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The painful side of positive health care marketing

Lori Wallace sits on a couch with her 11-year-old son and his new pet snake. It burrows under his armpit, as if afraid. Wallace is sure it’s not.

25 Oct 2017

Study reveals why Alzheimer's drugs fail in clinical trials

A tremendous amount of Amyloid-β peptide (Aβ) (a peptide of ～40 amino acids) accumulates in the brain of Alzheimer's disease patients. γ-Secretase inhibitors were designed to inhibit the enzymatic activity that produces Aβ. By reducing Aβ production, γ-secretase inhibitors were considered able to treat Alzheimer's disease (Aβ hypothesis).

25 Oct 2017

Long-term risk of premature death in men and women strongly associated with depression, study reveals

A Stirling County study, published in Canadian Medical Association Journal, suggests that depression remains strongly associated with a higher risk of early death in both men and women.

25 Oct 2017

New trial to assess effectiveness of self-management program for women with pelvic organ prolapse

A new £1.1million trial led by the University of Stirling will assess whether a self-management program could help to improve the lives of women who suffer pelvic organ prolapse.

25 Oct 2017

Researchers discover mechanism that corrects protein misfolding in plants

Various human nervous system diseases, such as amyotrophic lateral sclerosis (ALS), Alzheimer's, Huntington's, and Parkinson's diseases, are associated with the same basic disorder: the loss of nerve cells capacity to fold their proteins correctly, which causes protein aggregations that form "clumps" that end up generating the cell death.

25 Oct 2017

New discovery could speed development and approval of antiviral drugs

New research shows that a new class of antiviral drugs works by causing the virus' replication machinery to pause and backtrack, preventing the virus from efficiently replicating. This discovery, made possible by a high-throughput experimental technique called "magnetic tweezers," could speed the development and approval of related antiviral drugs.

25 Oct 2017

Hospitals need to improve emergency care practices for treating older cancer patients, study reveals

A new study finds that patients with cancer, especially those aged 75 or older, are more likely to be admitted to the hospital – and less likely to be observed and released home – than patients without cancer.

25 Oct 2017

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

New research from The University of Texas Health Science Center at San Antonio and U.S. Department of Veterans Affairs has identified the molecular mechanism that causes kidney cancer to resist drug treatment.

25 Oct 2017

Researchers mine blood-based epigenetic data to gain insights into autism biology

Using data from blood and brain tissue, a team led by researchers at Johns Hopkins Bloomberg School of Public Health found that they could gain insights into mechanisms that might help explain autism by analyzing the interplay between genes and chemical tags that control whether genes are used to make a protein, called epigenetic marks.

25 Oct 2017

Stony Brook University scientist receives $3.9 million NIH grant for ALS research

Stony Brook University scientist Josh Dubnau, PhD, has received a $3.9 million grant from the National Institutes of Health to investigate the impact of environmental stressors and other external factors that contribute to the development of amyotrophic lateral sclerosis (ALS).

24 Oct 2017

CRISPRy bacon ! Genetically modified leaner low-fat pigs

Genetically modified leaner pigs are on the cards soon. Researchers in china used the gene-editing technology, CRISPR, to create pigs that are less fatty and leaner with more muscle. This could mean genetically modified bacon on the plates.

24 Oct 2017

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

The genome editing tool known as CRISPR/Cas9 has opened many doors for biomedical research by allowing scientists to precisely edit DNA sequences and alter function. The technology offers hope for correcting genetic defects and preventing disease.

24 Oct 2017

Human exposure to glyphosate has increased significantly over 23 years, research finds

Analyzing samples from a prospective study, University of California San Diego School of Medicine researchers found that human exposure to glyphosate, a chemical widely found in weed killers, has increased approximately 500 percent since the introduction of genetically modified crops.

24 Oct 2017

Fight CRC and CRI announce publication of ‘A Blueprint to Advance Colorectal Cancer Immunotherapies’

Fight Colorectal Cancer and the Cancer Research Institute, are proud to announce "A Blueprint to Advance Colorectal Cancer Immunotherapies" will be published in the November 2017 issue of the journal Cancer Immunology Research (published online ahead of print on October 16, 2017).

24 Oct 2017

Myelin sheaths restore impaired nervous system over the long haul

In the central nervous system of humans and all other mammals, a vital insulating sheath composed of lipids and proteins around nerve fibers helps speed the electrical signals or nerve impulses that direct our bodies to walk, talk, breathe, swallow or perform any routine physical act.

24 Oct 2017

NIH launches major effort to discover, catalog the brain's ‘parts list’

The National Institutes of Health has launched a major effort to discover and catalog the brain's "parts list." The NIH's Brain Research through Advancing Innovative Neurotechnologies® Initiative Cell Census Network aims to provide researchers with a comprehensive reference of the diverse cell types in human, monkey, and mouse brain.

24 Oct 2017

Depression among nurses may increase likelihood of medical errors

Depression is common among nurses and is linked to a higher likelihood they'll make medical errors, new research suggests.

24 Oct 2017

APC gene mutations play dual role in development of colorectal cancer, research suggests

Adenomatous polyposis coli (APC) is a gene whose mutations are associated with a rare, hereditary form of colorectal cancer known as familial adenomatous polyposis. Research led by scientists at the Institut Pasteur and Inserm have recently demonstrated that mutations to this gene do not only lead to the emergence of colon polyps; they also harm the immune system, leaving it unable to tackle inflammation of the colonic mucosa.

24 Oct 2017

New ‘compressed sensing’ technology could reduce MRI scan times

Patients who have to undergo a magnetic resonance imaging scan may be spared the ordeal of having to lie still in the scanner for up to 45 minutes, thanks to new technology patented by Rice University, also known as "compressed sensing" technology.

24 Oct 2017

Study seeks views of perpetrators to understand effects of domestic violence on workplaces

Researchers at the Ontario Institute for Studies in Education at the University of Toronto and Western University released a new study today, taking an unconventional approach to understanding the significant effects of domestic violence in the workplace.

24 Oct 2017

Research News and Research

The painful side of positive health care marketing

Study reveals why Alzheimer's drugs fail in clinical trials

Long-term risk of premature death in men and women strongly associated with depression, study reveals

New trial to assess effectiveness of self-management program for women with pelvic organ prolapse

Researchers discover mechanism that corrects protein misfolding in plants

New discovery could speed development and approval of antiviral drugs

Hospitals need to improve emergency care practices for treating older cancer patients, study reveals

Research identifies molecular mechanism that causes kidney cancer to resist drug treatment

Researchers mine blood-based epigenetic data to gain insights into autism biology

Stony Brook University scientist receives $3.9 million NIH grant for ALS research

CRISPRy bacon ! Genetically modified leaner low-fat pigs

Scientists develop unique CRISPR-based method for more precise, systematic gene tagging

Human exposure to glyphosate has increased significantly over 23 years, research finds

Fight CRC and CRI announce publication of ‘A Blueprint to Advance Colorectal Cancer Immunotherapies’

Myelin sheaths restore impaired nervous system over the long haul

NIH launches major effort to discover, catalog the brain's ‘parts list’

Depression among nurses may increase likelihood of medical errors

APC gene mutations play dual role in development of colorectal cancer, research suggests

New ‘compressed sensing’ technology could reduce MRI scan times

Study seeks views of perpetrators to understand effects of domestic violence on workplaces

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