Lymph Nodes News and Research

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HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

Deregulation and inhibition of the immune system contributes to cancer development. Many therapeutic strategies aim to restimulate the immune system to recognize cancer cells and target them for destruction.

3 Jan 2017

Study suggests new options for improving cancer immunotherapy

One of the main reasons cancer remains difficult to treat is that cancer cells have developed a multitude of mechanisms that allow them to evade destruction by the immune system.

30 Dec 2016

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

The German Institute for Quality and Efficiency in Health Care (IQWiG) investigated the benefit of biomarker tests to support the decision for or against adjuvant systemic chemotherapy in certain breast cancer patients, that is, women with primary hormone receptor-positive, HER2-negative breast cancer and up to 3 affected lymph nodes.

30 Dec 2016

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

In experiments on mice with a form of aggressive brain cancer, Johns Hopkins researchers have shown that localized chemotherapy delivered directly to the brain rather than given systemically may be the best way to keep the immune system intact and strong when immunotherapy is also part of the treatment.

22 Dec 2016

High-fat, low-sugar diet prior to imaging can help reduce uncertainty in diagnosing cardiac sarcoidosis

Researchers at the University of Illinois at Chicago were able to reduce uncertainty in diagnosing cardiac sarcoidosis by having patients consume a high-fat, low-sugar diet for 72 hours prior to diagnostic imaging.

20 Dec 2016

Study provides new insights into fundamental characteristics of dendritic cells

Dendritic cells represent an important component of the immune system: they recognize and engulf invaders, which subsequently triggers a pathogen-specific immune response.

17 Dec 2016

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

Multiple sclerosis is an autoimmune disease in which the body's immune system attacks the patient's own cells.

1 Dec 2016

FDG PET-CT imaging helps assess anatomical structure and metabolic activity in patients with GLILD

A new proof of concept study has shown that an imaging technique more commonly used to assess cancer patients may also be of help in assessing disease and treatment effects in patients with inflammatory diseases.

30 Nov 2016

New study sheds light on how immune system functions during sleep

A new study sheds light on how the immune system replenishes itself during sleep. Researchers found that some subsets of T cells are reduced from the bloodstream during sleep when risk of infection is low.

16 Nov 2016

New Australian research shows how immune system avoids attacking own tissues with antibodies

New Australian research has shown how the immune system avoids attacking its own tissues with antibodies - whilst still maintaining a strong defence against invaders.

11 Nov 2016

Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

A study led by researchers at Beth Israel Deaconess Medical Center, in collaboration with scientists at Walter Reed Army Institute of Research, Janssen Vaccines & Prevention B.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson and Gilead Sciences, Inc., has demonstrated that combining an experimental vaccine with an innate immune stimulant may help lead to viral remission in people living with HIV.

9 Nov 2016

Investigational treatment combination improves virologic control in SIV-infected monkeys

Researchers have found that an investigational treatment combination of a therapeutic vaccine and an immune-stimulator improves virologic control and delays viral rebound following the discontinuation of antiretroviral therapy (ART) in non-human primates infected with SIV, the simian form of HIV.

9 Nov 2016

Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

McMaster University researchers have found that for patients diagnosed in the late stages of one of the most common and deadly forms of skin cancer, treatment with a combination of immunotherapy options improves survival and lowers the risk of life-threatening events.

7 Nov 2016

Combination of immunotherapy options improves survival of patients with deadly forms of skin cancer

5 Nov 2016

New Penn Medicine study raises questions about NLR as biomarker for bladder cancer

A blood test that has shown promise in predicting how cancer will progress and what treatments will be most effective for a given patient may not be reliable for either, according to a new Penn Medicine study published this week in Cancer, a peer-reviewed journal of the American Cancer Society.

27 Oct 2016

New approach could overcome large immunosuppressive tumors

Harnessing the body's own immune system to destroy tumors is a tantalizing prospect that has yet to realize its full potential. However, a new advance from MIT may bring this strategy, known as cancer immunotherapy, closer to becoming reality.

24 Oct 2016

New study examines how tumor genome testing helps improve breast cancer treatment

A new study examines how one early example of precision medicine--tumor genome testing--is being used in women with breast cancer to reduce overtreatment and maximize the benefits of chemotherapy.

24 Oct 2016

New oncogene may contribute to high incidence of prostate cancer among African American men

A team of scientists has identified MNX1 as a new oncogene - a gene than can cause cancer - that is more active in African American prostate cancer than in European American prostate cancer.

21 Oct 2016

UCSF researchers find active HIV in tissue samples of patients treated with antiretrovirals

While successful treatment of HIV with antiretroviral medications leads to undetectable levels of virus in the blood, controls the disease and leads to much longer lifespans, scientists know that HIV continues to reside in tissues.

21 Oct 2016

$Hypofractionated RT can reduce treatment time by half in stage II and III NSCLC patients$

Hypofractionated RT can reduce treatment time by half in stage II and III NSCLC patients

For patients with stage II and III non-small cell lung cancer (NSCLC) unable to receive standard treatments of surgery or chemoradiation (CRT), hypofractionated radiation therapy (RT) results in similar overall survival (OS) and progression-free survival (PFS) rates, limited severe side effects and shorter treatment times when compared to conventional RT, according to research presented today at the 58th Annual Meeting of the American Society for Radiation Oncology.

26 Sep 2016

Lymph Nodes News and Research

HER2-targeted dendritic cell vaccine shows promise for treating early-stage breast cancer patients

Study suggests new options for improving cancer immunotherapy

IQWiG investigates benefit of biomarker tests to support decision on adjuvant chemotherapy

Localized chemotherapy may be effective way to keep immune system intact, animal study suggests

High-fat, low-sugar diet prior to imaging can help reduce uncertainty in diagnosing cardiac sarcoidosis

Study provides new insights into fundamental characteristics of dendritic cells

Cluster signaling mechanism causes T cells to turn pathogenic in multiple sclerosis, research shows

FDG PET-CT imaging helps assess anatomical structure and metabolic activity in patients with GLILD

New study sheds light on how immune system functions during sleep

New Australian research shows how immune system avoids attacking own tissues with antibodies

Experimental vaccine/immune stimulant combination may lead to viral remission in HIV patients

Investigational treatment combination improves virologic control in SIV-infected monkeys

Combination of immunotherapy treatments can improve survival in patients with advanced skin cancer

Combination of immunotherapy options improves survival of patients with deadly forms of skin cancer

New Penn Medicine study raises questions about NLR as biomarker for bladder cancer

New approach could overcome large immunosuppressive tumors

New study examines how tumor genome testing helps improve breast cancer treatment

New oncogene may contribute to high incidence of prostate cancer among African American men

UCSF researchers find active HIV in tissue samples of patients treated with antiretrovirals

Hypofractionated RT can reduce treatment time by half in stage II and III NSCLC patients

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