Immune System News and Research

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Researchers manipulate bacterial species in the gut using diet

Scientists from Stanford University School of Medicine have shown that by manipulating diet in a mouse model, it is possible to favor the engraftment of a specific bacterial strain over others.

10 May 2018

Study: Environmental pollutants affect male reproduction in many species, including humans

In the St. Lawrence River near Montreal's sewage discharge site, male spottail shiners show the effects of pollution with more than one third of the fish having oocytes in their testes.

10 May 2018

Study finds neuroinflammation in spinal cord, nerve roots of patients with chronic sciatica

A study by Massachusetts General Hospital investigators has found, for the first time in humans, that patients with chronic sciatica - back pain that shoots down the leg - have evidence of inflammation in key areas of the nervous system.

10 May 2018

University of Utah announces new funding program to advance technology development and commercialization

The Center for Technology & Venture Commercialization at the University of Utah announced a new funding program for early stage technology development and commercialization.

10 May 2018

New case study shows CAR T therapy as viable option for AML patients

Chimeric Antigen Receptor T-cell therapy, also known as CAR T therapy, was named the biggest research breakthrough of 2017 by the American Society of Clinical Oncology. The personal gene therapy utilizes a patient's own immune cells to fight cancer.

9 May 2018

Human papilloma virus vaccines can protect against cervical lesions in young women

New evidence published today in the Cochrane Library shows that human papilloma virus vaccines protect against cervical lesions in young women, particularly in those who are vaccinated between the ages of 15 and 26.

9 May 2018

Baldness treatment using a medication for osteoporosis

According to researchers, a drug used to treat patients with osteoporosis may soon be helpful in treating baldness. The study was published in the latest issue of the journal PLOS Biology this week.

9 May 2018

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Neon Therapeutics, a clinical-stage immuno-oncology company developing neoantigen-based therapeutics, today announced that it has treated the first patient in a clinical trial evaluating its proprietary personal neoantigen vaccine, NEO-PV-01, in combination with Merck's anti-PD-1 therapy, KEYTRUDA®, along with chemotherapy.

8 May 2018

Scientists discover how protein molecules regulate formation of myelin sheaths

According to the Deutsche Multiple Sklerose Gesellschaft, around 200,000 people in Germany suffer from multiple sclerosis- a serious neurological condition that has no known cure.

8 May 2018

Night shifts may have negative impact on long-term health

A team of researchers from the McGill University affiliated Douglas Mental Health University Institute (DMHUI) has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns and that most of them stay tuned to their daytime biological clock rhythms.

8 May 2018

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Functional loss of ARID1a, a frequently mutated tumor suppressor gene, causes deficiencies in normal DNA repair and may sensitize tumors to immune checkpoint blockade therapies, according to researchers from The University of Texas MD Anderson Cancer Center.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

Study identifies molecule that may be critical to repair of white matter

A new study identifies a molecule that may be critical to the repair of white matter, the fatty tissue wrapped around parts of brain cells that helps speed up communication. Damage to white matter is associated with several conditions, including multiple sclerosis and cerebral palsy, and can occur in the brains of preterm babies.

7 May 2018

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Erythropoietin helps to protect and repair vulnerable brains though it remains a mystery how the anemia drug does so.

7 May 2018

Researchers uncover protein linked to breast cancer metastasis

Jean-François Côté, a researcher at the Montreal Clinical Research Institute and professor at Université de Montréal's Faculty of Medicine, studies metastasis, the leading cause of cancer-related death. Recently, his team uncovered a protein that, once deactivated, could prevent the development of metastases in an aggressive type of cancer, HER2-positive breast cancer.

7 May 2018

Stimulant use may negatively affect health of HIV-positive persons

A researcher at the University of Miami Miller School of Medicine has found that the use of stimulants, such as methamphetamine, can negatively affect the health of HIV-positive persons even when they are adhering to medical treatment.

4 May 2018

New research illustrates how beneficial bacteria establish robust gut colonization

The mammalian gut is warm, moist, and incredibly nutrient-rich--an environment that is perfect for bacterial growth. The communities of "good bacteria" in the gut, commonly referred to as the microbiome, are vital partners for the body, helping to digest fiber, extract nutrients, and prevent various diseases.

4 May 2018

Frequent sauna baths linked to lower stroke risk

Frequent sauna bathing is associated with a reduced risk of stroke, according to a new international study. In a 15-year follow-up study, people taking a sauna 4-7 times a week were 61% less likely to suffer a stroke than those taking a sauna once a week.

4 May 2018

UTSW study provides insight into potential new therapeutic approaches for skin diseases

Research at UT Southwestern has shown that targeting metabolism in growing cells holds promise for the treatment of skin diseases like psoriasis that are characterized by skin overgrowth resulting from excess cell division, known as hyperproliferation.

4 May 2018

Stiff tissue can present microenvironment susceptible to tumor growth, says study

Stiffer breast tissue creates an environment more prone to cancer by enabling the disease to interfere with the surrounding healthy cells, according to a recent study published in Biomaterials.

4 May 2018

Immune System News and Research

Researchers manipulate bacterial species in the gut using diet

Study: Environmental pollutants affect male reproduction in many species, including humans

Study finds neuroinflammation in spinal cord, nerve roots of patients with chronic sciatica

University of Utah announces new funding program to advance technology development and commercialization

New case study shows CAR T therapy as viable option for AML patients

Human papilloma virus vaccines can protect against cervical lesions in young women

Baldness treatment using a medication for osteoporosis

Neon Therapeutics evaluates safety, efficacy of NEO-PV-01 in combination with KEYTRUDA and chemotherapy

Scientists discover how protein molecules regulate formation of myelin sheaths

Night shifts may have negative impact on long-term health

Preclinical study suggests ARID1a mutations may help predict immunotherapy success

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Study identifies molecule that may be critical to repair of white matter

EPO's neuroprotective effect in preemies may be mediated by epigenetic regulation of genes

Researchers uncover protein linked to breast cancer metastasis

Stimulant use may negatively affect health of HIV-positive persons

New research illustrates how beneficial bacteria establish robust gut colonization

Frequent sauna baths linked to lower stroke risk

UTSW study provides insight into potential new therapeutic approaches for skin diseases

Stiff tissue can present microenvironment susceptible to tumor growth, says study

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