High Throughput News and Research

RSS

Deep learning-based splice-AI can help predict the onset of Alzheimer's disease

Korea Brain Research Institute (KBRI, President Suh Pann-ghill) announced that the research team led by Dr. Jae-Yeol Joo discovered new cryptic splice variants and SNVs in PLCg1 gene of AD-specific models for the first time using Splice-AI.

1 Mar 2021

New book focuses on rational drug design and discovery

Frontiers in Drug Design and Discovery is a book series devoted to publishing the latest and the most important advances in drug design and discovery.

25 Feb 2021

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

Many genetic variants have been found to have a linkage with genetic diseases, but the understanding of their functional roles in causing diseases are still limited.

24 Feb 2021

SARS-CoV-2 variants emerge during humoral immunity phase of acute COVID-19

A new preprint research paper posted to the bioRxiv server reports the rapid emergence of variants within an infected individual. The evolution of the virus within an infected host is not excluded by the close similarity between the consensus sequences of single-person SARS-CoV-2, since the number of viral copies is at its peak soon after infection occurs and before the host develops adaptive immunity.

23 Feb 2021

mRNA Therapeutics – Analytical and Bioanalytical Characterization

NewsMed interviews Anette Bak from AstraZeneca about her research on developments in mRNA therapeutics that she will present at Pittcon 2021.

From Pittcon 23 Feb 2021

Researchers create high throughput arrays of miniaturized 3D tumor models

By engineering common filter papers, similar to coffee filters, a team of NYU Abu Dhabi researchers have created high throughput arrays of miniaturized 3D tumor models to replicate key aspects of tumor physiology, which are absent in traditional drug testing platforms.

22 Feb 2021

Study finds potentially harmful chemicals in plastic toys

New research suggests that more than 100 chemicals found in plastic toy materials may pose possible health risks to children. The study provides findings that may lead to stricter international regulations.

22 Feb 2021

A promising strategy to improve functional capacity of damaged muscle

Muscle is the largest organ that accounts for 40% of body mass and plays an essential role in maintaining our lives.

21 Feb 2021

A different strategy for wastewater detection of SARS-CoV-2

Researchers tested a variety of RNA concentration and extraction methods and assays to develop a protocol for testing SARS-CoV-2 in wastewater, which may help improve COVID-19 surveillance.

21 Feb 2021

Novel gel electrophoresis method for MS-based quantification of protein biomarkers

Mass spectrometry (MS) is a powerful method for biomarker analysis because it enables highly sensitive and accurate measurement of target molecules in clinical samples.

18 Feb 2021

Cone snail venom could potentially treat severe forms of malaria

Severe forms of malaria such as Plasmodium falciparum may be deadly even after treatment with current parasite-killing drugs.

18 Feb 2021

Researchers find a way to improve deletion efficiency of new genome-editing tool

CRISPR deletion (CRISPR-del) is a new genome editing tool that can delete or cut out certain pieces of DNA in living cells with surgical precision.

17 Feb 2021

Analytical Chemistry of Beer and Brewing

NewsMed talks to Chris Welch about their Pittcon presentation on the analytical chemistry involved in beer brewing.

From Pittcon 17 Feb 2021

Novel polymer dots are a big step toward single-particle tissue imaging

A polymer that is custom designed to produce light that penetrates murky environments has shown promise in bioimaging trials, where it can detect nano-sized particles underneath the surface of realistic tissue models.

16 Feb 2021

What are the changes in the physical phenotype of blood cells in COVID-19?

While primarily a respiratory illness, there are distinctive alterations in the type and number of blood cells in COVID-19. A new study by a team of researchers in Germany describes the nature of these changes.

16 Feb 2021

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

A new preprint research paper posted to the bioRxiv server provides a greater understanding of the aspect of humoral immunity against the virus – the plasma cells that pour out a flood of specific antibodies targeting various epitopes on the pathogen.

16 Feb 2021

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

By capitalizing on a convergence of chemical, biological and artificial intelligence advances, University of Pittsburgh School of Medicine scientists have developed an unusually fast and efficient method for discovering tiny antibody fragments with big potential for development into therapeutics against deadly diseases.

15 Feb 2021

High-throughput sequencing could allow detection of new SARS-CoV-2 variants in wastewater

A new study reports the use of metagenomics to detect the virus from wastewater samples, indicating community-level circulating variants that are not yet identified or are present in very low proportions on clinical databases.

15 Feb 2021

Study offers new protocols for high-quality SARS-CoV-2 genomic sequencing

Researchers at the Southern Illinois University, U.S.A. have presented a comprehensive and well-validated set of working protocols for sequencing high-quality SARS-CoV-2 genomes in high throughput from patient samples.

12 Feb 2021

New SARS-CoV-2 variant found in newborn child with seizures in the United States

Researchers at a hospital in Washington D.C. found a new mutant strain of the virus in a neonatal patient with high viral loads. According to the authors, this strain could be spreading in the United States mid-Atlantic population and needs monitoring.

11 Feb 2021

High Throughput News and Research

Deep learning-based splice-AI can help predict the onset of Alzheimer's disease

New book focuses on rational drug design and discovery

High-throughput genetic analysis can help dissect the mechanism of disease inheritance

SARS-CoV-2 variants emerge during humoral immunity phase of acute COVID-19

mRNA Therapeutics – Analytical and Bioanalytical Characterization

Researchers create high throughput arrays of miniaturized 3D tumor models

Study finds potentially harmful chemicals in plastic toys

A promising strategy to improve functional capacity of damaged muscle

A different strategy for wastewater detection of SARS-CoV-2

Novel gel electrophoresis method for MS-based quantification of protein biomarkers

Cone snail venom could potentially treat severe forms of malaria

Researchers find a way to improve deletion efficiency of new genome-editing tool

Analytical Chemistry of Beer and Brewing

Novel polymer dots are a big step toward single-particle tissue imaging

What are the changes in the physical phenotype of blood cells in COVID-19?

Clonally expanded plasma cell lineages in SARS-CoV-2 produce specific neutralizing antibodies

Pitt scientists develop fast, efficient technique for discovering tiny antibody fragments

High-throughput sequencing could allow detection of new SARS-CoV-2 variants in wastewater

Study offers new protocols for high-quality SARS-CoV-2 genomic sequencing

New SARS-CoV-2 variant found in newborn child with seizures in the United States

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

Latest News