Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

The American Journal of Pathology: Highlights from February 2010 issue

A group led by Dr. Peter Lloyd Jones at the University of Dundee, Dundee, Scotland; the University of Colorado Denver, Aurora, CO; and the University of Pennsylvania, Philadelphia, PA has demonstrated that tenascin-C affects proto-oncogene function in breast cancer. Their report can be found in the February 2010 issue of The American Journal of Pathology.

22 Jan 2010

Current research suggests flu may predispose to secondary bacterial infections

Current research suggests that the flu may predispose to secondary bacterial infections, which account for a significant proportion of mortality during flu pandemics. The related report by Lee et al, "A mouse model of lethal synergism between influenza virus and Haemophilus influenzae," appears in the February 2010 issue of The American Journal of Pathology.

22 Jan 2010

Celerus Diagnostics demonstrates Rapid ISH on its Wave RPD System

Through collaborative efforts with multiple industry partners, Celerus Diagnostics has successfully demonstrated Rapid ISH™ (in-situ hybridization) on its forthcoming Wave RPD System.

21 Jan 2010

Loud music can increase risk for hearing loss

Listening to an iPod while working out feels like second nature to many people, but University of Alberta researcher Bill Hodgetts says we need to consider the volume levels in our earphones while working up a sweat.

21 Jan 2010

College of American Pathologists unveils resources and features on cancer in MyBiopsy.org

There's nothing more frightening than hearing the words "you have cancer" from your physician. With this diagnosis, many questions come to mind ... What's next? Will I survive? How do I tell my loved ones? The last is the most important for many people after receiving a cancer diagnosis: I need accurate information right now.

21 Jan 2010

Copper-free version of click chemistry crafted to create biomolecular probes

For the first time, the widely used molecular synthesis technique known as click chemistry has been safely applied to a living organism. Researchers with Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley have crafted a unique copper-free version of click chemistry to create biomolecular probes for in vivo studies of live mice. Conventional click chemistry reactions require a copper catalyst that is toxic to cells and organisms.

20 Jan 2010

TCGA study reveals four distinct molecular subtypes of GBM

The most common form of malignant brain cancer in adults, glioblastoma multiforme (GBM), is not a single disease but appears to be four distinct molecular subtypes, according to a study by the Cancer Genome Atlas (TCGA) Research Network. The researchers of this study also found that response to aggressive chemotherapy and radiation differed by subtype.

20 Jan 2010

Fraunhofer USA CMB receives $60,000 gift from ProTecs to complete vaccine manufacturing plant

The Fraunhofer USA Center for Molecular Biotechnology, a not-for-profit, 501 (c3) research organization, announced today that it has received a $60,000 gift from ProTecs, Inc., to complete its new, state of-the-art vaccine manufacturing plant in Newark, Delaware.

20 Jan 2010

New research at Rhode Island Hospital identifies a treatment for glioblastomas

New research at Rhode Island Hospital has identified a treatment in animal models for glioblastomas - deadly brain tumors which, once diagnosed, offer a poor prognosis and relatively short life expectancy.

20 Jan 2010

Repeated exposure to tobacco smoke makes lung cancer much worse

Repeated exposure to tobacco smoke makes lung cancer much worse, and one reason is that it steps up inflammation in the lung. Scientists at the University of California, San Diego School of Medicine have found that mice with early lung cancer lesions that were repeatedly exposed to tobacco smoke developed larger tumors - and developed tumors more quickly - than unexposed animals.

19 Jan 2010

More than half of women with DCIS are spared a mastectomy

Over 60 per cent of women who have a form of breast cancer in the milk ducts (DCIS) are spared a mastectomy, according to latest research published today in the British Journal of Cancer.

19 Jan 2010

AstraZeneca and Dako Denmark A/S enter into collaboration agreement

AstraZeneca and Dako Denmark A/S announced today that they have entered into a collaboration agreement to develop companion diagnostic tests for multiple AstraZeneca oncology projects, including biologics and small molecules, in various stages of discovery and development.

18 Jan 2010

Sunlight and vitamin D deficiency linked to 17 varieties of cancer

For humans, sunlight and vitamin D is critically important for the development, growth, and maintenance of a healthy body, from birth until death. "Humans make thousands of units of vitamin D within minutes of whole body exposure to sunlight. From what we know of nature, it is unlikely such a system evolved by chance," states Dr. John Cannell, Executive Director, Vitamin D Council.

18 Jan 2010

Down syndrome and Alzheimer's disease are the same

Nearly 20 years ago Huntington Potter kicked up a storm of controversy with the idea that Down syndrome and Alzheimer's were the same disease. Now the evidence is in: He was right.

18 Jan 2010

Breakthrough discovery could lead to new treatments for a variety of CNS disorders

A breakthrough discovery by scientists at the University of Kentucky could someday lead to new treatments for a variety of diseases of the brain, spinal cord and the eye.

18 Jan 2010

Three proteins that lead to memory loss associated with Alzheimer's disease identified

A scientific group led by the Translational Genomics Research Institute (TGen) have identified three kinases, or proteins, that dismantle connections within brain cells, which may lead to memory loss associated with Alzheimer's disease.

18 Jan 2010

Scientists discover potential biomarkers to predict the spread of colon cancer

Scientists in China are reporting discovery of two proteins present in the blood, of people with colon cancer that may serve as the potential biomarkers for accurately predicting whether the disease will spread.

18 Jan 2010

New class of drugs could help prevent skin cancer

A new study by Loyola University Health System researchers could lead to alternative treatments that would shrink skin cancer tumors with drugs. The drugs would work by turning on a gene that prevents skin cells from becoming cancerous, said senior author Mitchell Denning, Ph.D.

18 Jan 2010

Sudden deaths attributed to cocaine use; drug remains a growing health problem in Europe

Forensic pathologists have shown that over three per cent of all sudden deaths in south-west Spain are related to the use of cocaine. They believe their findings can be extrapolated to much of the rest of Europe, indicating that cocaine use is a growing public health problem in Europe and that there is no such thing as "safe" recreational use of small amounts of the drug.

13 Jan 2010

Obesity could lead to renal cell cancer: BJUI

Being obese could lead to a greater risk of developing the most common form of renal cell cancer, according to research in the January issue of the UK-based urology journal BJUI.

13 Jan 2010