Biochemistry News and Research

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Professor Sara Linse presents new data on protein interactions in Alzheimer’s disease using the Fluidity One-W at FEBS 2019

Fluidic Analytics’ diffusional sizing technology has been influential in a recent study that investigates protein binding and self-assembly in Alzheimer’s disease.

From Fluidic Analytics 8 Feb 2023

Researchers identify a new genetic risk factor for age-related macular degeneration

Researchers at Tel Aviv University identified a new genetic risk factor for the complex eye disease AMD (Age-related Macular Degeneration), a leading cause for loss of eyesight at an advanced age.

6 Feb 2023

Study identifies a drug candidate for the treatment of fatty liver disease

There is currently no drug for treating non-alcoholic fatty liver disease, which affects many people with type 2 diabetes and which can result in other serious liver diseases.

3 Feb 2023

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

Limb-girdle muscular dystrophy type 3 (LGMD D3) is a rare disease causing progressive muscle weakness, caused by point mutations in the hnRNPDL-2 protein.

3 Feb 2023

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

To commemorate World Cancer Day, we spoke to a multidisciplinary team of researchers from The Institute of Cancer Therapeutics (ICT) based at the University of Bradford about their work in cancer research.

3 Feb 2023

Research project aims to shed new light on how proteins in viruses bind to molecules

The way in which molecules interact forms the basis of life and treating illness. But what does it look like when a viral protein meets and binds to molecules like those found in medications? A new research project has been awarded DKK 65 million by the European Research Council and will now aim to shed light on this hitherto invisible process.

2 Feb 2023

UC Davis launches new institute to advance basic knowledge of psychedelics and neurotherapeutics

The University of California, Davis has launched the Institute for Psychedelics and Neurotherapeutics to advance basic knowledge about the mechanisms of psychedelics and translate it into safe and effective treatments for diseases such as depression, post-traumatic stress disorder, addiction, Alzheimer's disease and Parkinson's disease, among others.

2 Feb 2023

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

The Mays Cancer Center, home to UT Health San Antonio MD Anderson Cancer Center, was the lead site for a study evaluating Phase I and Phase III clinical trials for elacestrant, a treatment for postmenopausal women and adult men with ER+/HER2- advanced or metastatic breast cancer.

1 Feb 2023

Analysis of rebound virus suggests two separate reservoirs of latent HIV in patients

When people living with HIV take antiviral therapy (ART), their viral loads are driven so low that a standard blood test cannot detect the virus.

1 Feb 2023

Two million euro ERC Consolidator Grant awarded for finding new therapies against pancreatic cancer

The "Pancreatic ductal adenocarcinoma" (PDAC) is by far the most common form of cancer of the pancreas. PDAC tumors have an extremely poor prognosis because of several reasons.

31 Jan 2023

Machine learning identifies drugs that could be repurposed to help people quit smoking cigarettes

Medications like dextromethorphan, used to treat coughs caused by cold and flu, could potentially be repurposed to help people quit smoking cigarettes, according to a study by Penn State College of Medicine and University of Minnesota researchers.

30 Jan 2023

Survey: Trust in genetics increased significantly during the pandemic

A survey of over 2,000 British adults finds that trust in genetics is high and went up significantly during the pandemic. It also finds that there is a hunger for more coverage of genetics.

27 Jan 2023

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

Microtubules are cellular fibres that are part of the skeleton of the cell, termed cytoskeleton. They ensure that cells maintain their shape, carry out their functions, and divide.

27 Jan 2023

AI tool promises to accelerate the development of gene therapies on a large scale

An artificial intelligence (AI) program may enable the first simple production of customizable proteins called zinc fingers to treat diseases by turning genes on and off.

26 Jan 2023

Researchers gain systematic insight into the organization of proteins in mitochondria

Mitochondria, the so-called powerhouse of the cells, are responsible for the energy supply of the organism and fulfill functions in metabolic and signaling processes.

25 Jan 2023

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

According to the World Health Organization, each year there are an estimated 1 billion cases of influenza, between 3-5 million severe cases and up to 650,000 influenza-related respiratory deaths globally.

25 Jan 2023

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

RNA viruses, such as the coronavirus that causes COVID-19, are in a life-and-death race the moment they infect a cell.

25 Jan 2023

Study provides an estimate of people in the United States with VEXAS syndrome

About 13,200 men and another 2,300 women in the United States over age 50 are estimated to have VEXAS syndrome, according to a new study led by researchers at NYU Grossman School of Medicine.

24 Jan 2023

Study uncovers protein that acts as a brake for DNA replication

A protein that prepares DNA for replication also prevents the replication process from running out of control, according to a new study by Weill Cornell Medicine researchers.

24 Jan 2023

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

Ubiquigent Limited (Ubiquigent), a drug discovery and development company harnessing novel deubiquitinase (DUB) modulators as new therapeutics for areas of high unmet medical need, today announced it is supporting a Master’s student at the University of Glasgow (UoG) to undertake a research project on USP30, a DUB implicated in neurodegenerative, renal, and cardiovascular diseases.

From Ubiquigent Limited 23 Jan 2023

Biochemistry News and Research

Professor Sara Linse presents new data on protein interactions in Alzheimer’s disease using the Fluidity One-W at FEBS 2019

Researchers identify a new genetic risk factor for age-related macular degeneration

Study identifies a drug candidate for the treatment of fatty liver disease

Cryo-EM reveals the structure of hnRNPDL-2 protein fibrils associated with limb-girdle muscular dystrophy

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

Research project aims to shed new light on how proteins in viruses bind to molecules

UC Davis launches new institute to advance basic knowledge of psychedelics and neurotherapeutics

Mays Cancer Center leads a study evaluating Phase I and Phase III clinical trials for breast cancer drug

Analysis of rebound virus suggests two separate reservoirs of latent HIV in patients

Two million euro ERC Consolidator Grant awarded for finding new therapies against pancreatic cancer

Machine learning identifies drugs that could be repurposed to help people quit smoking cigarettes

Survey: Trust in genetics increased significantly during the pandemic

Researchers discover a key role played by ch-TOG protein in the initiation of microtubule assembly

AI tool promises to accelerate the development of gene therapies on a large scale

Researchers gain systematic insight into the organization of proteins in mitochondria

Atomic-level computer model of the H1N1 virus reveals new vulnerabilities

Cryo-electron microscopy reveals detailed blueprint of viral genome replication machinery

Study provides an estimate of people in the United States with VEXAS syndrome

Study uncovers protein that acts as a brake for DNA replication

Ubiquigent collaborates with University of Glasgow on translational structural biology to accelerate drug discovery within the (de)ubiquitylation field

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