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Professor Inga Neumann advances understanding of oxytocin and social fear

In a comprehensive Genomic Press Interview, Professor Inga Neumann, Chair of the Department of Behavioural and Molecular Neurobiology at the University of Regensburg, reveals groundbreaking insights into how oxytocin shapes social behavior and emotional responses in the brain.

24 Dec 2024

WHO TAG-CO-VAC reviews COVID-19 vaccine effectiveness and antigen composition

The WHO Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) continues to closely monitor the genetic and antigenic evolution of SARS-CoV-2 variants, immune responses to SARS-CoV-2 infection and COVID-19 vaccination, and the performance of COVID-19 vaccines against circulating variants.

24 Dec 2024

SPLICER shows promise in Alzheimer's and other diseases

A new gene editing tool that helps cellular machinery skip parts of genes responsible for diseases has been applied to reduce the formation of amyloid-beta plaque precursors in a mouse model of Alzheimer's disease, researchers at the University of Illinois Urbana-Champaign report.

23 Dec 2024

Advancing personalized nutrition through microbiome research

When making decisions about nutrition and diet, the focus is often on the potential impacts to the heart or brain; and gut health can frequently end up an afterthought despite a whole industry revolving around probiotics and digestive aids. With its direct link to those two important organs, should gut health be prioritized more?

23 Dec 2024

New insights into glioblastoma resistance to temozolomide

In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used as the front-line medicine in its treatment.

19 Dec 2024

Study finds facial shape differences linked to schizophrenia and bipolar disorder

A study published in Psychiatry Research identifies subtle differences in facial shapes that may be linked to the diagnosis of schizophrenia and bipolar disorder.

19 Dec 2024

Study reveals poor diet quality among pregnant and postpartum individuals

New research from the University of Massachusetts Amherst finds a pervasive low-quality diet among pregnant and postpartum individuals, reflecting "an urgent need for widespread improvement."

19 Dec 2024

Breakthrough study unravels molecular subtypes of breast cancer

Breast cancer, with its myriad subtypes, has long eluded a uniform treatment strategy. The disease's molecular complexity has rendered traditional, blanket treatments insufficient, particularly for the aggressive triple-negative form.

18 Dec 2024

Syphilis family traced to Pre-Columbian Americas

In spring 1495, the Italian campaign of Charles VIII of France was interrupted by an intense outbreak of an apparently unknown illness – a disease of high mortality that quickly engulfed the whole of Europe and left its survivors with life changing impairments to their bodies and minds.

18 Dec 2024

Genetic testing improves care for pediatric neurodevelopmental disorders

Adding genetic testing to the evaluation of pediatric patients with neurodevelopmental disorders (NDD) resulted in more individualized care, including changes in medication, referrals to clinical trials or specialists, and surveillance for potential medical issues, according to a new UCLA Health study.

18 Dec 2024

New study reveals complex attitudes toward psychedelic therapy

In a comprehensive Genomic Press Interview with researchers from Emory University, a new study published today reveals complex attitudes toward psychedelic therapy, with detailed statistics showing both strong support for potential benefits and significant awareness of risks.

18 Dec 2024

Research reveals how the brain processes fundamental learning calculations and social interactions

In a comprehensive Genomic Press Interview, Dr. Munir Gunes Kutlu, Assistant Professor at Temple University's Center for Substance Abuse Research, unveils revolutionary findings about how our brains process fundamental learning calculations and social interactions.

17 Dec 2024

Renowned neuroscientist reveals key insights into how brain circuits drive addictive behaviors

In a comprehensive Genomic Press Interview published today in Brain Medicine, renowned neuroscientist Dr. Peter Kalivas reveals crucial insights into how brain circuits drive addictive behaviors and discusses potential new drug targets for treating behavioral disorders.

17 Dec 2024

Gene variant in Andean populations could help predict blood cancer treatment outcomes

Two researchers from Huntsman Cancer Institute at the University of Utah (the U) have discovered a gene variant found in high-altitude Andean populations that they believe could be a new biomarker for predicting the severity of diseases and treatment responses for certain types of blood cancer.

14 Dec 2024

Researchers discover key genetic mechanism behind craniofacial development

An international team of researchers has identified a key genetic mechanism that regulates the formation and migration of cranial neural crest cells, which are essential for developing facial structures.

14 Dec 2024

Machine learning model predicts CDK4/6 inhibitor effectiveness in metastatic breast cancer

A machine learning (ML) model incorporating both clinical and genomic factors outperformed models based solely on either clinical or genomic data in predicting which patients with hormone receptor (HR)-positive, HER2-negative metastatic breast cancer would have better outcomes from adding CDK4/6 inhibitors to endocrine therapy as first-line treatment, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

Adjuvant anthracycline- plus taxane-based chemotherapy regimen improves survival in high-risk breast cancer patients

Patients with early-stage, node-negative, hormone receptor (HR)-positive, HER2- negative breast cancer who have a high risk of recurrence based on the OncotypeDX genomic test had better outcomes when treated with adjuvant anthracycline- plus taxane-based chemotherapy regimens compared with those receiving adjuvant taxane-based chemotherapy regimens alone, according to results presented at the San Antonio Breast Cancer Symposium (SABCS), held December 10-13, 2024.

14 Dec 2024

New protein platform enhances cancer immunotherapy

Researchers from Children's Hospital of Philadelphia (CHOP) and Stanford University have revealed the molecular structure of TRACeR-I, a protein platform for reprogramming immune responses. A better understanding of its structure may help optimize designs for the platform, which can be used to develop cancer treatments by either directly modifying immune cells or by creating proteins that help immune cells locate cancer cells. The findings were published today by the journal Nature Biotechnology.

13 Dec 2024

A genetic variant modulates interferon signaling and disease risk

For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There, when our cells sense an infection, they release a protein known as interferon, which warns other cells to fight the virus.

13 Dec 2024

Deep learning transforms PDAC diagnosis and treatment

Researchers have successfully developed a deep learning model that classifies pancreatic ductal adenocarcinoma (PDAC), the most common form of pancreatic cancer, into molecular subtypes using histopathology images.

13 Dec 2024