Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Viewpoints: Debating P4P; ‘Tactical retreat' by GOP; The virtues of across-the-board spending cuts

Instead of granting automatic pay increases, N.Y. City's public hospital system will pay them based on how well they reduce costs, increase patient satisfaction and improve the quality of care. The Health and Hospitals Corporation, which runs the city's 11 public hospitals, deserves praise for an ambitious proposal that will need to be refined as it is put into practice.

28 Jan 2013

Hypertensive pregnancies need rigorous follow up

Women who have hypertensive complications during pregnancy are at increased risk for developing chronic kidney disease and end-stage renal disease, shows a study in the Canadian Medical Association Journal.

28 Jan 2013

Takeda receives FDA approval for Nesina, Kazano and Oseni to treat type 2 diabetes

The U.S. Food and Drug Administration today approved three new related products for use with diet and exercise to improve blood sugar control in adults with type 2 diabetes: Nesina (alogliptin) tablets, Kazano (alogliptin and metformin hydrochloride) tablets, and Oseni (alogliptin and pioglitazone) tablets.

28 Jan 2013

Kidney disease increases risk of premature death in diabetic patients

One in every 10 Americans has diabetes, and a third or more of those with the condition will develop kidney disease. It may be possible to live a long and healthy life with diabetes, but once kidney disease develops, the risk of dying prematurely increases significantly, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

25 Jan 2013

Ibuprofen and naproxen can cause kidney damage in children

Sick children, especially those with some dehydration from flu or other illnesses, risk significant kidney injury if given drugs such as ibuprofen and naproxen, Indiana University School of Medicine researchers said Friday.

25 Jan 2013

NSAIDs cause acute kidney injury in some children

Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, are commonly used to treat pain and reduce fever in children. However, the use of NSAIDs has been shown to cause acute kidney injury (AKI) in some children

25 Jan 2013

Researchers to develop new diagnostic tools and treatments for people with rare diseases

A multi-million Euro initiative is bringing together researchers from across the world to develop new diagnostic tools and new treatments for people with rare diseases and to connect research data in this area on a global scale.

25 Jan 2013

Galectin Therapeutics' GR-MD-02 reverses diabetic nephropathy in preclinical study

Galectin Therapeutics, the leading developer of therapeutics that target galectin proteins to treat fibrosis and cancer, today announced new preclinical data on the efficacy of anti-galectin therapy on diabetic kidney disease.

23 Jan 2013

Pregnant women with hypertensive disorders more likely to develop end-stage renal disease

Women with hypertensive disorders in pregnancy are at higher risk of chronic kidney disease and end-stage renal disease compared with women without the disorders, according to a study in CMAJ (Canadian Medical Association Journal).

22 Jan 2013

FDA approves Ampio’s IND for Optina for treatment of diabetic macular edema

Ampio Pharmaceuticals, Inc. announced today that the FDA has accepted the Company's IND for Optina™ for the treatment of diabetic macular edema (DME). Ampio plans to commence enrollment in a clinical trial in the first quarter of 2013. The FDA granted Optina™ 505(b)(2) status in July, 2012. Drugs designated under this pathway can be approved on a single trial.

22 Jan 2013

Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

Itch was actually defined by a German physician more than 350 years ago. His name was Samuel Hafenreffer. He defined itch as an unpleasant sensation that makes people want to scratch. You probably think this is a very simple definition but itch is really a very complex sensory modality.

21 Jan 2013

Atrial fibrillation increases risk of kidney failure in people with CKD

Many people who suffer from chronic kidney disease progressively lose their kidney function over time and eventually develop a condition called end-stage renal disease - the complete failure of the kidneys - placing them in need of lifelong dialysis or a kidney transplant.

18 Jan 2013

Top-line results from Amgen’s Aranesp Phase 3 trial on heart failure and anemia

Amgen today announced top-line results of the Phase 3 Aranesp (darbepoetin alfa) RED-HF (Reduction of Events With Darbepoetin Alfa in Heart Failure) Trial.

17 Jan 2013

BPA adversely affects kidney function in children

Children with high levels of exposure to bisphenol A are at increased risk for low-grade albuminuria, report researchers.

16 Jan 2013

Pediatric CKD rates increase substantially in south of England

Research shows that the number of children with moderate-to-severe chronic kidney disease in the south of England rose significantly between 2005 and 2009.

15 Jan 2013

NSAID–antihypertensive combinations may risk kidney damage

Physicians should be aware that treating patients with a combination of antihypertensives along with nonsteroidal anti-inflammatory drugs may cause kidney damage, say researchers.

14 Jan 2013

Angiotensin II blockade does not seem to provide benefit to kidney transplant recipients

A drug that protects the kidneys of patients with chronic kidney disease does not seem to provide the same benefit to kidney transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

11 Jan 2013

Study compares three treatment approaches in membranous nephropathy

The results of a pioneering UK-wide clinical trial that compared treatments for patients with a common type of kidney disease has found one to be significantly more effective. The results of the study, published online in The Lancet, will be recommended to clinicians worldwide as the most effective approach to treating the condition.

10 Jan 2013

Spectrum Pharmaceuticals reveals positive RenaZorb Phase 1 clinical trial results

Spectrum Pharmaceuticals, a biotechnology company with fully integrated commercial and drug development operations with a primary focus in hematology and oncology, today announced positive, statistically significant data from the Company's Phase 1 clinical trial evaluating the safety and tolerability of RenaZorb (also referred to as SPI-014) in healthy volunteers.

8 Jan 2013

Toxin-induced insulin resistance combated in mice

French researchers have found that a protein-bound uremic toxin, p-cresyl sulfate, contributes to the development of insulin resistance in mice, providing a new potential therapeutic target for treating chronic kidney disease, they say.

4 Jan 2013

Nephropathy News and Research

Further Reading

Viewpoints: Debating P4P; ‘Tactical retreat' by GOP; The virtues of across-the-board spending cuts

Hypertensive pregnancies need rigorous follow up

Takeda receives FDA approval for Nesina, Kazano and Oseni to treat type 2 diabetes

Kidney disease increases risk of premature death in diabetic patients

Ibuprofen and naproxen can cause kidney damage in children

NSAIDs cause acute kidney injury in some children

Researchers to develop new diagnostic tools and treatments for people with rare diseases

Galectin Therapeutics' GR-MD-02 reverses diabetic nephropathy in preclinical study

Pregnant women with hypertensive disorders more likely to develop end-stage renal disease

FDA approves Ampio’s IND for Optina for treatment of diabetic macular edema

Itch-specific nerve cells: an interview with Associate Professor Xinzhong Dong

Atrial fibrillation increases risk of kidney failure in people with CKD

Top-line results from Amgen’s Aranesp Phase 3 trial on heart failure and anemia

BPA adversely affects kidney function in children

Pediatric CKD rates increase substantially in south of England

NSAID–antihypertensive combinations may risk kidney damage

Angiotensin II blockade does not seem to provide benefit to kidney transplant recipients

Study compares three treatment approaches in membranous nephropathy

Spectrum Pharmaceuticals reveals positive RenaZorb Phase 1 clinical trial results

Toxin-induced insulin resistance combated in mice

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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