Infectious Diseases News and Research

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Genetic key to severe malaria resistance uncovered

Researchers have identified two genetic variants linked with human resistance to severe malaria.

21 Aug 2012

International guidelines improve outcomes after dental trauma

Adhering to the current International Association of Dental Traumatology guidelines for emergency treatment and care of traumatized teeth results in significantly lower complication rates, report researchers in Clinical Oral Investigations.

21 Aug 2012

CHD patients do not need to rule out high-intensity exercise

Findings from a retrospective study show that patients with coronary heart disease who engage in high-intensity exercise have a similarly low risk for a cardiovascular event as those engaging in moderate-intensity exercise.

21 Aug 2012

Declining circumcision rates in the US raise healthcare costs and disease risk

A team of disease experts and health economists at Johns Hopkins warns that steadily declining rates of U.S. infant male circumcision could add more than $4.4 billion in avoidable health care costs if rates over the next decade drop to levels now seen in Europe.

21 Aug 2012

Declining rates of circumcision in US infant males could add billions to health care costs

21 Aug 2012

Medivir initiates MIV-711 phase Ib trial in healthy volunteers

Medivir AB, the research-based pharmaceutical company focused on the development of high-value treatments for infectious diseases, is reporting today that a clinical phase Ib trial of the company's candidate drug (CD) MIV-711 has commenced.

21 Aug 2012

BioDiem and French partner VIVALIS a step forward in developing vaccines for diseases and related cancers

Australian infectious disease therapy and vaccine development company BioDiem Ltd (ASX: BDM) announced today successful results from two programs of work carried out by French partner VIVALIS (NYSE Euronext: VLS), confirming the ability of BioDiem’s Live Attenuated Influenza Virus (LAIV) to grow in VIVALIS’ proprietary EB66® cell line.

20 Aug 2012

Talk smoothes the way to better understanding sick babies

Clinicians must foster improved communication with the mothers of critically ill newborns to improve understanding of their child’s condition, research suggests.

20 Aug 2012

Infectious disease rates are high among homeless people

Rates of the infectious diseases HIV, Hepatitis C and tuberculosis among the world’s homeless people are many times higher than in the general population, according to a new systematic review of existing data published Online First in The Lancet Infectious Diseases.

20 Aug 2012

New birth-control strategy for mosquitoes can combat malaria

Using information about the unique mating practices of the male malaria mosquito ― which, unlike any other insect, inserts a plug to seal its sperm inside the female ― scientists are zeroing in on a birth-control drug for Anopheles mosquitoes, deadly carriers of the disease that threatens 3 billion people, has infected more than 215 million and kills 655,000 annually.

20 Aug 2012

New book on malaria tells story of Plasmodium falciparum Genome Project

Few infectious diseases can rival malaria's ability to kill and cripple. Each year the disease causes hundreds of millions of people to be sickened and more than a million - mostly African children under the age of five - die.

18 Aug 2012

Two Johns Hopkins scientists receive NCI grant for Provocative Questions project

Two Johns Hopkins scientists are among the first recipients of grants geared to answer "Provocative Questions" in cancer research, a new project funded by the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). Cynthia Sears, M.D., and Peter Searson, Ph.D., will receive more than $500,000 combined in the first of five years of funding.

17 Aug 2012

Curcumin shows promise in fighting devastating viruses

The popular spice turmeric packs more than just flavor - it shows promise in fighting devastating viruses, Mason researchers recently discovered.

17 Aug 2012

Medicago, IDRI receive FDA approval to commence Phase 1 H5N1 vaccine trial

The Infectious Disease Research Institute (IDRI), a Seattle-based non-profit research organization that is a leading developer of adjuvants used in vaccines combating infectious disease, and Medicago Inc., a biopharmaceutical company focused on developing highly effective and competitive vaccines based on proprietary manufacturing technologies and Virus-Like Particles (VLPs), announce that they have been cleared by the U.S. Food and Drug Administration (FDA) to initiate a Phase 1 clinical trial for an H5N1 Avian Influenza VLP vaccine candidate.

16 Aug 2012

Special device provides evidence of how bloodstream infections begin

New research may help explain why hundreds of thousands of Americans a year get sick - and tens of thousands die - after bacteria get into their blood. It also suggests why some of those bloodstream infections resist treatment with even the most powerful antibiotics.

16 Aug 2012

Genocea commences GEN-003 Phase 1/2a study in moderate-to-severe HSV-2 infection

Genocea Biosciences announced today that it has initiated a Phase 1/2a clinical study with its lead candidate, GEN-003. GEN-003 is an investigational vaccine designed to stimulate T cell and B cell immune responses to potentially reduce the frequency and severity of clinical outbreaks associated with moderate-to-severe Herpes Simplex Virus type 2 (HSV-2) infection.

16 Aug 2012

CD4 T cells orchestrate inflammatory attack on the artery wall

Most people probably know that heart disease remains the nation's No. 1 killer. But what many may be surprised to learn is that cholesterol has a major accomplice in causing dangerous arterial plaque buildup that can trigger a heart attack. The culprit? Inflammatory cells produced by the immune system.

15 Aug 2012