Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

Hippocampal myo-inositol and cognitive ability in adults with Down Syndrome

Researchers from the Institute of Psychiatry at King's College London have identified a molecule that could be targeted to treat the cognitive impairment in people with Down syndrome.

7 Dec 2005

Functional amyloid formation within mammalian tissue

What do neurodegenerative diseases and suntans have in common? Scientists at the Scripps Research Institute have found an intriguing molecular connection.

7 Dec 2005

Cerebrospinal fluid analysis combined with brain scan predicts Alzheimer's

A combination of brain scanning with a new imaging agent and cerebrospinal fluid (CSF) analysis has left neuroscientists encouraged that they may finally be moving toward techniques for diagnosing Alzheimer's disease before its clinical symptoms become apparent.

5 Dec 2005

Findings may help in development of new anti-inflammatory compounds

Virginia Commonwealth University researchers studying the enzyme that triggers inflammation have found that it may be a target for a new class of anti-inflammatory drugs to treat arthritis, asthma, multiple sclerosis, lung and colon cancers and Alzheimer's disease.

2 Dec 2005

Cole Porter was wrong - love only lasts a year!

According to scientists, those who say that true love lasts a lifetime have got it completely wrong and in fact it only lasts a year.

2 Dec 2005

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia

Most people with a rare type of dementia called primary progressive aphasia (PPA) have a specific combination of prion gene variants, a new study shows.

28 Nov 2005

Persistent amyloidosis following suppression of Ab production in a transgenic model of Alzheimer disease

Alzheimer Disease (AD) is characterized by hallmark lesions called amyloid plaques in the brain.

20 Nov 2005

Genetically modified allow scientists to examine the potential usefulness of new therapies for Alzheimer's disease

Researchers with the University of Florida and the California Institute of Technology have developed a new strain of genetically modified mice that allow scientists to examine the potential usefulness of new therapies for Alzheimer's disease.

20 Nov 2005

Cholesterol lowering drugs, including statins, may slow the progression of Alzheimer's disease

Cholesterol lowering drugs, including statins, may slow the progression of Alzheimer's disease, concludes a study in the Journal of Neurology Neurosurgery and Psychiatry.

20 Nov 2005

Study suggests that subtle breakdowns in attention may offer a reliable clue to Alzheimer's-related dementia

People in early stages of Alzheimer's disease have greater difficulty shifting attention back and forth between competing sources of information, a finding that offers new support for theories that contend breakdowns in attention play an important role in the onset of the disease.

14 Nov 2005

Link between diet and epileptic seizures studied

Although the high-fat, calorie-restricted ketogenic diet (KD) has long been used to prevent childhood epileptic seizures that are unresponsive to drugs, physicians have not really understood exactly why the diet works.

13 Nov 2005

Lifelong exercise decreases cellular aging in the brain

In the first study to show that lifelong exercise decreases cellular aging in the brain, scientists from the McKnight Brain Institute of the University of Florida say that moderately active rats have healthier DNA and more robust brain cells than their less active counterparts. The research was presented at the Society for Neuroscience's 35th annual meeting in Washington, D.C.

13 Nov 2005

Those most at risk of Alzheimer's would allow loved ones enroll them in research

According to a new survey most people at high risk of Alzheimer's disease would be willing to have their loved ones enroll them in research studies when they could no longer give consent themselves.

8 Nov 2005

Should Alzheimer's sufferers take part in research?

Grandma has Alzheimer's disease - should you sign her up for a new research study, even if she doesn't really understand what it entails?

7 Nov 2005

Resveratrol effective in lowering amyloid-beta peptides

A study published in the November 11 issue of the Journal of Biological Chemistry shows that resveratrol, a compound found in grapes and red wine, lowers the levels of the amyloid-beta peptides which cause the telltale senile plaques of Alzheimer's disease.

7 Nov 2005

Protein alpha-synuclein associated with causing neurodegenerative conditions may actually protects against neurodegeneration

Researchers at UT Southwestern Medical Center have discovered that a protein associated with causing neurodegenerative conditions may, when appearing in normal amounts, actually protects against neurodegeneration.

7 Nov 2005

Scientists find new mechanism by which brain cells can be damaged during chronic neurodegenerative diseases

Scientists at the University of Rochester Medical Center have targeted a new culprit and method of attack on neurologic functions in diseases such as Alzheimer's and dementia associated with HIV.

7 Nov 2005

Protein called CHIP helps untangle protein misfolding in brain disease

Keeping the body and mind healthy depends on keeping cells healthy and functioning. This means that cells need a very robust quality-control system to repair or remove damaged or misshapen proteins. Protein handling is especially important in neurons because damage or death of brain cells causes neurological disease.

1 Nov 2005

iNOS inhibitors may be effective therapies for Alzheimer's disease

A noxious gas speeds up brain degeneration in Alzheimer's disease, according to a study in the November 7 issue of The Journal of Experimental Medicine.

1 Nov 2005

HapMap will give clues to many common diseases

Researchers say that they have completed a map that charts patterns of human genetic variation in the world population, to better understand human biology, evolution and how to diagnose diseases.

27 Oct 2005

Alzheimer's Disease News and Research

Further Reading

Hippocampal myo-inositol and cognitive ability in adults with Down Syndrome

Functional amyloid formation within mammalian tissue

Cerebrospinal fluid analysis combined with brain scan predicts Alzheimer's

Findings may help in development of new anti-inflammatory compounds

Cole Porter was wrong - love only lasts a year!

Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia

Persistent amyloidosis following suppression of Ab production in a transgenic model of Alzheimer disease

Genetically modified allow scientists to examine the potential usefulness of new therapies for Alzheimer's disease

Cholesterol lowering drugs, including statins, may slow the progression of Alzheimer's disease

Study suggests that subtle breakdowns in attention may offer a reliable clue to Alzheimer's-related dementia

Link between diet and epileptic seizures studied

Lifelong exercise decreases cellular aging in the brain

Those most at risk of Alzheimer's would allow loved ones enroll them in research

Should Alzheimer's sufferers take part in research?

Resveratrol effective in lowering amyloid-beta peptides

Protein alpha-synuclein associated with causing neurodegenerative conditions may actually protects against neurodegeneration

Scientists find new mechanism by which brain cells can be damaged during chronic neurodegenerative diseases

Protein called CHIP helps untangle protein misfolding in brain disease

iNOS inhibitors may be effective therapies for Alzheimer's disease

HapMap will give clues to many common diseases

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