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Sex-determining gene in mosquitoes may help reduce disease transmission

Researchers with the Fralin Life Science Institute at Virginia Tech have identified a gene responsible for sex determination in mosquitoes that can transmit yellow fever, dengue, and chikungunya viruses.

22 May 2015

Splicing pattern of obesity, type 2 diabetes genes may contribute to pathophysiology of obesity

Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research from the University of Eastern Finland. Obesity leads to changes in the splicing pattern of metabolically relevant genes such as TCF7L2 and INSR, resulting in impaired insulin action.

22 May 2015

Industry leaders meet at Frost & Sullivan's GIL 2015: Europe in London to learn, share new strategies for innovation

Between 2012 and 2014, over 70 companies globally valued at more than $1 billion were start-ups with new business models that were unique and transformative. During the same period, most business model innovators have managed to produce consistently profitable returns with average revenue gain between 100 and 500 percent. The keys to these success stories have been connectivity and convergence with 50 percent of new start-ups launched on mobile platforms.

22 May 2015

Untangling the Web of Gene Expression

With enhancers and other regulatory elements often lying 10s to 100s of kilobases from the genes they affect, understanding the regulation of gene expression is an incredibly complex endeavor...

From Integrated DNA Technologies 21 May 2015

Clinicians play key role in making consumers aware of the threats of foodborne diseases

Food safety awareness is key to understanding the food safety issues on the horizon, and clinicians at hospitals and doctors' offices play a key role in ensuring consumers are aware of the threats of foodborne illness, said the University of Georgia's Michael Doyle.

21 May 2015

DF/BWCC introduces new website to provide information about precision cancer medicine

Precision cancer medicine - diagnosis and treatment based on the genetic abnormalities of a specific tumor - is playing an ever-larger role in cancer care. The field got a boost earlier this year when President Barack Obama proposed a $215 million federal Precision Medicine Initiative with cancer as one of its priorities.

21 May 2015

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

A molecule that helps control gene expression may play a role in controlling chemotherapy resistance among patients with the most common form of ovarian cancer.

21 May 2015

Celgene to use Cypher's Coral technology to find novel genomic biomarkers

Cypher Genomics, Inc., a leading genome informatics company, today announced a collaboration with Celgene Corporation to apply Cypher's Coral technology to discover novel genomic biomarkers that associate with patient response to innovative medicines.

20 May 2015

IDT facilitates versatile, scalable solution to enrich enhancer:promoter interactions

Advancing the development of novel methods for understanding gene expression, Integrated DNA Technologies has enabled Dr Jim Hughes, Associate Professor at the Weatherall Institute of Molecular Medicine, Oxford, UK, to optimize his unique Capture-C method, based on Chromosomal Conformational Capture (3C).

From Integrated DNA Technologies 20 May 2015

Researchers discover how and where chromosome fragile sites occur in human DNA

Using a novel method they developed to map chromosome breaks in a model organism, the budding yeast, Wenyi Feng, Ph.D., of Upstate Medical University and her colleagues have discovered new information as to how and where chromosome fragile sites can occur in human DNA. These sites are frequently observed in cancer cells and are responsible for causing genomic rearrangements.

15 May 2015

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Army scientists working to support the Ebola virus outbreak response in West Africa have established the first genomic surveillance capability in Liberia, enabling them to monitor genetic changes in the virus within one week of sample collection. An article describing their work was recently published ahead of print in the online edition of Emerging Infectious Diseases.

15 May 2015

Study evaluates prenatal nutrition and genome-wide DNA patterns in adults exposed to malnutrition

Researchers at Columbia University's Mailman School of Public Health and Leiden University in the Netherlands found that children whose mothers were malnourished at famine levels during the first 10 weeks of pregnancy had changes in DNA methylation known to suppress genes involved in growth, development, and metabolism documented at age 59.

15 May 2015

Ground-breaking discovery could revolutionise lupus treatments

A ground-breaking discovery by Monash University researchers could revolutionise treatments given to lupus sufferers, saving thousands of people each year from serious illness or death caused by secondary infections.

14 May 2015

New test could identify resistant tuberculosis faster

Tuberculosis (TB) disease rates in some parts of London are as high as in Sub-Saharan Africa, and drug-resistant strains are becoming increasingly common.

From Oxford Gene Technology 14 May 2015

HHMI selects two Boston University medical students to conduct full-time biomedical research

Two medical students from Boston University have been selected by the Howard Hughes Medical Institute to conduct full-time biomedical research in its Medical Research Fellows Program. Joseph Park and Jacqueline Estevez are two of the selected 68 top medical and veterinary students from 37 different schools in the United States to receive this honor.

14 May 2015

Blocking FGL2 protein may offer new approach to treating brain cancer

Blocking FGL2, a protein known to promote cancer, may offer a new strategy for treating brain cancer, according to a study at The University of Texas MD Anderson Cancer Center.

14 May 2015

UCL-led team develops new technique to find resistant TB faster

The time needed to genetically sequence the bacteria causing tuberculosis (Mtb) from patient samples has been reduced from weeks to days using a new technique developed by a UCL-led team. This could help health service providers to better treat disease, control transmission of this infection, and monitor outbreaks.

From Oxford Gene Technology 13 May 2015

Childhood cancer survivors more likely to be obese than healthy peers

Childhood cancer survivors - especially those whose treatment included brain irradiation or chemotherapy with glucocorticoids - are 14 percent more likely to be obese than their healthy peers.

12 May 2015

Novel insights into the genetics of autism

A study of 2,377 children with autism, their parents and siblings has revealed novel insights into the genetics of the condition.

12 May 2015

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Individuals with this altered gene have hereditary hypertension (high blood pressure) and at the same time a skeletal malformation called brachydactyly type E, which is characterized by unusually short fingers and toes. The effect on blood pressure is so serious that -- if left untreated -- it most often leads to death before age fifty.

11 May 2015

Genome News and Research

Sex-determining gene in mosquitoes may help reduce disease transmission

Splicing pattern of obesity, type 2 diabetes genes may contribute to pathophysiology of obesity

Industry leaders meet at Frost & Sullivan's GIL 2015: Europe in London to learn, share new strategies for innovation

Untangling the Web of Gene Expression

Clinicians play key role in making consumers aware of the threats of foodborne diseases

DF/BWCC introduces new website to provide information about precision cancer medicine

Non-coding micro RNA molecule may control chemotherapy resistance among ovarian cancer patients

Celgene to use Cypher's Coral technology to find novel genomic biomarkers

IDT facilitates versatile, scalable solution to enrich enhancer:promoter interactions

Researchers discover how and where chromosome fragile sites occur in human DNA

New genomics laboratory in Liberia enables scientists to monitor genetic changes in Ebola virus

Study evaluates prenatal nutrition and genome-wide DNA patterns in adults exposed to malnutrition

Ground-breaking discovery could revolutionise lupus treatments

New test could identify resistant tuberculosis faster

HHMI selects two Boston University medical students to conduct full-time biomedical research

Blocking FGL2 protein may offer new approach to treating brain cancer

UCL-led team develops new technique to find resistant TB faster

Childhood cancer survivors more likely to be obese than healthy peers

Novel insights into the genetics of autism

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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