO and red blood cell transfusion volume

Researchers identify a powerful combination of antivirals to treat COVID-19

Hundreds of new proteins that could play a role in cystic fibrosis discovered

Physicists investigate the usefulness of gene expression tests for cancer therapy

Novel tool for better dietary management in cancer patients

New research could deliver a breakthrough for kids suffering from severe form of genetic epilepsy

Nitazoxanide shows promise for COVID-19 treatment in animal model

Hollings researcher receives grant to fight complications after pediatric bone marrow transplant

New class of compounds can improve multiple aspects of metabolic syndrome, mice study shows

Ketogenic diet could enhance the efficacy of chemotherapy for pancreatic cancer, study shows

Mechanical clot removal may improve recovery after severe stroke in children

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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