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Novel vaccine approach for prostate cancer

Mayo Clinic investigators and collaborators from the United Kingdom cured well-established prostate tumors in mice using a human vaccine with no apparent side effects. This novel cancer treatment approach encourages the immune system to rid itself of prostate tumors without assistance from toxic chemotherapies and radiation treatments.

20 Jun 2011

New insight into progressive supranuclear palsy

There are new genetic clues on risk factors and biological causes of a rare neurodegenerative disease called progressive supranuclear palsy (PSP), according to a new study from an international genetics team led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

20 Jun 2011

Scientists reveal complex protein mechanism that regulates genes linked with cancer

Scientists at Memorial Sloan-Kettering Cancer Center in New York and at IRB Barcelona reveal the mechanism of action of a protein that is essential for life and is associated with disease.

17 Jun 2011

Specific lipid mixtures can overcome lethal effects of multidrug-resistant bacteria

"Super bugs," which can cause wide-spread disease and may be resistant to most, if not all, conventional antibiotics, still have their weaknesses. A team of Canadian scientists discovered that specific mixtures of antimicrobial agents presented in lipid (fatty) mixtures can significantly boost the effectiveness of those agents to kill the resistant bacteria.

17 Jun 2011

'Blue baby' study sheds light on basic biology

A newborn described as a "happy blue baby" because of her bluish skin color but healthy appearance made a small mark in medical history when one of her physicians discovered something new in her genes-the hemoglobin Toms River mutation.

17 Jun 2011

Transgenomic introduces Nuclear Mitome Test for diagnosis of mitochondrial disorders

Transgenomic, Inc. today announced the launch of the Nuclear Mitome Test, a genetic test to aid physicians in the diagnosis of mitochondrial disorders.

17 Jun 2011

Adaptimmune melanoma trial opening

Adaptimmune announced today that it has opened a Phase I/II, two cohort, open label clinical trial in metastatic melanoma at Washington University, St. Louis, Missouri.

16 Jun 2011

Cancer Research UK to launch genetic testing programme

Cancer Research UK's chief executive Harpal Kumar today spoke of a 'golden era' for cancer research as the UK is poised to lead the world in individualising the practice of medicine by understanding which treatments are best suited to an individual patient's particular genetic type of cancer.

16 Jun 2011

Potential new drug therapies targeting genetic mutations benefit lung-cancer patients

Some lung-cancer patients at UT Southwestern Medical Center are responding well to potential new drug therapies targeting genetic mutations. Their participation in a national study is helping to forge new avenues to attack the disease.

16 Jun 2011

Life Technologies introduces CytoTune-iPS Reprogramming Kit

Life Technologies Corporation today announced the launch of CytoTune-iPS Reprogramming Kit -- research technology that provides far improved efficiency over standard methods to develop induced pluripotent stem cells from human somatic cells.

16 Jun 2011

Exposure to asbestos can cause genetic somatic mutations in mammals

Mice inhabiting an area known for its high concentration of asbestos-contaminated dust, have a higher level of genetic somatic mutations, compared with other regions where asbestos pollution levels are lower.

16 Jun 2011

QIAGEN to acquire Ipsogen

QIAGEN N.V. has made an offer and entered into exclusive negotiations to purchase a 47% initial stake in Ipsogen S.A. and subsequently make a public offer to fully acquire a global leader in molecular profiling and personalized healthcare diagnostics for a broad range of hematological cancers.

From QIAGEN Manchester Limited 15 Jun 2011

Reovirus with paclitaxel, carboplatin can treat metastatic non-small cell lung cancer

A type of virus known as the human reovirus possesses a remarkable trait: It can replicate inside and kill cancer cells that feature a common mutation, while leaving the body's normal cells alone.

15 Jun 2011

Calcium-sensing receptor plays key role in lethal lung cancer complication

A protein previously thought not to exist in adult human lungs not only is present in normal and cancerous lung tissue, scientists have found, but it also has a major role in the development of a lethal complication of some lung cancers.

14 Jun 2011

JEM published paper identifies new gene mutations in patients with chronic lymphocytic leukemia

A paper published online on June 13 in the Journal of Experimental Medicine identifies new gene mutations in patients with chronic lymphocytic leukemia (CLL)—a disease often associated with lack of response to chemotherapy and poor overall survival.

14 Jun 2011

Scientists identify six influenza A viruses similar to 2009 pandemic strain

Scientists using new mathematical and computational techniques have identified six influenza A viruses that have particularly close genetic relationships to the H1N1 "swine" flu virus that swept through the United States beginning in the spring of 2009. That virus eventually killed almost 18,000 people worldwide.

14 Jun 2011

Mutation News and Research

Novel vaccine approach for prostate cancer

New insight into progressive supranuclear palsy

Scientists reveal complex protein mechanism that regulates genes linked with cancer

Specific lipid mixtures can overcome lethal effects of multidrug-resistant bacteria

'Blue baby' study sheds light on basic biology

Transgenomic introduces Nuclear Mitome Test for diagnosis of mitochondrial disorders

Adaptimmune melanoma trial opening

Cancer Research UK to launch genetic testing programme

Potential new drug therapies targeting genetic mutations benefit lung-cancer patients

Life Technologies introduces CytoTune-iPS Reprogramming Kit

Exposure to asbestos can cause genetic somatic mutations in mammals

QIAGEN to acquire Ipsogen

Reovirus with paclitaxel, carboplatin can treat metastatic non-small cell lung cancer

Calcium-sensing receptor plays key role in lethal lung cancer complication

JEM published paper identifies new gene mutations in patients with chronic lymphocytic leukemia

Scientists identify six influenza A viruses similar to 2009 pandemic strain

Astellas, Ambit Biosciences announce interim results from AC220 Phase 2 trial against AML

UC Davis, Jackson Laboratory and NCI partner for human clinical trials on cancer

Each one of us receives 60 new mutations in our genome from parents

Vertex VX-770 Phase 3 STRIVE study for cystic fibrosis demonstrates improvements in lung function

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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