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Replication of SARS-CoV-2 variants in different cell and organ models

In this study, the replication of B.1.1.7 viruses was analyzed in different cell and organ models and dwarf hamsters.

22 Oct 2021

Bacteria defend themselves against viral predators with exchangeable genetic elements

Bacterial viruses, so-called phages, destroy bacteria. Bacteria are constantly exposed to viral attacks. A research team led by Martin Polz, a microbiologist at the University of Vienna, has now studied how bacteria defend themselves against viral predators.

22 Oct 2021

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Scientists studying the most common and aggressive type of brain tumor in adults have discovered a new way of analyzing diseased and healthy cells from the same patient.

22 Oct 2021

Honeybees can be trained to identify SARS-CoV-2 infected samples, say scientists

In a recent study published on the bioRxiv* pre-print server, researchers from the Netherlands successfully trained honeybees (Apis mellifera) to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected minks (Neovison vison) using Pavlovian conditioning protocols.

21 Oct 2021

Study finds distinct lower airways in children with cystic fibrosis

In the largest study of its kind, researchers found that the lower airways in children with cystic fibrosis (CF) have a higher burden of infection, more inflammation and lower diversity of microorganisms, compared to children with other illnesses who also have lung issues.

21 Oct 2021

Antisocial and prosocial behavior during COVID-19

A new study aims to determine whether individuals with antisocial behaviors are more susceptible to COVID-19.

21 Oct 2021

Researchers discover how Staphylococcus aureus protects itself against important antibiotic

The skin bacterium Staphylococcus aureus often develops antibiotic resistance. It can then cause infections that are difficult to treat.

21 Oct 2021

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Scientists at St. Jude Children's Research Hospital have shown that cell-free DNA from cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children treated for the brain tumor medulloblastoma.

21 Oct 2021

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

Every day, the human kidneys clean about 1,500 liters of blood by producing approximately 1–2 liters of urine. Thereby, the body gets rid of excess water and toxic waste products of the metabolism or also drugs and maintains the balance of water and minerals in the tissues.

21 Oct 2021

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

One in five cancers affects blood cells and lymph nodes, causing leukemias and lymphomas, respectively. Although their treatment with drugs has led to a great advance in their cure, there are cases where there is no clinical response or resistance to them is generated.

21 Oct 2021

Improper Z-RNA recognition contributes to pathogenesis of Aicardi-Goutières syndrome

Like DNA, RNA molecules contain information through unique combinations of four different nucleotides. However, through a molecular process called RNA editing, chemical changes can be made to adenosine nucleotides that convert them to a nucleotide called inosine by enzymes known as adenosine deaminases (ADARs).

21 Oct 2021

Innovative method greatly simplifies the complexity of delivering vaccines

Future vaccine delivery may rely on everyday items like BBQ lighters and microneedles, thanks to the ingenuity of a team of Georgia Institute of Technology and Emory University researchers.

21 Oct 2021

Pitt researchers to contribute to building an atlas of cellular senescence

Most cells throughout the body can divide and multiply to replace old cells and repair damaged tissue, but in response to certain stresses, cells can lose their ability to proliferate. These so-called senescent cells accumulate with age and may contribute to cancer and age-related disorders, such as chronic lung disease, cardiovascular disease, frailty and dementia, by pumping out signals that damage neighboring tissues.

21 Oct 2021

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

By combining computational and experimental approaches, University of Pittsburgh School of Medicine and Prairie View A&M University researchers identified cancer drugs that show promise for treating pulmonary hypertension, or PH, a rare and incurable lung disease.

21 Oct 2021

Research reveals the mechanisms of cardiac sex disparities at an early stage

Males and females differ in prevalence, treatment responses, and survival rates for a variety of diseases. For cardiac disease, women almost uniformly fare far worse than men. There are likely many reasons for this, and scientists at the University of North Carolina at Chapel Hill and Princeton University seemed to have found one deep inside cells before we're even born.

21 Oct 2021

Discovery could help develop a new treatment strategy for patients with melanoma

A new study led by Yale Cancer Center researchers shows that the enzyme KDM5B suppresses anti-melanoma immunity.

20 Oct 2021

Scientists search for cause of mysterious covid-related inflammation in children

Like most other kids with covid, Dante and Michael DeMaino seemed to have no serious symptoms.

20 Oct 2021

Research uncovers a new human sensory ability to detect sugars in the mouth

Most everyone understands that a major role of our sense of taste is to inform us when sugar is present in foods and beverages by eliciting sweetness on our tongues. A study led by the Monell Chemical Senses Center, published this month in PLOS ONE, identifies a new human sensory ability to detect sugars in the mouth with a molecular calorie detector, of sorts.

20 Oct 2021

Researchers identify new gene variants that may cause inherited retinal dystrophies

An international team of researchers, led by scientists at University of California San Diego and Shiley Eye Institute at UC San Diego Health, has broadened and deepened understanding of how inherited retinal dystrophies (IRDs) affect different populations of people and, in the process, have identified new gene variants that may cause the diseases.

20 Oct 2021

Understanding how brain cells talk could help find new treatments for neurological, psychiatric conditions

Experts from the University of Nottingham have discovered that reversing the modification of molecular messages at synapses in the human brain, may contribute to reversible mental health conditions such as anxiety, and memory diseases such as dementia.

20 Oct 2021

Genetic News and Research

Replication of SARS-CoV-2 variants in different cell and organ models

Bacteria defend themselves against viral predators with exchangeable genetic elements

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Honeybees can be trained to identify SARS-CoV-2 infected samples, say scientists

Study finds distinct lower airways in children with cystic fibrosis

Antisocial and prosocial behavior during COVID-19

Researchers discover how Staphylococcus aureus protects itself against important antibiotic

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Researchers identify a common gene variant that drives the efficiency and outcome of dialysis

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

Improper Z-RNA recognition contributes to pathogenesis of Aicardi-Goutières syndrome

Innovative method greatly simplifies the complexity of delivering vaccines

Pitt researchers to contribute to building an atlas of cellular senescence

Researchers employ novel algorithm to identify candidate cancer drugs for pulmonary hypertension

Research reveals the mechanisms of cardiac sex disparities at an early stage

Discovery could help develop a new treatment strategy for patients with melanoma

Scientists search for cause of mysterious covid-related inflammation in children

Research uncovers a new human sensory ability to detect sugars in the mouth

Researchers identify new gene variants that may cause inherited retinal dystrophies

Understanding how brain cells talk could help find new treatments for neurological, psychiatric conditions

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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