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Drug-resistant bloodstream infections expected to rise across Europe by 2030

The rates of bloodstream infections caused by drug-resistant bacteria will increase substantially across Europe in the next five years, driven largely by aging populations, according to a new paper published November 4th in the open-access journal PLOS Medicine by Gwenan Knight of the London School of Hygiene and Tropical Medicine, UK, and colleagues.

5 Nov 2025

Survival patterns differ across types of early-onset dementia

The survival rates of people with early onset dementia-diagnosed before the age of 65-vary considerably by clinical type, but sex, age, family history and co-existing conditions aren't specific risk factors, finds research published online in the Journal of Neurology Neurosurgery & Psychiatry.

4 Nov 2025

Northwestern team develops antibody to expose hidden pancreatic cancer cells

Pancreatic cancer is notoriously hard to treat and often resists the most advanced immunotherapies. Northwestern Medicine scientists have uncovered a novel explanation for that resistance: Pancreatic tumors use a sugar-based disguise to hide from the immune system.

3 Nov 2025

COVID-19, RSV, and flu vaccines remain safe and effective

The systematic review provides crucial insights into the efficacy and safety of respiratory virus vaccines, supporting evidence-based immunization practices.

3 Nov 2025

Improving diagnosis, treatment and follow-up care for pulmonary embolism

Pulmonary embolism (PE), a type of blood clot in the lungs, sends more than half a million people to U.S. hospitals each year - and kills about one in five high-risk patients, according to the American Heart Association 2025 statistical update.

31 Oct 2025

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

Study reveals how TDP-43 causes neuronal overactivity in ALS and FTD

A new Northwestern University study using patient nervous tissue and lab-grown human neurons has uncovered how a key disease protein, TDP-43, drives overactive nerve cells in the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

31 Oct 2025

Life expectancy gains are slowing

Research shows life expectancy growth is slowing, with significant implications for health policies and individual planning in high-income nations.

31 Oct 2025

Better treatments buoy multiple-myeloma patients, bound by research cuts and racial disparities

For more than a year, Diane Hunter, now 72, had been experiencing vague symptoms — pain in her spine and hips, nausea, exhaustion, thirst, and frequent urination.

31 Oct 2025

Common viruses sharply raise heart attack and stroke risk, major global review shows

In the largest synthesis to date, researchers reviewed 155 studies linking viral infections, including influenza, SARS-CoV-2, HIV, hepatitis C, and shingles, to increased risks of coronary heart disease, stroke, and heart failure. The findings highlight viral infection prevention and vaccination as underappreciated strategies for cardiovascular protection.

30 Oct 2025

Study confirms PSA screening improves survival and safety

After 23 years of follow-up, the European Randomized Study of Screening for Prostate Cancer (ERSPC) confirmed a 13% lower prostate cancer mortality with PSA testing and an improved harm–benefit ratio over time. Risk-based screening could sustain mortality gains while reducing overdiagnosis and unnecessary treatment.

30 Oct 2025

Study uncovers neural mechanisms behind memory stabilization

Newly decoded brain circuits make memories more stable as part of learning, according to a new study led by NYU Langone Health researchers.

30 Oct 2025

Advances in diagnosis and management of systemic light chain amyloidosis

Systemic light chain (AL) amyloidosis is a rare and life-threatening disorder characterized by the deposition of misfolded immunoglobulin light chains as insoluble amyloid fibrils in various tissues and organs, leading to progressive structural and functional impairment.

30 Oct 2025

Therapeutic potential of Scleromitrion diffusum in gastric cancer treatment

Gastric cancer remains a major global health challenge, characterized by high mortality and limited therapeutic efficacy, especially in advanced stages.

30 Oct 2025

Understanding the role of m6A methylation in acute lung injury pathogenesis

Acute lung injury (ALI) is a critical clinical condition characterized by diffuse inflammation of the lung parenchyma and intractable hypoxemia, typically caused by factors, such as trauma, pneumonia, shock, and sepsis.

30 Oct 2025

Veterans with post-traumatic brain injury epilepsy more likely to have higher mortality rates

Military veterans who develop epilepsy after a traumatic brain injury may have a higher mortality rate in the following years than veterans who develop epilepsy with no previous traumatic brain injury, according to a study published on October 29, 2025, in Neurology®, the medical journal of the American Academy of Neurology.

30 Oct 2025

Research identifies biomarkers in blood to fine-tune breast cancer interventions

Doctors may be able to spare patients unnecessarily aggressive breast cancer treatments by collecting and testing cancer cells in patients' blood, research from the University of Michigan and the University of Kansas suggests.

30 Oct 2025

WHO reviews highlight limited long-term data on GLP-1 drug safety

Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions. The reviews were commissioned by the World Health Organization (WHO) to inform upcoming guidelines on the use of these drugs to treat obesity.

30 Oct 2025

Diets that harm the planet also raise the risk of cancer, heart disease, and diabetes

Diets that place greater pressure on the environment, high in meat and low in plant foods, were linked to higher risks of cancer, coronary heart disease, and type 2 diabetes in over 34,000 French adults. Sustainable, plant-rich diets were associated with better health and lower environmental impact.

29 Oct 2025

Diabetes remission possible with GLP-1 drugs, Italian study confirms

In a large real-world Italian cohort, GLP-1 receptor agonist therapy led to measurable rates of type 2 diabetes remission, depending on how remission was defined. The most pragmatic definition (Remission 3) was linked to improved glycemia, weight, and a lower risk of microvascular and cardiovascular events.

29 Oct 2025