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Genetic factors that make the bacteria behind cholera so dangerous uncovered

Study reveals key genetic factors in Vibrio cholerae O1 that drive cholera transmission and severity, highlighting targets for novel therapeutic strategies.

26 Sep 2024

Targeted drug therapy shows promise for ulcerative colitis remission

An international placebo-controlled study led by Cedars-Sinai suggests that a targeted drug therapy that was developed by researchers at Cedars-Sinai is safe and effective at helping people with moderate to severe ulcerative colitis reach clinical remission.

26 Sep 2024

Targeted therapy improves pregnancy outcomes

Amongst women who experience recurrent pregnancy loss, around 20% test positive for a specific antibody that targets the mother's own body. A Kobe University-led research team now found a treatment that drastically increases these women's chances of carrying to full-term without complications.

26 Sep 2024

Concerns raised over safety and effectiveness of donanemab for Alzheimer’s treatment

The safety and effectiveness of donanemab - an Alzheimer's drug recently approved by the US Food & Drug Administration (FDA) - is called into question in an investigation published by The BMJ today.

25 Sep 2024

New biomarker profiling enhances early detection of melanoma

Innovative research has unveiled promising advancements in melanoma detection, which could significantly enhance diagnosis and prognosis by identifying the disease at its earliest, most treatable stages.

25 Sep 2024

A faster, cheaper method to detect immune autoantibodies in whole blood

Researchers developed a quick and affordable whole-blood assay to detect autoantibodies against type I IFNs, enabling rapid diagnostics for immune disorders. This new method has potential clinical impact by addressing key limitations of current tests.

25 Sep 2024

Key triggers for food allergies in children after organ transplants

Study reviews transplant-acquired food allergies, focusing on pediatric patients, particularly liver transplant recipients. It explores immune system dysfunction, immunosuppressive agents, and gut microbiota changes as contributors to the rise of food allergies after organ transplants.

23 Sep 2024

Calcium channel blockers show potential to restore cerebral blood flow in Alzheimer's disease

Targeting calcium channels in pericytes may improve blood flow in Alzheimer's disease, addressing early vascular dysfunction linked to cognitive deficits.

23 Sep 2024

Dietary antigens reduce small intestine cancer by boosting immune T-cells

Study shows that dietary antigens can suppress small intestine carcinogenesis by activating T-cells through Peyer's patches. Adding bovine serum albumin (BSA) or ovalbumin (OVA) to antigen-free diets restored immune function and reduced tumor growth in mice.

22 Sep 2024

New two-dose HIV vaccine strategy shows promise for stronger immune response

One major reason why it has been difficult to develop an effective HIV vaccine is that the virus mutates very rapidly, allowing it to evade the antibody response generated by vaccines.

20 Sep 2024

Janus particles enable highly precise measurements in microfluidic devices

The importance of testing for diseases was thrust into the limelight during the COVID-19 pandemic. Many of us have undergone a PCR (Polymerase Chain Reaction) or ELISA (Enzyme-Linked Immunosorbent Assay) test within the past four years.

20 Sep 2024

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

A team of researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and The University of Texas M.D. Anderson Cancer Center, have reported safety and efficacy results from a Phase 1 trial that featured a personalized vaccine to treat lymphoplasmacytic lymphoma, a rare and slow-growing type of blood cancer, according to a study published recently in Nature Communications.

19 Sep 2024