Immune System News and Research

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Updated SSC Bundle aims to improve survival for sepsis patients

For patients with sepsis, a serious infection causing widespread inflammation, immediate treatment is essential to improve the chances of survival. An updated "Hour-1 Bundle" of the international, evidence-based guidelines for treatment of sepsis is introduced in the June issue of Critical Care Medicine.

18 May 2018

Study: Psoriasis patients taking Humira show no change in aortic inflammation

An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation – a key marker of future risk of major cardiovascular events – unlike other antibodies that target different aspects of the immune system.

18 May 2018

Study finds body temperature as major barrier to potential dengue, Zika vaccine

A major route toward creating effective vaccines against dengue virus and Zika involves the E protein that covers the surface of each viral particle.

18 May 2018

HIV patients on single-tablet regimen show better outcomes than those taking multiple pills

HIV patients on a single-tablet daily regimen had better treatment retention and viral suppression than patients taking multiple pills, in a study by a Michael E. DeBakey Veterans Affairs Medical Center researcher and his colleagues.

18 May 2018

Study: Macrophages play key role in maintaining stem cell niche of mammary gland

A new study finds that one of the toughest characters in the immune system, the macrophage, has a nurturing side, at least when it comes to guarding the developing breast.

18 May 2018

Study provides insights into how immune cells kill bacteria with acid

The first line of immune defense against invading pathogens like bacteria are macrophages, immune cells that engulf every foreign object that crosses their way. After enclosing it in intracellular membrane vesicles, a process called phagocytosis, macrophages kill their prey with acid.

17 May 2018

Scientists find how immune system helps to clear HBV infection after treatment interruption

Scientists from Karolinska Institutet and Hannover Medical School have published two studies that provide insights into how the immune system responds and helps to clear a hepatitis B infection after treatment interruption.

17 May 2018

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Alexo Therapeutics, a clinical-stage immuno-oncology company developing therapies to block the CD47 checkpoint mechanism, today announced it has initiated ALX148 combination dosing with targeted antibody therapies in its Phase 1 clinical program in patients with advanced solid tumors and lymphoma.

17 May 2018

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Cleveland Clinic researchers have demonstrated for the first time that lowering blood cholesterol levels could enhance the success of a specific type of T-cell immunotherapy in fighting cancer.

16 May 2018

Researchers discover a new antibody type

Researchers have made a discovery that contradicts previous understanding that an antibody only eliminates a specific subgroup of bacteria.

16 May 2018

Study finds distinct exhausted T cells that could have implications for fighting different diseases

The battle between the human immune system and long-term, persisting infections and other chronic diseases such as cancer results in a prolonged stalemate

16 May 2018

Scientists reveal active role of IgG antibodies in severity of anaphylaxis

The most severe allergic reaction, anaphylaxis, is the result of an inappropriate immune reaction following the introduction of a usually harmless antigen into the body.

16 May 2018

Immune system can produce 'universal antibodies' against various microorganisms

Bacteria and other microorganisms display structures from sugar molecules on their surfaces. These sugar structures play an important role for immune defense.

15 May 2018

Researchers discover unique mechanism that regulates tumor growth in lung cancer

Lung cancer is the third most common type of cancer in Germany and the disease affects both men and women. However, immunotherapies are successful in only 20 percent of cases.

14 May 2018

Study gives insight into how signals enter cancer cells and drive aggressive growth

The outside of a cancer cell is bombarded by signals. They come from the immune system, supporting tissues and other structures. But how do those signals impact cancer?

14 May 2018

New study to explore link between diet, intestinal microbiota and cognitive decline

Are abnormal intestinal microorganisms a risk factor for developing cognitive impairment? Researchers at Rush University Medical Center are trying to answer that question with a new study that will explore how the intestinal microbiota – the bacteria in the intestine –influence the progression of cognitive decline and the development of Alzheimer's disease.

14 May 2018

Overwhelming stress levels in Britain

According to a latest survey by the Mental Health Foundation, there is overwhelming stress that is being experienced by three quarters of Scots last year. The survey shows that a third of these people (over 35 percent) are suicidal due to the excessive stress that they are experiencing.

14 May 2018

New study aims to mitigate risks associated with treatment of multiple myeloma

In a 10-patient cohort study led by Dr. Jean Roy that aims to understand how to mitigate the risks associated with the treatment of multiple myeloma, a malignant cancer, researchers have adopted an innovative approach based on the unique immunological properties of umbilical cord blood in an effort to improve the safety and efficiency of allografting, the preferred treatment for this disease

11 May 2018

Addressing Antimicrobial Resistance Through Industry

Antimicrobial resistance is currently one of the biggest health threats in the world. Gary Cohen and Steve Conly discuss the role of Becton, Dickinson & Co and other organizations in the private sector in combating the spread of resistance.

11 May 2018

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates.

10 May 2018

Immune System News and Research

Updated SSC Bundle aims to improve survival for sepsis patients

Study: Psoriasis patients taking Humira show no change in aortic inflammation

Study finds body temperature as major barrier to potential dengue, Zika vaccine

HIV patients on single-tablet regimen show better outcomes than those taking multiple pills

Study: Macrophages play key role in maintaining stem cell niche of mammary gland

Study provides insights into how immune cells kill bacteria with acid

Scientists find how immune system helps to clear HBV infection after treatment interruption

Alexo Therapeutics marks next significant milestone by initiating ALX148 combination cohorts

Lowering blood cholesterol levels could enhance success of T-cell cancer immunotherapy

Researchers discover a new antibody type

Study finds distinct exhausted T cells that could have implications for fighting different diseases

Scientists reveal active role of IgG antibodies in severity of anaphylaxis

Immune system can produce 'universal antibodies' against various microorganisms

Researchers discover unique mechanism that regulates tumor growth in lung cancer

Study gives insight into how signals enter cancer cells and drive aggressive growth

New study to explore link between diet, intestinal microbiota and cognitive decline

Overwhelming stress levels in Britain

New study aims to mitigate risks associated with treatment of multiple myeloma

Addressing Antimicrobial Resistance Through Industry

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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