Therapy News and Research

RSS

Properties and pharmacokinetics an oral drug candidate for COVID-19 treatment

Researchers studied the preclinical PK) and in vitro ADME properties of GS-441524, a potential oral drug for COVID-19 treatment.

10 Feb 2022

Study tests efficacy of molnupiravir against SARS-CoV-2 VOCs in various animal models

A study published on the bioRxiv* preprint server evaluates molnupiravir against a panel of relevant VOCs using three efficacy models: primary human airway epithelium organoids, a ferret model of upper respiratory disease, and a Roborovski dwarf hamster model for severe COVID-19.

9 Feb 2022

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

Flow cytometry is a powerful and complex technology used to count, sort or measure characteristics of cells and to detect biomarkers.

9 Feb 2022

Researchers reveal new therapeutic way to block oncogenic RAS mutants

As a 10-year journey comes to fruition, MUSC Hollings Cancer Center researcher John O'Bryan, Ph.D., and colleagues have demonstrated a new therapeutic way to block a protein that is frequently mutated in cancers.

9 Feb 2022

Mechanical clot removal may be effective and lead to better outcomes for stroke patients

Stroke patients previously considered unlikely to survive without severe disability may regain far more function if the blood clots (which cause an ischemic stroke) are mechanically removed in addition to standard medical therapy, according to preliminary late-breaking research presented today at the American Stroke Association's International Stroke Conference 2022, a world premier meeting for researchers and clinicians dedicated to the science of stroke and brain health, held in person in New Orleans and virtually, Feb. 9-11, 2022.

9 Feb 2022

The serious risks COVID-19 may pose during pregnancy

Researchers report on the potential for serious maternal illness or death during or following a pregnancy complicated by COVID-19.

9 Feb 2022

Children’s National performs first-ever HIFU surgery on a pediatric patient with neurofibromatosis

Children's National Hospital successfully performed the first-ever high-intensity focused ultrasound (HIFU) surgery on a pediatric patient with neurofibromatosis (NF).

9 Feb 2022

Research reveals why Black women experience higher breast cancer mortality

New research from Sanford Burnham Prebys has revealed significant molecular differences between the breast cells of white and Black women that help explain why Black women experience higher breast cancer mortality.

9 Feb 2022

Scientists identify a new protein that prevents cancer cell migration

When tumors spread, cancer cells migrate to other parts of the body through the blood or lymphatic vessels. Scientists at the Institute of Science and Technology Austria have now found a new protein that prevents cancer cells from doing so by making them stick more tightly to their surroundings.

9 Feb 2022

30-year-old cancer drug could get another shot, study says

A study by Virginia Commonwealth University Massey Cancer Center researchers published in today's print edition of Molecular Cancer Therapeutics shows that triplatin is effective against triple negative breast cancer, which is the most aggressive form of breast cancer and has few targeted therapies.

9 Feb 2022

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Drugs which are commonly-used as the first line of treatment for colorectal cancer cause the tumor cells to oversecrete proteins known as mucins, according to a new study published today in the journal eLife.

9 Feb 2022

Defective mitochondrial DNA could be modified using gene-editing techniques

Defective mitochondria – the 'batteries' that power the cells of our bodies – could in future be repaired using gene-editing techniques.

8 Feb 2022

UTSA awarded $6.8 million grant to establish a Coccidioidomycosis Collaborative Research Center

Mycology and immunology researchers from The University of Texas at San Antonio have been selected to receive a five-year, $6.8 million grant from the National Institutes of Health to establish a San Antonio-based Coccidioidomycosis Collaborative Research Center (SA-CCRC) focused on developing therapeutics and vaccines against coccidioidomycosis.

8 Feb 2022

Novel diagnostic platform offers hope for early detection of cancer in patients with Barrett’s esophagus

On a mission to increase early detection of esophageal cancer, University of Colorado (CU) Cancer Center member Sachin Wani, MD, is leading a study to see if a novel diagnostic platform can help endoscopists better identify the disease in patients with a condition called Barrett's esophagus.

8 Feb 2022

Mechanical hearts can generate new muscle tissue in the failing human heart

Mechanical hearts spur some regeneration in dormant parts of failing hearts, according to a UT Southwestern pilot study that shows promise for developing regenerative heart therapies.

8 Feb 2022

Study assesses the effectiveness of e-cigarettes as a smoking cessation aid

Using e-cigarettes to stop smoking may result in fewer successful quit attempts than trying to quit using other smoking cessation aids, such as nicotine replacement therapy (NRT) or meds, suggests US research published online in the journal Tobacco Control.

8 Feb 2022

Huntsman Mental Health Institute joins a national collaborative effort to tackle mood disorders

Huntsman Mental Health Institute at the University of Utah was designated a Center of Excellence and member of the National Network of Depression Centers (NNDC), a consortium of leading academic medical centers working to accelerate research, education, and improved treatment options for people with depressive and bipolar illnesses.

8 Feb 2022

Therapy News and Research

Properties and pharmacokinetics an oral drug candidate for COVID-19 treatment

Study tests efficacy of molnupiravir against SARS-CoV-2 VOCs in various animal models

Novel immune-profiling method offers a powerful alternative to conventional flow cytometry

Researchers reveal new therapeutic way to block oncogenic RAS mutants

Mechanical clot removal may be effective and lead to better outcomes for stroke patients

The serious risks COVID-19 may pose during pregnancy

Children’s National performs first-ever HIFU surgery on a pediatric patient with neurofibromatosis

Research reveals why Black women experience higher breast cancer mortality

Scientists identify a new protein that prevents cancer cell migration

30-year-old cancer drug could get another shot, study says

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Defective mitochondrial DNA could be modified using gene-editing techniques

UTSA awarded $6.8 million grant to establish a Coccidioidomycosis Collaborative Research Center

Novel diagnostic platform offers hope for early detection of cancer in patients with Barrett’s esophagus

Mechanical hearts can generate new muscle tissue in the failing human heart

Study assesses the effectiveness of e-cigarettes as a smoking cessation aid

Huntsman Mental Health Institute joins a national collaborative effort to tackle mood disorders

Novel dietary tool aims to help cancer patients fight disease

Regulatory sequences in the genomes of mammals help explain how cancer invades normal tissues

Winners of the first CERF Medical Engineering Prize for ALS Research announced

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

Latest News