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Lives in danger as drug trial goes horribly wrong

In a drug trial which went horribly wrong two men are critically ill in a London hospital and four others are seriously ill, after suffering violent reactions to a new drug they took as part of a clinical trial.

16 Mar 2006

Fondaparinux significantly reduces risk of death for heart attack patients

Heart attack patients who have a certain pattern on an electrocardiogram significantly reduced their risk of death and having another heart attack at 30 days with the medication fondaparinux, without an increased risk of bleeding and strokes

15 Mar 2006

Use of high humidity does not improve symptoms of croup

For children with moderate to severe croup treated in the emergency department, use of high humidity did not improve symptoms more than low humidity or mist therapy, according to an article in the March 15 issue of JAMA: The Journal of the American Medical Association.

15 Mar 2006

Drug trial goes wrong and six end up intensive care

After taking part in a clinical trial of a new drug six men are now seriously ill in a north London hospital in the UK.

15 Mar 2006

Therapy for slightly raised blood pressure delays hypertension

A new study shows by giving a blood pressure drug to people with measurements above normal but not yet considered too high, the development of hypertension might be delayed.

15 Mar 2006

Researchers evaluate efficacy, safety of anti-clotting drugs

Patients admitted to the hospital with an acute coronary syndrome (ACS) are often treated with a catheter-based procedure known as percutaneous coronary intervention, or PCI.

15 Mar 2006

The safety and effectiveness of fondaparinux for heart attacks

The results of a large international cardiovascular trial will shed light on whether the addition of a new drug that prevents blood clotting, or thrombosis, can improve the treatment of the most serious form of heart attacks.

15 Mar 2006

Innovative treatment for critical limb ischemia

A new randomized study presented at the American College of Cardiology's 55th Annual Scientific Session investigates an innovative treatment for critical limb ischemia, or lack of arterial blood supply and oxygen to the legs, using a therapeutic approach to generate new blood vessels.

14 Mar 2006

Creative new therapies for atherosclerotic disease

Patients with a build-up of plaque in arteries in the heart, brain and leg face a high risk of major cardiovascular complications.

14 Mar 2006

Valproic acid may help slow the progression of dementia

Researchers have found that a common anticonvulsant drug improved cognitive function and appeared to restore nerve cells in the brains of patients with HIV-related dementia. The results of the Phase I clinical trial are published in the March issue of the scientific journal Neurology.

14 Mar 2006

Clopidogrel reduces risk of adverse events for patients with acute coronary syndromes undergoing balloon angioplasty

Patients with acute coronary syndromes who were pre-treated with the anti-platelet agent clopidogrel before undergoing a procedure such as balloon angioplasty or stent placement had a reduced risk of adverse events if they received the anti-clotting drug abciximab

14 Mar 2006

Can fixing the heart fix the head?

A study presented during the American College of Cardiology's inaugural Innovation in Intervention: The i2 Summit 2006 in Atlanta, Ga., will answer intriguing questions about whether repairing a hole in the heart known as a patent foramen ovale (PFO) can ease the pain of severe migraine headaches.

14 Mar 2006

Aspirin still the best for reducing the heart attack risk

New research has revealed that the addition of the blood-thinning drug Plavix to a daily dose of aspirin does not lower the risk of death, heart attack or stroke in high-risk patients.

13 Mar 2006

B vitamins and folic acid don't cut the risk of further heart attacks

Scientists have found that levels of the amino acid homocysteine may be high in people destined for a heart attack or stroke, and some studies in the past have linked homocysteine to an increased risk of heart disease.

13 Mar 2006

Using a growth factor to stimulate production of circulating endothelial progenitor cells improves cell production and mobility in arterial disease

Using a growth factor to stimulate production of circulating endothelial progenitor cells increases the numbers of these vascular regenerative cells, improves mobility, and potentially could improve blood vessel function in patients with peripheral arterial disease (PAD).

13 Mar 2006